supported by the National Science and Technology Major Project of the Ministry of Science and Technology of China No.2022YFA1105800;the National Natural Science Foundation of China No.81970940(R.Y);Ten-thousand Talents Program QNBJ-2020(R.Y).
Bone defects caused by trauma or tumor led to high medical costs and poor life quality for patients.The exosomes,micro vesicles of 30-150 nm in diameter,derived from macrophages manipulated bone regeneration.However,t...
supported by The Biomechanics and Bio-materials Research Center at Indiana University-Purdue University Indianapolis,USA(No.2201-01);The NIH/Eunice Kennedy Shriver NICHD,USA(No.P50HD090215);The NIH/NCI Cancer Center Support Grant,USA(No.P30CA082709);The Tyler Trent Cancer Research Endowment for the Riley Hospital for Children IU-Health,USA;The Indiana University Grand ChallengeePrecision Health Initiative,USA.
Cancer cells tend to develop resistance to chemotherapy and enhance aggressive-ness.A counterintuitive approach is to tame aggressiveness by an agent that acts opposite to chemotherapeutic agents.Based on this strateg...
supported by the National Key Research and Development Program of China;Nos.2021YFC2 701800 and 2021YFC2 701805 (to QY);Open Research Fund of State Key Laboratory of Genetic Engineering;Fudan University;No.SKLGE-21 19 (to TXH and QY)
In Alzheimer’s disease,the transporter P-glycoprotein is responsible for the clearance of amyloid-βin the brain.Amyloid-βcorrelates with the sphingomyelin metabolism,and sphingomyelin participates in the regulation...
Supported by the Science and Technology Planning Project of Guangdong Province(No.201607010386);the Science and Technology Planning Project of Guangzhou(No.201504290959196)。
AIM: To investigate the role of moesin and its underlying signal transduction in retinal vascular damage induced by retinal ischemia-reperfusion(RIR) insult.METHODS: C57 BL/6 mice were subjected to continued ischemia ...