NUCLEUS

作品数:813被引量:803H指数:11
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相关机构:华中科技大学重庆邮电大学中国科学院解放军信息工程大学更多>>
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Integrating spatial transcriptomics and single-nucleus RNA-seq revealed the specific inhibitory effects of TGF-β on intramuscular fat deposition
《Science China(Life Sciences)》2025年第3期746-763,共18页Xiaoyu Wang Chuchu Chen Chenggan Li Xiaochang Chen Rong Xu Meilin Chen Yongpeng Li Yihao Liu Xiaohong Liu Yaosheng Chen Delin Mo 
supported by the National Natural Science Foundation of China(323B2058);Selection and Breeding of New Local Pig Breeds and Promotion of Industrialization(2022-440000-43010101-9501);Selection and Breeding of Guangdong Small-ear Spotted Pig(2022-440000-4301030202-9510);China Agriculture Research System(CASR-35);the Key Scientific Research Project of Education Department of Shaanxi(22JS033).
Intramuscular fat(IMF)is a complex adipose tissue within skeletal muscle,appearing specially tissue heterogeneous,and the factors influencing its formation remain unclear.In conditions such as diabetes,aging,and muscl...
关键词:intramuscular fat muscle atrophy spatial transcriptome single-nucleus RNA-seq TGF-Β 
Developmental dynamics of the single nucleus regulatory landscape of pig hippocampus
《Science China(Life Sciences)》2023年第11期2614-2628,共15页Siyu Yang Dong Chen Lei Xie Xiaoxiao Zou Yanyuan Xiao Lin Rao Tianxiong Yao Qing Zhang Liping Cai Fei Huang Bin Yang Lusheng Huang 
supported by the National Natural Science Foundation of China(32160781).
The hippocampus is a brain region associated with memory,learning and spatial navigation,its aging-related dysfunction is a common sign of Alzheimer’s disease.Pig is a good model for human neurodegenerative disease,b...
关键词:HIPPOCAMPUS PIG chromatin accessibility gene expression NUCLEI accessible chromatin regions development 
AoATG5 plays pleiotropic roles in vegetative growth,cell nucleus development,conidiation,and virulence in the nematode-trapping fungus Arthrobotrys oligospora被引量:2
《Science China(Life Sciences)》2022年第2期412-425,共14页Duanxu Zhou Yingmei Zhu Na Bai Le Yang Meihua Xie Jiangliu Yang Meichen Zhu Ke-Qin Zhang Jinkui Yang 
the National Natural Science Foundation of China(31960556 and U1402265);the Applied Basic Research Foundation of Yunnan Province(202001BB050004);the National Basic Research Program of China(2013CB127503)。
Autophagy is an evolutionarily conserved process in eukaryotes,which is regulated by autophagy-related genes(ATGs).Arthrobotrys oligospora is a representative species of nematode-trapping(NT)fungi that can produce spe...
关键词:Arthrobotrys oligospora autophagy-related gene AoATG5 phenotypic traits transcriptome analysis SPORULATION cell nucleus development 
A non-structural protein encoded by Rice Dwarf Virus targets to the nucleus and chloroplast and inhibits local RNA silencing
《Science China(Life Sciences)》2020年第11期1703-1713,共11页Feng Gao Shanshan Zhao Shuzhen Men Zhensheng Kang Jian Hong Chunhong Wei Wei Hong Yi Li 
supported by grants from CARS-01-06 to X.H.X., Transgenic Research Program (2016ZX08010001);the National Natural Science Foundation of China (31530062)。
RNA silencing is a potent antiviral mechanism in plants and animals. As a counter-defense, many viruses studied to date encode one or more viral suppressors of RNA silencing(VSR). In the latter case, how different VSR...
关键词:Rice dwarf virus Pns11 RNA silencing suppressor nuclear and chloroplastic localization 
The 3D organization of genome in the nucleus: from the nucleosome to the 4D nucleome被引量:1
《Science China(Life Sciences)》2020年第6期791-794,共4页Guohong Li 
The genetic information,stored in the linear sequences of DNA,encodes all of the genes that a living organism uses to produce proteins and RNAs essential for various cellular functions.In eukaryotes,however,genomic DN...
