CHEMOKINES

作品数：131被引量：681H指数：14
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Caffeic acid-vanadium nanozymes treat skin flap ischemia-reperfusion injury through macrophage reprogramming and the upregulation of X-linked inhibitors of apoptotic proteins
《Acta Pharmaceutica Sinica B》2025年第1期592-610,共19页Xinyu Zhao Jie Shan Hanying Qian Xu Jin Yiwei Sun Jianghao Xing Qingrong Li Xu-Lin Chen Xianwen Wang 
supported by the National Natural Science Foundation of China(Grant Nos.82172204,82372552 and 82372517);the Anhui Key Research and Development Plan(Grant No.202104j07020027,China);the Excellent Youth of Natural Science Research Projects in Anhui Province Universities(2023AH030060);the Basic and Clinical Cooperative Research and Promotion Program of Anhui Medical University(No.2021xkjT028,China);the Research Fund of Anhui Institute of Translational Medicine(2022zhyx-C01,China);the Scientific Research Programme for Higher Education Institutions in Anhui Province(2023AH040371,China).
Ischemia-reperfusion(I/R)injury following skin flap transplantation is a critical factor leading to flap necrosis and transplant failure.Antagonizing inflammatory responses and oxidative stress are regarded as crucial...
关键词：Caffeic acid-vanadium Nanozymes Skin flap ISCHEMIA-REPERFUSION Oxidative stress Inflammation CHEMOKINES Apoptosis 
Kynurenine-AhR reduces T-cell infiltration and induces a delayed T-cell immune response by suppressing the STAT1-CXCL9/CXCL10 axis in tuberculosis
《Cellular & Molecular Immunology》2024年第12期1426-1440,共15页Xin Liu Mengjie Yang Ping Xu Mingwei Du Shanshan Li Jin Shi Qiang Li Jinfeng Yuan Yu Pang 
supported by the National Key Research and Development Program of China(2022YFC2302901);the National Natural Science Foundation of China(82272346,82072243,82202530);the Sponsored by Beijing Nova Program(20220484169,20230484295);the Provincial Key Research and Development Program of Jiangsu in Social Development(BE2023718).
Tuberculosis,caused by Mycobacterium tuberculosis(Mtb),is a critical global health issue that is complicated by the ability of the pathogen to delay the host’s T-cell immune response.This delay in T-cell recruitment ...
关键词：Mycobacterium tuberculosis Tryptophan metabolism IDO1 IMMUNOSUPPRESSION CHEMOKINES 
Investigation of parasite genetic variation and systemic immune responses in patients presenting with different clinical presentations of cutaneous leishmaniasis caused by Leishmania aethiopica
《Infectious Diseases of Poverty》2024年第5期104-105,共2页Endalew Yizengaw Yegnasew Takele Susanne Franssen Bizuayehu Gashaw Mulat Yimer Emebet Adem Endalkachew Nibret Gizachew Yismaw Edward Cruz Cervera Kefale Ejigu Dessalegn Tamiru Abaineh Munshea Ingrid Müller Richard Weller James A.Cotton Pascale Kropf 
Background Cutaneous leishmaniasis(CL)is a neglected tropical skin disease,caused by the protozoan parasite Leishmania.In Ethiopia,CL is mainly caused by Leishmania aethiopica and can present in different clinical for...
关键词：Cutaneous leishmaniasis Leishmania aethiopica Genetics CYTOKINES CHEMOKINES Plasma 
Mental disorders after myocardial infarction:potential mediator role for chemokines in heart-brain interaction?
《Journal of Geriatric Cardiology》2024年第9期913-926,共14页Parth Patel Feiyan Yang Dumitru A.Iacobas Lei Xi 
Acute myocardial infarction(MI)remains one of the leading causes of mortality and morbidity in the global communities.A prevailing topic that has attracted increasing attentions over the past few decades is the so-cal...
关键词：CHEMOKINE DISORDERS POTENTIAL 
The secondary injury cascade after spinal cord injury:an analysis of local cytokine/chemokine regulation被引量：3
《Neural Regeneration Research》2024年第6期1308-1317,共10页Daniel J.Hellenbrand Charles M.Quinn Zachariah J.Piper Ryan T.Elder Raveena R.Mishra Taylor L.Marti Phoebe M.Omuro Rylie M.Roddick Jae Sung Lee William L.Murphy Amgad S.Hanna 
supported by the National Institutes of Health;No.R56 NS117935(to ASH and WLM);funded by Institutional Clinical and Translational Science Award;No.UL1 TR002373。
After spinal cord injury,there is an extensive infiltration of immune cells,which exacerbates the injury and leads to further neural degeneration.Therefore,a major aim of current research involves targeting the immune...
