This work was supported by the Japan Society for the Promotion of Science(JSPS)Grants-in-Aid for Scientifc Research(KAKENHI)(Grant Nos.26281048 and 21H03619).
Diuron is one of the most frequently applied herbicides in sugarcane farming in southern Japan,and Australia.In addition,it is used as a booster substance in copper-based antifouling paints.Due to these various uses,D...
This work was supported by the National Institute of General Medical Sciences of the National Institutes of Health under award number R01GM134125.
In a recent article published in Nature,Sen Santara et al.report a general mechanism that allows endoplasmic reticulum(ER)stress,a common response to many cellular dysfunctions,to signal to natural killer(NK)cells to ...
supported by The Biomechanics and Bio-materials Research Center at Indiana University-Purdue University Indianapolis,USA(No.2201-01);The NIH/Eunice Kennedy Shriver NICHD,USA(No.P50HD090215);The NIH/NCI Cancer Center Support Grant,USA(No.P30CA082709);The Tyler Trent Cancer Research Endowment for the Riley Hospital for Children IU-Health,USA;The Indiana University Grand ChallengeePrecision Health Initiative,USA.
Cancer cells tend to develop resistance to chemotherapy and enhance aggressive-ness.A counterintuitive approach is to tame aggressiveness by an agent that acts opposite to chemotherapeutic agents.Based on this strateg...
BACKGROUND There is an intimate crosstalk between cancer formation,dissemination,treatment response and the host immune system,with inducing tumour cell death the ultimate therapeutic goal for most anti-cancer treatme...
Calreticulin(CALR)is an endoplasmic reticulum(ER)-resident protein involved in a spectrum of cellular processes.In healthy cells,CALR operates as a chaperone and Ca^(2+)buffer to assist correct protein folding within ...
The National Marine Welfare Industry Research Project under contract No.201105012;the Guangdong Provincial Natural Science Foundation under contract No.S2011010000269;the Guangdong Marine Fishery Science and Technology Extension Project under contract No.A201308E02;the Guangdong Ocean University Scientific Research Start-up Fund for the Doctoral Program under contract No.R17066。
Calreticulin(CRT)is a highly conserved Ca2+-binding protein and chaperone in the endoplasmic reticulum,which mainly participates in adjusting calcium level and directing proper conformation of proteins.Here,we cloned ...