RETINAL

作品数：508被引量：805H指数：10
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Mesenchymal stem cell-derived small extracellular vesicles enhance the therapeutic effect of retinal progenitor cells in retinal degenerative disease rats
《Neural Regeneration Research》2026年第2期821-832,共12页Chunge Ren Min Chen Bangqi Ren Yuxiao Zeng Qiang Tan Qiyou Li Xue Zhang Yajie Fang Yixiao Zhou Weitao Zhang Fang Chen Baishijiao Bian Yong Liu 
supported by the National Natural Science Foundation of China,Nos.82271132(to YL),82101167(to BB);the Natural Science Foundation of Chongqing,Nos.CSTB2022NSCQ-MSX0020(to BB),cstc2019jcyj-msxmX0473(to FC).
Our previous study demonstrated that combined transplantation of bone marrow mesenchymal stem cells and retinal progenitor cells in rats has therapeutic effects on retinal degeneration that are superior to transplanta...
关键词：DIFFERENTIATION inflammation mesenchymal stem cells MICROGLIA migration rat retinal degeneration retinal progenitor cells small extracellular vesicles stem cell transplantation 
Bidirectional causality of physical exercise in retinal neuroprotection
《Neural Regeneration Research》2025年第12期3400-3415,共16页Stephen K.Agadagba Suk-yu Yau Ying Liang Kristine Dalton Benjamin Thompson 
supported by the InnoHK Initiative and the Hong Kong Special Administrative Region Government, China (to SYY)。
Physical exercise is recognized as an effective intervention to improve mood,physical performance,and general well-being.It achieves these benefits through cellular and molecular mechanisms that promote the release of...
关键词：age-related macular degeneration biomarkers diabetic retinopathy GLAUCOMA neuroprotective factors ocular diseases physical exercise retinal neuroprotection retinitis pigmentosa visual impairment 
AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis
《Neural Regeneration Research》2025年第8期2408-2419,共12页Ruiqi Qiu Mingzhu Yang Xiuxiu Jin Jingyang Liu Weiping Wang Xiaoli Zhang Jinfeng Han Bo Lei 
supported by the National Natural Science Foundation of China,Nos.82071008(to BL)and 82004001(to XJ);Medical Science and Technology Program of Health Commission of Henan Province,No.LHGJ20210072(to RQ);Science and Technology Department of Henan Province,No.212102310307(to XJ)。
Retinitis pigmentosa is a group of inherited diseases that lead to retinal degeneration and photoreceptor cell death.However,there is no effective treatment for retinitis pigmentosa caused by PDE6B mutation.Adeno-asso...
关键词：APOPTOSIS AAV2-PDE6B ERK1/2 gene therapy PHOTOTRANSDUCTION PROTEOMICS rd10 retinitis pigmentosa 
Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated weightlessness conditions
《Neural Regeneration Research》2025年第7期2116-2128,共13页Yuxue Mu Ning Zhang Dongyu Wei Guoqing Yang Lilingxuan Yao Xinyue Xu Yang Li Junhui Xue Zuoming Zhang Tao Chen 
supported by the Army Laboratory Animal Foundation of China,No.SYDW[2020]22(to TC);the Shaanxi Provincial Key R&D Plan General Project of China,No.2022SF-236(to YM);the National Natural Science Foundation of China,No.82202070(to TC)。
A microgravity environment has been shown to cause ocular damage and affect visual acuity,but the underlying mechanisms remain unclear.Therefore,we established an animal model of weightlessness via tail suspension to ...
关键词：glial fibrous acidic protein GLIOSIS Müller cells nerve growth factor neural differentiation neurodegeneration proteomic retinal degeneration retinal outer nuclear layer simulated weightlessness 
OCT predictors of retinal atrophy in neovascular agerelated macular degeneration treated with aflibercept
《International Journal of Ophthalmology(English edition)》2025年第4期648-655,共8页Oscar MGagliardi Ludovico Alisi Giacomo Visioli Federica Dini Giuseppe MAlbanese Stefano Scordari Marco Marenco Alessandro Lambiase Rosalia Giustolisi 
AIM:To identify optical coherence tomography(OCT)features present at the diagnosis of neovascular age-related macular degeneration(nAMD)that could predict retinal atrophy(RA)and visual performance in patients treated ...
