MITOGEN-ACTIVATED

作品数：58被引量：405H指数：11
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MicroRNA regulatory pattern in spinal cord ischemia-reperfusion injury被引量：10
《Neural Regeneration Research》2020年第11期2123-2130,共8页Zhi-Gang Liu Yin Li Jian-Hang Jiao Hao Long Zhuo-Yuan Xin Xiao-Yu Yang 
supported by the National Natural Science Foundation of China,No.81350013(to XYY)。
After spinal cord injury, dysregulated miRNAs appear and can participate in inflammatory responses, as well as the inhibition of apoptosis and axon regeneration through multiple pathways. However, the functions of miR...
关键词：gene REGULATORY networks microarray analysis MICRORNA miR-22-3p MITOGEN-ACTIVATED protein kinase signaling pathway nerve REGENERATION neural REGENERATION spinal CORD ISCHEMIA-REPERFUSION injury transcriptome 
Epigallocatechin gallate inhibits dimethylhydrazine-induced colorectal cancer in rats被引量：2
《World Journal of Gastroenterology》2020年第17期2064-2081,共18页Yu Wang Hei-Ying Jin Ming-Zhi Fang Xiao-Feng Wang Hao Chen Shu-Liang Huang De-Song Kong Min Li Xiu Zhang Yu Sun Shui-Ming Wang 
Supported by Nursing Advantage Discipline Construction Project Foundation of Jiangsu Province University,No.2019YSHL107;Nanjing Medical Science and Technique Development Foundation,No.NWQR-201705.
BACKGROUND Epigallocatechin gallate(EGCG)is a polyhydroxy phenolic compound extracted from tea and its antitumor effect has received widespread attention.We explored the inhibitory effect of EGCG on dimethylhydrazine(...
关键词：EPIGALLOCATECHIN gallate DIMETHYLHYDRAZINE Colorectal CANCER Aberrant CRYPT FOCI MITOGEN-ACTIVATED protein kinase The CANCER Genome Atlas 
Involvement of moesin phosphorylation in ischemia/reperfusion induced inner blood-retinal barrier dysfunction被引量：4
《International Journal of Ophthalmology(English edition)》2020年第4期545-551,共7页Jing Xu Qiong Liu Ming Ma Lin-Jiang Chen Jian Yu Ke Xiong Jing Wu 
Supported by the Science and Technology Planning Project of Guangdong Province(No.201607010386);the Science and Technology Planning Project of Guangzhou(No.201504290959196)。
AIM: To investigate the role of moesin and its underlying signal transduction in retinal vascular damage induced by retinal ischemia-reperfusion(RIR) insult.METHODS: C57 BL/6 mice were subjected to continued ischemia ...
关键词：RETINAL ISCHEMIA-REPERFUSION MOESIN p38 MITOGEN-ACTIVATED protein kinase INNER blood-retinal barrier mice 
Shenfu injection attenuates lipopolysaccharide-induced myocardial inflammation and apoptosis in rats被引量：17
《Chinese Journal of Natural Medicines》2020年第3期226-233,共8页CHEN Rui-Juan RUI Qing-Lin WANG Qiong TIAN Fang WU Jian KONG Xiang-Qing 
Shenfu injection(SFI), a Chinese medicinal product, shows potent efficacy in treating sepsis. The aim of the present study was to clarify the protective effects of SFI against lipopolysaccharide(LPS)-induced myocardia...
关键词：SHENFU injection LIPOPOLYSACCHARIDE Inflammation APOPTOSIS MITOGEN-ACTIVATED PROTEIN KINASE KINASE Extracellular regulated PROTEIN kinases 
Cloning,expression pattern,and potential role of MAPKp38 and NF-κBp65 in response to lipopolysaccharide in yellow catfish(Pelteobagrus fulvidraco)被引量：2
《Animal Nutrition》2019年第4期416-423,共8页Dan Shi Ye Zhao Lin Feng Yang Liu Wei-Dan Jiang Pei Wu Juan Zhao Jun Jiang Xiao-Qiu Zhou 
financially supported by the National Natural Science Foundation of China (31702362);the Applied Basic Research Programs of Science and Technology Commission Foundation of Sichuan Province,China (grant number 2015JY0067).
Mitogen-activated protein kinases(MAPK) and nuclear factor kappa B(NF-κB) pathways are considered to be two crucial intracellular signaling cascades in pro-inflammatory responses.In this study,we reported the coding ...
