supported by the German Research Foundation (SFB-TR 295)(to MM)。
Pathological tremor is one of the cardinal symptoms in Parkinson's disease (PD).Tremor is comprised of involuntary,rhythmic,a nd oscillating movements that can vary according to the circumstances under which they occu...
partially supported by the Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research(KAKENHI,Grant numbers 23H02865[to KK],23K14927[to CA]);the Brain/MINDS Beyond program of the Japan Agency for Medical Research and Development(Grant Number JP19dm0307101[to KK])。
Parkinson's disease(PD)is a progressive neurodegenerative disorder characterized primarily by classical motor signs of bradykinesia,rigidity,tremors,and postural instability usually manifesti ng unilate rally or at le...
supported by the Deutsche Forschungsgemeinschaft(DFG,German Research Foundation)Project-ID 424778381-TRR 295(to MM);the Fondazione Grigioni per il Morbo di Parkinson(to IUI).
Tremor occurs in about half of multiple sclerosis(MS)patients.MS tremor has a broad frequency range of 2.5-7 Hz,with a higher prevalence of postural tremor(44%)compared to intentional tremor(6%)(Alusi et al.,2001).Tre...
supported by the Natural Science Foundation of China;Nos.81971212 (to FG);81601129 (to XXX);the Open Fund of the Key Laboratory of Medical Electrophysiology;Ministry of Education&Medical Electrophysiological Key Laboratory of Sichuan Province;Institute of Cardiovascular Research;Southwest Medical University;No.KeyME-2018-07 (to FG);Liaoning Province Xingliao Talent Program Project;No.XLYC1907164 (to FG)
Dysfunction of neuronal nitric oxide synthase contributes to neurotoxicity,which triggers cell death in various neuropathological diseases,including epilepsy.Studies have shown that inhibition of neuronal nitric oxide...
supported by the National Key Research and Development Program Sub-project, No.2018 YFC0115405(to BYF);the Start-up Fund for Scientific Research Talents of Beijing Rehabilitation Hospital, Capital Medical University of China, No.2019 R-006(to ZHJ)。
Parkinson's disease(PD) can be classified into three motor-based subtypes: postural instability/gait difficulty(PIGD), tremor dominant(TD), and indeterminate.The neuropathophysiological mechanisms of the three motor s...
supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(NRF-2018R1A6A3A11043447,to HDL)。
Post-traumatic movement disorder is one of the sequelae of traumatic brain injury. The dentatorubrothalamic tract(DRTT) is reported to be involved in the control of movement. Therefore, injury of the DRTT can be accom...
supported by the Science and Technology Foundation of Guangdong Province of China,No.2014A030304019;the Natural Science Foundation of Guangdong Province of China,No.2015A030313164
Deep brain stimulation of the subthalamic nucleus is recognized as the most effective treatment for moderate and advanced Parkinson's disease. Programming of the stimulation parameters is important for maintaining th...
Parkinson’s disease(PD)is a progressive neurodegenerative disorder clinically characterized by motor symptoms(bradykinesia,tremor,rigidity,postural instability)and non-motor symptoms(hyposmia,sleep disorders,aut...