关键词：neovascular age-related macular degeneration long-term prognosis optical coherence tomography OCT predictors retinal atrophy 
Vitreous surgery in treating complex retinal capillary hemangioma
《International Journal of Ophthalmology(English edition)》2025年第4期748-750,共3页Wan Cheng Wei-Ling Yan Shi-Yong Li Ke-Ran Li 
Supported by the Nanjing Science and Technology Development General Project(No.YKK23264).
Dear Editor,Retinal capillary hemangioma(RCH)is a benign vascular tumor that poses significant challenges due to its potential to cause vision impairment and retinal detachment(RD).We present a comprehensive case repo...
关键词：SURGERY HEMANGIOMA CAPILLARY 
Retinal Focus on Relationships between Diet-Induced, Advanced Glycation End Products and Supplemental Estradiol
《BIOCELL》2025年第3期349-354,共6页Nicholas T.Bello Bonnie L.Firestein Maribel Vazquez 
funded by a Life Sciences Alliance Pilot Seed Grant from the Rutgers-New Brunswick Office of the Vice Provost for Research,Grant Number OVPR-100(MV)。
Neurodegeneration of retinal tissue leads to progressive vision loss in millions of working-age adults each year.Metabolic alterations caused by modern diets that are high in fats and sugars contribute to the developm...
关键词：Muller glia endothelial cells HYPERGLYCEMIA diabetes 
Postnatal development of rat retina:a continuous observation and comparison between the organotypic retinal explant model and in vivo development
《Neural Regeneration Research》2025年第3期900-912,共13页Baoqi Hu Rui Wang Hanyue Zhang Xiou Wang Sijia Zhou Bo Ma Yan Luan Xin Wang Xinlin Chen Zhichao Zhang Qianyan Kang 
supported by the National Natural Science Foundation of China,Nos.81901156(to ZZ),82271200(to ZZ),82171308(to XC);the Fundamental Research Funds for the Central Universities,No.xzy012022035(to ZZ);the Natural Science Foundation of Shaanxi Province,Nos.2021JM-261(to QK),2023-YBSF-303(to ZZ);Traditional Chinese Medicine Project of Shaanxi Province,No.2019-ZZ-JC047(to QK)。
The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell cultures.However,the lack of systematic and contin...
关键词：bipolar cells differentiation in vivo microglia Müller glia organotypic retinal explant culture postnatal retina development proliferation retinal progenitor cells 
Changes in retinal capillary density in female with type 2 diabetes and gestational diabetes——an analysis based on OCTA technology
《International Journal of Ophthalmology(English edition)》2025年第3期435-448,共14页Jing Zhang Yao Yu Xian-Mei Zhou Xuan Liao Jin-Yu Hu Qian Ling Jie Zou Cheng Chen Liang-Qi He Hong Wei Xu Chen Yi-Xin Wang Yi Shao Rui-Man Li 
Supported by National Natural Science Foundation of China(No.82160195,No.82460203);The Science and Technology Innovation Program of Changde City(No.2023YD25).
AIM:To evaluate alterations in conjunctival vascular density(CVD)and macular capillary density(MCD)in female patients with type 2 diabetes mellitus(T2DM)and gestational diabetes mellitus(GDM)using optical coherence to...
关键词：diabetes optical coherence tomography angiography superficial retinal capillary plexus deep retinal capillary plexus retinal region segmentation method 
The cause of redetachment after vitrectomy with air tamponade for a cohort of 1715 patients with retinal detachment:an analysis of retinal breaks reopening被引量：1
《Eye and Vision》2025年第1期33-40,共8页Chuandi Zhou Chufeng Gu Bo Li Yujie Wang Yanan Hu Xinping She Ya Shi Mingming Ma Tao Sun Qinghua Qiu Ying Fan Fenge Chen Hong Wang Kun Liu Xiaodong Sun Xun Xu Zhi Zheng 
supported by the National Natural Science Foundation of China(Grant Nos.82271111 and 81770947);New Medical Technology in Key Disciplines of Shanghai General Hospital(Grant No.0000C1801000000201050);Shanghai Science and Technology Development Foundation(Grant No.22QA1407500);Shanghai Rising Stars of Medical Talent Youth Development Program(Grant No.SHWSRS[2022-65]);Clinical Research Innovation Plan of Shanghai General Hospital(Grant No.CTCCR-2021C01).
Background To investigate the prevalence and predictors of retinal breaks reopening after vitrectomy with air tamponade in rhegmatogenous retinal detachment(RRD).Methods A retrospective cohort study was conducted in S...
关键词：Retinal redetachment Air tamponade VITRECTOMY Retinal breaks reopening Postoperative restricted activities 
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