BACKGROUND The incidence of oesophageal adenocarcinoma(OAC)has been reported to be increasing in many countries.Alongside this trend,an increase in incidence of early-onset OAC,defined as OAC in adults aged under 50 y...
supported by the National Key Research and Development Program of China(2022YFC2009600,2022YFC2009601)to Dr.Hanping Shi;The Jiangxi Province Science Foundation for Youths(20161BAB215187)to Li Deng。
The characteristics of early-onset(onset age<50 years)and later-onset(onset age≥50 years)cancers differ significantly.Identifying novel risk factors for both types of cancer is crucial for increasing awareness of can...
supported by the National Natural Science Foundation of China(Nos.82202837,81730016,and 81972761)
The incidence of early-onset gastric cancer(EOGC)is consistently increasing,and its etiology is notably complex.This increase may be attributed to distinctive factors that differ from those associated with late-onset ...
This article discusses a recently published case report on a rare instance of type IV appendiceal intussusception with a concurrent mucinous adenocarcinoma of the cecum in a young individual.The report highlights chal...
funded by the Chinese Academy of Medical Science Innovation Fund for Medical Science(grant number:2022-I2M-1-0031);the National Natural Science Foundation of China(grant number:82173606);supported by the Beijing Nova Program of Science and Technology(grant number:20230484397);the Na-tional Natural Science Foundation of China(grant number:82273726).
Background: The incidence of early-onset colorectal cancer (EOCRC), which exhibits differential clinical, patho- logical, and molecular features compared to late-onset CRC (LOCRC), is rising globally. The potential di...
funded by the National Natural Science Foundation of China(Grant No.82301639 to Bin Li,Grant No.82171441 to Xu-Qin Chen,and Grant No.82201609 to Jie Wang).
The ARHGAP4 gene(OMIM*300,023),also known as Rho GTPase activating protein 4,encodes a protein that has an essential role in the regulation of small GTP-binding.ARHGAP4 message RNA(mRNA)is highly expressed during the ...
Supported by the Oregon Health&Sciences(OHSU)Institutional Review Board,No.STUDY00026428.
BACKGROUND The incidence of early-onset colorectal cancer(EO-CRC)is rising in the United States,and is often diagnosed at advanced stages.Low serum ferritin is often incidentally discovered in young adults,however,the...
funded by the National Natural Science Foundation of China (Grant No. 82273721);the National Natural Science Foundation of China (Grant No. 81974492);the Capital’s Funds for Health Improvement and Research Conflict of interest statement (Grant No. 2024-1G-4023);CAMS Innovation Fund for Medical Sciences (CIFMS)(Grant No. 2021-I2M-C&T-B-049)。
Objective: The burden of gastric cancer(GC) across different age groups needs updating. We determined the GC global, regional, and national burden profiles and changes in incidence for 3 sequential 5-year intervals fr...
supported by the National Science Fund for Distinguished Young Scholars(81725005);the National Natural Science Foundation Regional Innovation and Development Joint Fund(U20A6005);the National Natural Science Foundation of China(82151315 and 62176129);the National Key Research and Development Program(2022YFC2405605);the Jiangsu Provincial Key Research and Development Program(BE2021617 and BE2022160);the Key Project supported by Medical Science and Technology Development Foundation,Jiangsu Commission of Health(ZD2021026);the Jiangsu Funding Program for Excellent Postdoctoral Talent(2023ZB818);the Postdoctoral Research Project of Changzhou Medical Center,Nanjing Medical University(CMCP202305).
Early-onset mental disorders are associated with disrupted neurodevelopmental processes during adolescence.The methylazoxymethanol acetate(MAM)animal model,in which disruption in neurodevelopmental processes is induce...
Colorectal cancer used to be a common disease among middle-aged and elderly people.In recent years,the incidence of colorectal cancer(Early-onset colorectal cancer,EOCRC)under 50 years old has increased year by year.D...