BACKGROUND Adenoviruses pose a serious health risk particularly in the absence of any clinically approved treatment.As adenoviral infections are quite frequent and recent outbreaks manifest more virulent variant strai...
Supported by Taipei Veterans General Hospital in Taiwan,No.V106C-012,No.V107C-087,and No.V109C-018;and Ministry of Science and Technology in Taiwan,No.MOST106-2314-B-075-023,No.MOST107-2314-B-010-023,and No.MOST107-2314-B-075-021.
BACKGROUND Parkinson’s disease(PD)is a neurological disorder characterized by the progressive loss of midbrain dopamine(DA)neurons.Bone marrow mesenchymal stem cells(BMSCs)can differentiate into multiple cell types i...
AIM: To evaluate the clinical characteristics of adenoviral keratoconjunctivitis, the management modalities, as well as the incidence of subepithelial corneal infiltrates(SEI).METHODS: Patients with characteristic cli...
supported by grants, R01-AR063631 (JPS) and F31-AR064673 (AMB), from the National Institutes of Health/National Institute for Arthritis, Musculoskeletal and Skin Diseases
We report here a method for the use of poly-L-lysine (PLL) to markedly improve the adenoviral transduction efficiency of primary murine osteoblasts and bone marrow stromal cells (BMSCs) in culture and in situ, whi...
Dear Sir,Iam Yonca A.Akova,MD-from the Department of Ophthalmology,Bayindir Kavaklidere Hospital,Turkey.I wrote this letter to evaluate the efficacy of 0.05%topical cyclosporine A(CsA)eye drops(Restasis Allergan,Ir...
Supported by National Natural Science Foundation of China.No.81272687;Zhejiang Provincial Public Welfare Technology Application Research Projects,No.2014C33275;Zhejiang Provincial Natural Science Foundation of China,No.LZ13H160004;the Grant for 521 Talent Project of Zhejiang Sci-Tech University,Hangzhou,China
Human hepatocellular carcinoma(HCC)heavily endangers human heath worldwide.HCC is one of most frequent cancers in China because patients with liver disease,such as chronic hepatitis,have the highest cancer susceptibil...
Objective To observe the impact of PDE5shRNA on cardiac remodeling and heart function following myocardial infarction in mice.Methods Myocardial infarction(MI)was induced in mice by left coronary artery ligation.Mice ...
Vaccines are an integral part of veterinary disease prevention. However there are still a significant number of veterinary diseases for which vaccines do not currently exist or where currently available vaccines do no...
Supported by NIH Grants 1R21CA129801(to Arbab AS);R01CA122031(to Arbab AS)
AIM:To determine whether endothelial progenitor cells(EPCs)can be used as delivery vehicle for adenoviral vectors and imaging probes for gene therapy in glioblastoma.METHODS:To use cord blood derived EPCs as delivery ...
Background and objective Once the malignant pleural or peritoneal effusion is developed it is difficult to control.This report presents a new method for controlling the malignant effusions.Methods Forty-eight patients...