关键词:The 3D organization of genome in the nucleus from the nucleosome to the 4D nucleome 
An optical brain-to-brain interface supports rapid information transmission for precise locomotion control被引量:6
《Science China(Life Sciences)》2020年第6期875-885,共11页Lihui Lu Ruiyu Wang Minmin Luo 
Ministry of Science and Technology of China (2015BAI08B02);the National Natural Science Foundation of China (91432114 and 91632302);the Beijing Municipal Government。
Brain-to-brain interfaces(BtBIs) hold exciting potentials for direct communication between individual brains. However,technical challenges often limit their performance in rapid information transfer. Here, we demonstr...
关键词:brain-to-brain interface locomotion nucleus incertus fiber photometry OPTOGENETICS support vector machine(SVM)classifier 
Visualizing the microtubule-associated protein tau in the nucleus被引量:11
《Science China(Life Sciences)》2014年第4期422-431,共10页LU Jing LI Ting HE RongQiao BARTLETT Perry F GTZ Jürgen 
supported by the Estate of Dr.Clem Jones AO and the Aus-tralia-China Joint Laboratory of Neuroscience and Cognition,as well as grants from the Australian Research Council;the National Health and Medical Research Council of Australia to Jürgen Gtz
Although tau is mainly known as an axonal microtubule-associated protein,many studies indicate that it is not restricted to this subcellular compartment.Assessing tau’s subcellular distribution,however,is not trivial...
关键词:Alzheimer's disease FRACTIONATION microtubule-associated protein NEUROBLASTOMA NUCLEUS PHOSPHORYLATION TAU 
Simulation study on the efficiencies of MOET nucleus breeding schemes applying marker assisted selection in dairy cattle被引量:2
《Science China(Life Sciences)》2009年第3期296-306,共11页LUO WeiZhen,WANG YaChun & ZHANG Yuan Department of Animal Genetics & Breeding,College of Animal Science and Technology,China Agricultural University,Beijing 100094,China 
Supported by Key Project for Introducing Advanced International Agriculture Science&Technologies (Grant No.2006-G48);the National Key Basic Research and Development Program of China (Grant No.2006CB102107);National Key Technology Research and Development Program of China (Grant No.2006BAD04A01)
Advantages of breeding schemes using genetic marker information and/or multiple ovulation and embryo transfer(MOET) technology over the traditional approach were extensively evaluated through simulation.Milk yield was...
关键词:DAIRY CATTLE marker-assisted SELECTION two-stage SELECTION MOET QTL 
Infusion of methylphenidate into the basolateral nucleus of amygdala or anterior cingulate cortex enhances fear memory consolidation in rats
《Science China(Life Sciences)》2008年第9期808-813,共6页ZHENG XinLing LIU Fang WU XingWen LI BaoMing 
Supported by the Ministry of Science and Technology of China(Grant Nos.2006CB500807 and 2006AA02Z199);the Ministry of Education of China(Program for Changjiang Scholars and Innovative Research Team in University);the National Natural Science Foundation of China(Grant Nos.30225023,30430240 and 30611120530)
The psychostimulant methylphenidate (MPD; also called Ritalin) is a blocker of dopamine and norepi-nephrine transporter. It has been clinically used for treatment of Attention Deficit and Hyperactivity Disorder (ADHD)...
关键词:METHYLPHENIDATE RITALIN basolateral nucleus of amygdala anterior cingulate cortex fear memory rat 
Effect of lesion of nucleus robustus archistriatalis on call in bramble finch (Fringilla montifringilla)被引量:3
《Science China(Life Sciences)》2001年第5期479-488,共10页蒋锦昌 李东风 李杰 杨新宇 
the National Natural Science Foundation of China (Grant No. 39570195) and Outstanding Youth Foundation of Ministry of Education of China.
The lesion of nucleus robustus archistriatalis (RA) has no effect on normal short calls in the bramble finch, but affects significantly the temporal and acoustic features of learned long calls.It causes the principal ...
关键词:bramble finch nucleus robustus archistriatalis (RA) vocal control pattern. 
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