Bill&Melinda Gates Foundation(Grant number OPP1154401).
Backgroud Before fertilization,spermatozoa undergo a crucial maturation step called capacitation,which is a unique event regulates the sperm’s ability for successful fertilization.The capacitation process takes place...
Objective:To identify the role of protein kinase in male reproduction in animal models and human spermatogenic function.Methods:This study assessed the protein kinase of male reproduction in animal models and human us...
Objective:To optimize the concentration of PDC-109 protein in semen for higher cryopreservability and fertility by sequestration or neutralization of PDC-109 by its antibodies(anti-PDC-109 antibodies)in bubaline speci...
Research was funded by grants from National University of Río Cuarto(UNRC)through the Secretary of Science and Technology(SECYT,PPI 2020-2022,Res 083).
Background:Capacitation is a set of physiological changes sperms undergo to acquire fertilizing capacity.In vivo,this process is directly associated with high calcium levels in sperm cytoplasm.Calcitriol,the vitamin D...
the Human Fertility Chair,the Department of Biotechnology of the University of Alicante(VIGROB-186);the project of the Spanish Ministry of Economy and Competitiveness(AGL2015-70159-P).
A cascade of dramatic physiological events is linked to the sperm acrosome reaction and binding to the oocyte's zona pellucida during human sperm capacitation.However,structural and functional sperm changes during cap...
This work was supported by the Military Medical Innovation Project(18CXZ038);Military Logistics Scientific Research Project(ALB19J003);Military Scientific Research Project,and Military Science Project of the National Social Science Foundation(15GJ003-155).
The outbreak of the coronavirus disease 2019(COVID-19)in December 2019 highlighted several concerns regarding hospital biosafety capacitation in the People’s Republic of China,although the epidemic is now under contr...
The purpose of this study was to evaluate the effect of the addition of Origanum vulgare extract to in vitro capacitation sperm medium (IVCSM). This study investigated the antioxidant and antimicrobial effects of O. v...
funded by "Niche area of excellence,Indian Council of Agricultural Research(ICAR),India"
Background: An oviduct-specific glycoprotein, OVGP1, is synthesized and secreted by non-ciliated epithelial cells of the mammalian oviduct which provides an essential milieu for reproductive functions. The present st...
Supported by Earmarked Fund for China Agriculture(Beef and Yak)Research System(NYCYTX-38);Key Agriculture Research and Development Program of Qiqihar(NYGG-201524)~~
In order to improve the in vitro fertilization rate of bovine, the effects of different sperm capacitation methods on fertilization were investigated. Total two treatments were designed: two-time centrifugation (C)...
This work was supported by the grants from the National Key Basic Research Program (Nos. 2014CB943103 and 2009CB941701) and the National Natural Science Foundation of China (Nos. 31471104 and 31171115).
Bisphenol A (BPA) is a synthetic estrogen-mimic chemical. It has been shown to affect many reproductive endpoints. However, the effect of BPA on the mature sperm and the mechanism of its action are not clear yet. He...