云南高校图书馆联盟文献共享服务平台- MELANOCYTES

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Cell Death of Tumor Melanocytes and Treatment Options: 《BIOCELL》2025年第3期355-379,共25页Olga Koval Maria Zhilnikova Maria Balantaeva Mikhail Biryukov Vasiliy Atamanov; supported by the Russian Science Foundation,project no.23-14-00285。; Melanomas are aggressive cancers,with a high rate of metastatic disease.Cutaneous(CM)and uveal(UM)melanomas are intrinsically different diseases,and most cell death inducers effective for CM do not function for UM.Thi...; 关键词：Cutaneous melanoma uveal melanoma cell death p53 ferroptosis cuproptosis immune checkpoints inhibitors immunogenic cell death tyrosinase-related protein 1 gp100

Nigella sativa L.seed extract alleviates oxidative stress-induced cellular senescence and dysfunction in melanocytes: 《Chinese Journal of Natural Medicines》2025年第2期203-213,共11页Ben Niu Xiaohong An Yongmei Chen Ting He Xiao Zhan Xiuqi Zhu Fengfeng Ping Wei Zhang Jia Zhou; supported by the National Natural Science Foundation of China (Nos.81973410 and 82473537);the Independent Research Fund of Yunnan Characteristic Plant Extraction Laboratory (Nos.2022YKZY002 and 2022YKZY004)。; Nigella sativa L.seeds have been traditionally utilized in Chinese folk medicine for centuries to treat vitiligo.This study revealed that the ethanolic extract of Nigella sativa L.(HZC)enhances melanogenesis and mitig...; 关键词：Nigella sativa L.seed extract(HZC) MELANIN ROS VITILIGO Cellular senescence

Decoding the Molecular Mechanisms of BRAFV600E-Induced Nevi Formation被引量：1: 《Biomedical and Environmental Sciences》2024年第7期774-784,共11页Weizheng Liang Yuxuan Liu Dandan Xu Wenjie Jiang Rensen Ran; Melanocytes derived from neural crest cells harbor the BRAFV600E mutation,which is the predominant driver of nevus formation in humans.This mutation leads to malignant cell proliferation and subsequent cell cycle arre...; 关键词：BRAFV600E MELANOCYTES NEVI Oncogene-induced senescence Animal models

Targeting senescent dermal fibroblasts responsible for hyperactive melanocytes in melasma: 《Chinese Medical Journal》2023年第13期1563-1565,共3页Jing Wan Zhikai Liao Bingqi Dong Shan Jiang Tiechi Lei; National Natural Science Foundation of China(Nos.81972919,82273513); Melasma(chloasma)is a highly prevalent and cosmetically disfiguring pigmented skin disease that mainly manifests as bilateral irregular brown macules on sun-exposed areas of the face.[1]Although melasma causes no phys...; 关键词：cytes SUSTAINED melan

MicroRNA-370-5p inhibits pigmentation and cell proliferation by downregulating mitogen-activated protein kinase kinase kinase 8 expression in sheep melanocytes: 《Journal of Integrative Agriculture》2023年第4期1131-1141,共11页JI Kai-yuan WEN Ru-jun WANG Zheng-zhou TIAN Qian-qian ZHANG Wei ZHANG Yun-hai; funded by the Natural Science Foundation of Anhui Province,China(2008085QC158);the University Natural Science Research Project of Anhui Province(KJ2019A0165)。; In mammals,microRNAs(miRNAs)play key roles in multiple biological processes by regulating the expression of target genes.Studies have found that the levels of miR-370-5p expression differ significantly in the skins of...; 关键词：MICRORNA mitogen-activated protein kinase kinase kinase 8 MELANOGENESIS sheep melanocytes cell proliferation

Exosomes released by melanocytes modulate fibroblasts to promote keloid formation: a pilot study被引量：4: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2022年第8期699-704,共6页Zeren SHEN Jinjin SHAO Jiaqi SUN Jinghong XU; supported by the Zhejiang Provincial Natural Science Foundation of China(No.LQ22H150005);the National Natural Science Foundation of China(No.81873937)。; Keloids are a common type of pathological scar as a result of skin healing,which are extremely difficult to prevent and treat without recurrence.The pathological mechanism of keloids is the excessive proliferation of ...; 关键词：al. HEALING cytes

Difficulties in diagnosing anorectal melanoma: A case report and review of the literature: 《World Journal of Clinical Cases》2021年第36期11369-11381,共13页Raluca Cristina Apostu Elena Stefanescu Radu Razvan Scurtu Gabriel Kacso Radu Drasovean; BACKGROUND Anorectal melanoma is a tumour that is difficult to identify due to its rarity and variability of presentation.Insufficient data published in the literature do not allow for diagnostic and treatment guideli...; 关键词：Mucosal melanoma ANORECTAL IMMUNOHISTOCHEMISTRY MELANOCYTES Molecular targeted therapy Case report

SFRP5 inhibits melanin synthesis of melanocytes in vitiligo by suppressing the Wnt/b-catenin signaling被引量：5: 《Genes & Diseases》2021年第5期677-688,共12页Daopei Zou Yangmei Chen Lingzhao Zhang Xiaohui Yuan Yujie Zhang Adelina Inggawati Pham Thi Kieu Nguyet Tianwen Gao Jin Chen; This work was supported by the National Natural Science Foundation of China[grant number 81773307];a research grant from Chongqing Science and Technology Commission[grant number cstc2018jcyjAX0195].; Secreted frizzled-related protein 5(SFRP5)plays a pivotal role in regulating the development of many tissues and organs,however,as an inhibitor of Wnt signaling,the role of SFRP5 in vitiligo remains unknown.Hence,we s...; 关键词：Melanin synthesis MELANOCYTES MITF SFRP5 VITILIGO Wnt signaling

Mobilization of Melanocytes During NB-UVB Treatment of Vitiligo被引量：1: 《International Journal of Dermatology and Venereology》2021年第3期163-167,共5页Yue Li Ru-Zhi Zhang; The authors are very grateful to Professor V.J.Hearing for help with the English-language editing.The work was supported by the National Nature Science Foundation of China(No.81673078).; Vitiligo,a common skin depigmentation disorder,is the result of complex interactions of genetic,immunological,environmental,and biochemical events.Treatments for vitiligo include drugs,phototherapy,surgical transplant...; 关键词：VITILIGO narrow band-ultraviolet B MELANOCYTE REPIGMENTATION

A Study of Normal Epidermal Melanocyte Distribution: 《International Journal of Dermatology and Venereology》2021年第1期32-35,共4页Kai-Lv Sun Wan Liu Xiao-Man Gao Min Yang Jian-Min Chang; Objective:To elucidate the epidermal melanocyte distribution according to sex,age,and body part with the goal of providing benchmark data for the diagnosis and therapeutic effect evaluation of pigmentary skin diseases...; 关键词：DISTRIBUTION IMMUNOFLUORESCENCE MELANOCYTES

MELANOCYTES