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Transcriptome and proteome analysis reveals the characteristics of carbon metabolism in the mycelial development of Gomphus purpuraceus
《Food Science and Human Wellness》2025年第3期941-957,共17页Yangyang Geng Shixin Zhang Yana Liu Likang Qin 
the Science and Technology Program of Guizhou Province(2022-General 112);the Major Scientific and Technological Special Project of Guizhou Province(20193006-2);the Regional Fund Project of National Natural Science Foundation of China(32460795)。
Gomphus purpuraceus is an ancient wild edible mushroom.However,the niche and lignocellulose degradation system of G.purpuraceus have remained cryptic.In the current study,transcriptome and proteome sequencing of G.pur...
关键词：Gomphus purpuraceus Multi-omics CAZymes Lignocellulose decomposition FUMONISINS 
Multi-omics analysis reveals the epitranscriptomic and proteomic regulation network of tomato in low-temperature stress response
《Horticultural Plant Journal》2025年第2期758-773,共16页Na Wang Yanting Li Tianli Guo Libo Jiang 
financially supported by the National Natural Science Foundation of China(Grant Nos.32202518 and 32070601);Shandong University of Technology PhD Start-up Fund(418097)。
Tomato(Solanum lycopersicum)is an extensively cultivated vegetable,and its growth and fruit quality can be significantly impaired by low temperatures.The widespread presence of N^(6)-methyladenosine(m^(6)A)modificatio...
关键词：Epitranscriptome m^(6)A methylation PROTEOME Alternative polyadenylation Low temperature TOMATO 
Systematical identification of regulatory GPCRs by single-cell trajectory inference reveals the role of ADGRD1 and GPR39 in adipogenesis
《Science China(Life Sciences)》2025年第4期1057-1072,共16页Chuan Ye Xuemei Wang Jun Lin Chenyang Wu Yuhua Gao Chenghao Guo Yunxi Liao Ziyan Rao Shaodong Huang Weixuan Chen Ying Huang Jinpeng Sun Dongyu Zhao Changtao Jiang 
supported by the National Natural Science Foundation of China(32270603,31925021,82130022,92357305,82341226,32271232);the National Key Research and Development Program of China(2021YFF1201100,2018YFA0800701);the Fundamental Research Funds for the Central Universities(BMU2021YJ057)。
Adipogenesis is the healthy expansion of white adipose tissue(WAT),serving as a compensatory response to maintain metabolic homeostasis in the presence of excess energy in the body.Therefore,the identification of nove...
关键词：ADIPOGENESIS GPCRS trajectory inference 
Transcriptome study reveals tick immune genes restrict Babesia microti infection
《Insect Science》2025年第2期457-470,共14页Tingting Feng Hao Tong Feihu Zhang Qianqian Zhang Heng Zhang Xia Zhou Hang Ruan Qihan Wu Jianfeng Dai 
supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions,National Natural Science Foundation of China(32170142,81971917,81271792,81471571);Jiangsu Natural Science Foundation(BK20211310),and funding from Suzhou International Joint Laboratory for Diagnosis and Treatment of Brain Diseases.
A systems biology approach was employed to gain insight into tick biology and interactions between vectors and pathogens.Haemaphysalis longicornis serves as one of the primary vectors of Babesia microti,significantly ...
关键词：BABESIA immune signaling pathway TICK TRANSCRIPTOME vector-pathogen interactions 
Gene expression analysis in subcutaneous adipose tissue reveals a predominant influence of IncRNAs during growth
《Genes & Diseases》2025年第2期125-128,共4页Federica Reyy Letizia Messa Clarissa Berardao Alessia Mauri Gianvincenzo Zuccotti Cristina Cereda Stephana Carelli 
The adipose tissue is a crucial energy reservoir that can undergo significant changes during aging,impacting the pathogenesis of metabolic disorders,including obesity.1 Obesity affects individuals of all ages,with dif...