关键词：MITOGEN-ACTIVATED protein KINASES Nuclear factor kappa B LIPOPOLYSACCHARIDE Expression pattern Yellow CATFISH 
Reduced micro RNA 375 in colorectal cancer upregulates metadherin-mediated signaling被引量：4
《World Journal of Gastroenterology》2019年第44期6495-6507,共13页Seol-Hee Han Ji-Su Mo Won-Cheol Park Soo-Cheon Chae 
Supported by a grant from the National Research Foundation of Korea,No.2017R1A2B4004801
BACKGROUND The human microRNA 375(MIR375)is significantly downregulated in human colorectal cancer(CRC)and we have previously shown that MIR375 is a CRCassociated miRNA.The metadherin(MTDH)is a candidate target gene o...
关键词：MicroRNA 375 Metadherin MITOGEN-ACTIVATED protein KINASE ANGIOGENESIS Cell PROLIFERATION COLORECTAL cancer 
Extractive from Rauvolfia verticillata (Lour.) Baill. var. hainanensis Tsiang ameliorate ulcerative colitis in Dextran Sodium Sulfate-induced Mice via regulating the MAPK pathway
《Journal of Hainan Medical University》2019年第10期1-5,共5页Si-Qiong Li Lu-Jia Cui Xin-Pu Miao 
National Natural Science Foundation of China(No.81360603);Natural Science Foundation of Hainan Province(No.813215).
Objective: To investigate the effect and mechanism of Rauwolfia verticillata (Lour.) Baill. var. hainanensis Tsiang extract on mice with colitis induced by Dextran sulphate sodium (DSS). Methods: 80 BALB/C mice were r...
关键词：ULCER COLITIS RAUVOLFIA verticillata (Lour.) Baill. VAR. hainanensis Tsiang MITOGEN-ACTIVATED protein kinase 
Role of the IL-33/ST2/p38 signaling pathway in the immune response of corneal epithelial cells to Aspergillus fumigatus infection被引量：4
《International Journal of Ophthalmology(English edition)》2019年第4期549-556,共8页Jia You Jing Lin Yi-Fan Zhou Xu-Dong Peng Hong He Cui Li Guo-Qiang Zhu Xue-Qi Zhao Gui-Qiu Zhao 
Supported by the National Natural Science Foundation of China(No.81470609; No.81700800; No.81870632; No.81800800);Natural Science Foundation of Shandong Province(No.ZR2013HQ007; No.ZR2017MH008; No.ZR2017BH025);the Youth National Natural Science Foundation of China(No.81500695)
AIM: To investigate the expression of interleukin(IL)-33 in the cornea and human corneal epithelial cells(HCECs) exposed to Aspergillus fumigatus(A. fumigatus), and to determine the function of IL-33/ST2/p38 signaling...
关键词：ST2 INTERLEUKIN 33 Aspergillus FUMIGATUS CORNEA P38 MITOGEN-ACTIVATED protein kinase proliferation 
Efficacy of Lubeikangru formulation in mice with hyperplasia of the mammary glands induced by estrogen and progesterone被引量：9
《Journal of Traditional Chinese Medicine》2019年第2期174-180,共7页Sun Li Guo Donghui Liu Qian Xue Yanan Jiang Ning Zheng Hongxin 
Supported by Shenyang Science and Technology Plan(No.F14-199-4-00);Natural Science foundation of Liaoning Province(No.L20170540629);National Natural Science Foundation of China(No.81403396)
OBJECTIVE: To evaluate the protective effects of Lubeikangru formula(LF) on hyperplasia of the mammary glands(HMG) induced by estrogen and progesterone in mice.METHODS: Female mice were divided randomly into five grou...
关键词：HYPERPLASIA Mammary glands animal Hormones TAMOXIFEN MITOGEN-ACTIVATED protein KINASES Lubeikangru FORMULATION 
通便汤对STC大鼠模型结肠组织中PKA/MPKA信号通路的影响被引量：18
《中国实验方剂学杂志》2019年第5期135-142,共8页万叶敏 曾莉 钱海华 
国家自然科学基金面上项目(81573979)
目的:探讨通便汤对慢传输型便秘(slow transit constipation,STC)大鼠模型结肠组织中蛋白激酶A(protein kinase A,PKA)/丝裂原活化激酶(mitogen-activated protein kinase,MAPK)信号通路的影响及相关机制。方法:80只SD大鼠随机分为正常...
关键词：通便汤 慢传输型便秘 蛋白激酶A(protein kinase A PKA)/丝裂原活化激酶(mitogen-activated proteinkinase MAPK)信号通路 水通道蛋白3 4 
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