funded by JSPS KAKENHI Grant Numbers JP26290015 and JP21H02655(to TK)from Ministry of Education,Culture,Sports,Science,and Technology of Japan(MEXT)。
Cell adhesion plays pivotal roles in the morphogenesis of multicellular organisms.Epithelial cells form several types of cell-to-cell adhesion,including zonula occludens(tight junctions),zonula adhaerens(adherens junc...
supported by the National Natural Science Foundation of China(92354301,32222022,32300569,and 92054104);R&D Program of Guangzhou National Laboratory(GZNL2023A03004);Key Research and Development Program,the Ministry of Science and Technology of China(2022YFC2303502 and 2021YFC2300204);the Natural Science Foundation of Shanghai(23ZR1470900);Youth Innovation Promotion Association,Chinese Academy of Sciences.
The dynamic remodeling of the cytoskeletal network of vimentin intermediate filaments supports various cellular functions,including cell morphology,elasticity,migration,organelle localization,and resistance against me...
Background:Living cells need to undergo subtle shape adaptations in response to the topography of their substrates.These shape changes are mainly determined by reorganization of their internal cytoskeleton,with a majo...
supported by the National Natural Science Foundation of China (31970198 and 31900239);the Natural Science Foundation of Henan Province (202300410230).
Plant root hairs are essential for mineral and water absorption,which possess sophisticated sensory mechanisms to allow them to respond to different environmental signals.Ammonium(NH^(+))is a major form of nitrogen in...
This work was supported,in part,by the National Institute of Diabetes and Digestive and Kidney Disease(Grant No.P30 DK123704);the National Institute of General Medical Sciences(Grant No.P20 GM 130457).
Hepatic stellate cells(HSCs)are the primary effector cells in liver fibrosis.In the normal liver,HSCs serve as the primary vitamin A storage cells in the body and retain a“quiescent”phenotype.However,after liver inj...
supported through the Australian National Health&Medical Research Council(NHMRC APP1163249).
Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disease characterized by selective,early degeneration of motor neurons in the brain and spinal cord.Motor neurons have long axonal projections,which...
This work was supported by the National Natural Science Foundation of China(31661143035,31770881,and 32071288);the National Basic Research Program of China(2017YFA0504400)to J.H.
Accumulating evidence indicates that the alternative splicing program undergoes extensive changes during cancer develop-ment and progression.The RNA-binding protein QKI-5 is frequently downregulated and exhibits anti-...
Department of Defense BC150678P1(WRT),NIH AR069943-01(WRT),NIH AR068332(US),and Department of Defense BC150678(TAG).
Exercise benefits the musculoskeletal system and reduces the effects of cancer.The effects of exercise are multifactorial,where metabolic changes and tissue adaptation influence outcomes.Mechanical signals,a principal...
Supported by EFOP-3.6.3-VEKOP-16-2017-00009 and GINOP-2.3.2-15-2016-00036 to University of Pécs Medical School;EFOP-3.6.1-16-2016-00004 project;The Higher Education Institutional Excellence Programme of the Ministry for Innovation and Technology in Hungary,within the framework of the 5.thematic programme of the University of Pécs。
AIM:To study the effect of mechanical stress on the cytoskeleton in lens epithelial cells following conventional phacoemulsification surgery(CPS)and femtosecond laserassisted cataract surgery(FLACS).METHODS:The cytosk...