supported by CRI project(no.2018R1A3B1052702;J.S.K.)from the National Research Foundation of Korea(NRF);by the China Scholarship Fund(CSC no.201907030009;L.Y.);by the Interne Fondsen KU Leuven/Internal Funds KU Leuven(STG/19/029;P.V.).
The nucleolus,the locus of ribosome biogenesis,was found to be the predominant intracellular target of a new fluorescent probe,V-P1.In solution,the probe demonstrated both a selectivity to RNA G-quadruplexes and a sen...
Dear Editor,Three polyamines,putrescine,spermidine,and spermine,are tightly regulated and are synthesized from arginine,ornithine,and methionine(Miller-Fleming et al.,2015;Figure 1A).Polyamine levels are increased in ...
In a recent paper published in Cell Research,Wang et al.identify a nucleolar-localized long noncoding RNA(lncRNA),LETN(lncRNA essential for tumor cell proliferation via NPM1)and depict a mutually dependent NPM1–LETN ...
the grants from the National Natural Science Foundation of China (No.31501911);the Project funded by China Postdoctoral Science Foundation (No.2017M611257);the National Program on Key Basic Research Project (973 Program)(No.2013CB835304);the General Scientific Research Foundation of Liaoning Educational Committee (No.L2015293);the Youth Scientific Research Project of Liaoning Normal University (No.LS2014L008).
Nucleolin was first described in 1973 as a protein involved in ribosome biogenesis and in DNA and RNA metabolism.It is a wellknown major non-ribosomal protein in the nucleolus,and is mainly distributed in the dense fi...
Supported by The National Natural Science Foundation of China,No.30772534;Science and Technology Program Fund of Zhejiang Province,No.2006C33028;the Huzhou Natural Science Foundation,No.2004SZX07-11
Midkine(MK) is a heparin-binding growth factor with its gene first identified in embryonal carcinoma cells at early stages of retinoic acid-induced differentiation. MK is frequently and highly expressed in a variety o...
supported by grants from the Special Fund for Major State Basic Research Project(No.G1999055901);National Natural Sciences Foundation of China(No.30240019);National High Technology Research and Technology of China(No.2001AA221131);State Ministry of Science and Technology Program(No.2002BA711A011.
Variable Charge X/Y (VCX/Y) is a human testis-specific gene family that localized on X and Y chromosomes. In this study, VCY protein was expressed in E. coli in the form of glutathione-S-transferase (GST) fusion prote...
Project supported by the National Natural Science Foundation of China (Grant No. 39730300).
A novel intronic small nucleolar RNA (snoRNA), termed Z25, was identified from mammals by computer analysis and experimental sequence methods. Z25 is a 69 nucleotides long RNA containing typical boxC/D motifs, termina...
The effects of different concentrations of Zn ̄(2+)ion on root growth,cell division,and nucleoli of Allium cepa were studied. The test Zn ̄(2+) ion concentration was made up from zinc sulphate (ZnSO4. 7H2O) ranging fr...