关键词：OBESITY PATHOGENESIS predominant 
Metabolomic reveals the inhibition mechanism of proline on hexanal production in chicken meat
《Food Science and Human Wellness》2025年第2期662-670,共9页Huanxian Cui Yuxi Jin Yanke Wang Xiaoya Yuan Li Liu Jie Wen Guiping Zhao 
funded by grants from the State Key Laboratory of Animal Nutrition(2004DA125184G2109);Basic Research from Chinese Academy of Agricultural Sciences(Y2019XK06);the Agricultural Science and Technology Innovation Program(ASTIP-IAS04);the Earmarked Fund for Modern Agro-Industry Technology Research System(CARS-41)。
Hexanal contributes significantly to meat flavor.The aim of this study was to identify the metabolic pathways of hexanal formation in chicken meat.We found 32 metabolites associated with hexanal content in chicken mea...
关键词：FLAVOR Amino acids Fatty acids Negative regulation Pyrimidine metabolism pathway 
Untargeted metabolomics combined with 16S rRNA sequencing reveals the characteristics of intestinal metabolism and gut microbiota in hazelnut Cor a 14-allergic BALB/c mice
《Food Science and Human Wellness》2025年第2期692-705,共14页Chen Chen Kaiyu Mu Qiang Xie Wentong Xue 
supported by the National Key Research and Development Program of China(2019YFC1605000)。
Cor a 14 is one of the most vital allergens in hazelnuts.However,the features of intestinal metabolites and microbiota associated with Cor a 14-induced allergy remain unclear.In this study,we established a hazelnut Co...
关键词：Food allergy Hazelnuts Cor a 14 Untargeted metabolomics Gut microbiota L-TRYPTOPHAN 
Multi-omics reveals the associations among the fecal metabolome,intestinal bacteria,and serum indicators in patients with hepatocellular carcinoma
《World Journal of Gastroenterology》2025年第15期109-130,共22页Jing Feng Jun-Ping Wang Jian-Ran Hu Ping Li Pin Lv Hu-Cheng He Xiao-Wei Cheng Zheng Cao Jia-Jing Han Qiang Wang Qian Su Li-Xin Liu 
Supported by the Department of Science and Technology of Shanxi Province,No.20210302124369;the Health Commission of Shanxi Province,No.2021116;Shanxi Administration of Traditional Chinese Medicine,No.2024ZYY2C054.
BACKGROUND Hepatocellular carcinoma(HCC),the predominant form of primary liver cancer,is a key contributor to cancer-related deaths globally.However,HCC diagnosis solely based on blood biochemical markers lacks both s...
关键词：Hepatocellular carcinoma Fecal metabolomics Intestinal bacteria Correlation analysis Non-targeted liquid chromatography-mass spectrometry 
TMT-based quantitative proteomics reveals the potential mechanism of the FufangMuji Granules in carbon tetrachloride-induced liver injury
《Traditional Medicine Research》2025年第4期21-30,共10页Lei Men Ya-Qi Shi Xin-Yue Wang Ke-Ke Li Zhong-Yu Li Chun-Bin Li Xiao-Jie Gong 
National Natural Science Foundation of China(82104532 and 82173913);Joint Program(Applied Basic Research Project)of Liaoning Provincial Science and Technology Program(2023JH2/101700074);High-level Talent Innovation Support Program of Dalian(2021RD10);Fundamental Research Funds for the Central Universities(2023-SWGC-0101)。
Background:Fufang Muji Granules is a traditional Chinese medicine of the Manchu ethnic group and is thought to treat hepatitis and liver injury by inhibiting the elevation of alpha-fetoprotein.Methods:In this investig...
关键词：PROTEOMICS Fufang Muji Granules liver injury traditional Chinese medicine 
Molecular Diagnosis of Sexually Transmitted Infection Reveals a High Frequency of Neisseria gonorrhoeae Infection among Male Urethritis Patients and Highlights the Usefulness of Molecular Testing for Clinical Diagnosis in Burkina Faso
《American Journal of Molecular Biology》2025年第1期123-134,共12页Michel Kiréopori Gomgnimbou Azouman Da Louis Robert W. Belem Kobo Gnada Karlhis Raymond Yao Arnaud Quetin Sanou Armel Moumouni Sanou Soufiane Sanou Dramane Kania 
Sexually transmitted infections (STIs) represent a public health problem due to their high prevalence worldwide and the emergence of multidrug resistance of responsible microorganisms. Medical laboratory diagnosis of ...
关键词：Molecular Diagnostic Methods PATHOGENS Sexually Transmitted Infection URETHRITIS Burkina Faso 
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