MEFLOQUINE

作品数：7被引量：32H指数：2
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相关领域：医药卫生更多>>
相关作者：胡康洪魏艳红王文琦更多>>
相关机构：湖北工业大学东莞市人民医院史密丝克莱恩贝克曼公司更多>>
相关期刊：《Journal of Otology》《Chinese Medical Journal》《World Journal of Clinical Cases》《Neuroscience Bulletin》更多>>
相关基金：国家重点基础研究发展计划国家自然科学基金更多>>
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Repurposing of clinically approved drugs for treatment of coronavirus disease 2019 in a 2019-novel coronavirus-related coronavirus model被引量：20
《Chinese Medical Journal》2020年第9期1051-1056,共6页Hua-Hao Fan Li-Qin Wang Wen-Li Liu Xiao-Ping An Zhen-Dong Liu Xiao-Qi He Li-Hua Song Yi-Gang Tong 
This work was supported by a project from Ministry of Science and Technology of China(No.2020YFC0840805);Key Project of Beijing University of Chemical Technology(No.X K 1803-06),Fundamental Research Funds for Central Universities(No.BUCTRC201917),and a.start-up funding for Dr.Yi-Gang Tong from Beijing Advanced Innovation Center for Soft Matter Science and Engineering.
Background:Medicines for the treatment of 2019-novel coronavirus(2019-nCoV)infections are urgently needed.However,drug screening using live 2019-nCoV requires high-level biosafety facilities,which imposes an obstacle ...
关键词：Coronavirus disease 2019 2019-Novel coronavirus CEPHARANTHINE SELAMECTIN Mefloquine hydrochloride 
Dependence of Generation of Hippocampal CAI Slow Oscillations on Electrical Synapses被引量：1
《Neuroscience Bulletin》2020年第1期39-48,共10页Yuan Xu Feng-Yan Shen Yu-Zhang Liu Lidan Wang Ying-Wei Wang Zhiru Wang 
This work was supported by grants from the National Natural Science Foundation of China(3147107,91132711,30970960);a Key Project of Shanghai Science and Technology Commission(15JC1400102,19ZR1416600).
Neuronal oscillations in the hippocampus are critical for many brain functions including learning and memory.The underlying mechanism of oscillation generation has been extensively investigated in terms of chemical sy...
关键词：Electrical synapse HIPPOCAMPUS OSCILLATION CA1 MEFLOQUINE Carbenoxolone Introduction 
Evidence for Neurotoxicity from Quinoline Antimalaria Drugs: Four Personal Accounts
《Open Journal of Animal Sciences》2017年第1期45-55,共11页Ashley M. Croft Anthony R. Mawson 
Background: The adverse effects of mefloquine and other quinoline antimalaria drugs can be severe and long-lasting. We believe that the trigger for these effects may be drug-induced hepatocellular damage that causes, ...
关键词：AFGHANISTAN Bales Lariam MALARIA MEFLOQUINE Pibloktoq 
Epilepsy triggered by mefloquine in an adult traveler to Uganda被引量：2
《World Journal of Clinical Cases》2014年第1期12-15,共4页Federico Gobbi Andrea Rossanese Dora Buonfrate Andrea Angheben Chiara Postiglione Zeno Bisoffi 
We report a case of a traveler who visited Uganda for 8 d, and took mefloquine one tablet/week for malaria prophylaxis. After the second dose, he suffered from two episodes of loss of consciousness with seizures, ther...
关键词：MEFLOQUINE NEUROPSYCHIATRIC disorders EPILEPSY ANTIMALARIAL CHEMOPROPHYLAXIS Side effects 
Detection of apoptosis by RT-PCR array in mefloquine-induced cochlear damage被引量：9
《Journal of Otology》2011年第1期1-9,共9页DING Da-lian Someya Shinichi JIANG Hai-yan QI Wei-dong YU Dong-zhen 
Objective To investigate the occurrence and possible mechanisms of apoptosis in cochlear epithelium and spiral ganglion neurons after mefloquine treatment. Methods We used quantitative RT-PCR apoptosis-focused gene ar...
关键词：MEFLOQUINE OTOTOXICITY APOPTOSIS COCHLEA spiral ganglion neurons hair cells gene expression 
Ototoxic effects of mefloquine in cochlear organotypic cultures被引量：2
《Journal of Otology》2009年第2期76-85,共10页Richard Salvi 
Mefloquine is a widely used anti-malarial drug. Some clinical reports suggest that mefloquine may be ototoxic and neurotoxic, but there is little scientific evidence from which to draw any firm conclusion. To evaluate...
关键词：MEFLOQUINE OTOTOXICITY NEUROPATHOLOGY outer hair cell inner hair cell spiral ganglion NEURONS axon degeneration 
Efficacy of dihydroartemisinin-mefloquine on acute uncomplicated falciparum malaria
《Chinese Medical Journal》2001年第6期52-53,105-106,共4页王文琦 杨伟 
Objective　To evaluate the clinical efficacy of dihydroartemisinin-mefloquine on acute uncomplicated falciparum malaria. Methods　Fifty-four patients with symptomatic falciparum malaria were allocated to receive oral ...
关键词：malaria   ·  Plasmodium falciparum  ·  dihydroartemisinin  ·  mefloquine 
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