关键词：ASTROCYTES CHEMOKINES cytokines inflammation macrophages MICROGLIA secondary damage spinal cord injury 
Advances in chemokines of teleost fish species
《Aquaculture and Fisheries》2024年第2期115-125,共11页Hongsen Xu Fuguo Liu 
supported by the Natural Science Foundation of Hubei Province(grant no.2021CFB265);Engineering Research Center of Feed Protein Resources on Agricultural By-products,Ministry of Education(grant no.DKXY2020015);Key Laboratory of Special Aquatic Formula Feed(grant no.TMKJZ1706 and TMKJZ1912).
In mammals,chemokines are a superfamily of cytokines that regulate cell migration or exert direct antimicrobial activity.The presence and organization of four invariant cysteine residues within the mature protein sequ...
关键词：CHEMOKINES TELEOST 
Dual-directional regulation of spinal cord injury and the gut microbiota被引量：3
《Neural Regeneration Research》2024年第3期548-556,共9页Yinjie Cui Jingyi Liu Xiao Lei Shuwen Liu Haixia Chen Zhijian Wei Hongru Li Yuan Yang Chenguang Zheng Zhongzheng Li 
supported by the National Natural Science Foundation of China,Nos.82105019(to YC),82271218(to CZ);Natural Science Foundation of Tianjin Municipality Foundation,No.20JCZDJC00540(to CZ).
There is increasing evidence that the gut microbiota affects the incidence and progression of central nervous system diseases via the brain-gut axis.The spinal cord is a vital important part of the central nervous sys...
关键词：CHEMOKINES CYTOKINES gut microbiota NLRP3 spinal cord injury Toll-like receptor ligand TRYPTOPHAN 
Immunoglobulin G-mediated food intolerance and metabolic syndrome influence the occurrence of reflux esophagitis in Helicobacter pylori-infected patients被引量：2
《World Journal of Gastroenterology》2024年第8期855-862,共8页Li-Hui Wang Bin-Bin Su Sheng-Shu Wang Guan-Chao Sun Kun-Ming Lv Yi Li Hui Shi Qian-Qian Chen 
This study was reviewed and approved by the Ethics Committee of the PLA General Hospital(Ethics audits No.S2022-414-01).
BACKGROUND Reflux esophagitis has an increasing prevalence and complex and diverse symptoms.Identifying its risk factors is crucial to understanding the etiology,prevention,and management of the disease.The occurrence...
关键词：Gastroesophageal reflux ESOPHAGITIS Food intolerance Metabolic syndrome Helicobacter pylori CHEMOKINES 
Roles of Major Chemokines in the Pathophysiology of Atrial Fibrillation
《Cardiovascular Innovations and Applications》2024年第1期705-710,共6页Saira Rafaqat Fozia Bibi Muhammad Aqib Murad Huma Khurshid Amna Sheerin 
Chemokines are a subclass of cytokines,a large family of small secreted proteins that communicate via G protein-coupled heptahelical chemokine receptors on the cell surface.Atrial fibrillation(AF)is the most prevalent...
关键词：atrial fibrillation CHEMOKINES pathophysiology aspects inflammation 
Evolutionary traits and functional roles of chemokines and their receptors in the male pregnancy of the Syngnathidae被引量：1
《Marine Life Science & Technology》2023年第4期500-510,共11页Han Jiang Zhanwei Zhao Haiyan Yu Qiang Lin Yali Liu 
supported by the National Natural Science Foundation of China(41825013);the Marine Economic Development Project(GDNRC[2022]36);National Key R&D Program of China(2022YFC3102403);National Natural Science Foundation of China(42230409,42276127);Guangdong Basic and Applied Basic Research Foundation(2021A1515011380,2021A1515011393).
Vertebrates have developed various modes of reproduction,some of which are found in Teleosts.Over 300 species of the Syngnathidae(seahorses,pipefishes and seadragons)exhibit male pregnancies;the males have specialized...
关键词：Reproductive mode Immune response SEAHORSE Brood pouch 
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