相关期刊:《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Science China Chemistry》《Chemical Research in Chinese Universities》《Asian Journal of Andrology》更多>>
supported by the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(CIFMS,No.2016-I2M-3–012);the Fundamental Research Funds for the Central Universities of Chinese Academy of Medical Sciences&Peking Union Medical College(2016ZX350001);Beijing Natural Science Foundation(No.7172143)
The search of new substrates with pharmaceutical and industrial potential for biocatalysts including cytochrome P450 enzymes is always challenging. Cytochrome P450 BM3 mutant 139-3, a versatile biocatalyst, exhibited ...
Clinical trials of weak androgen androstenedione (AD) administered at a high concentration, showed an increase in muscle mass in men like strong androgens testosterone (T) and dihydrotestosterone (DHT), but did not sh...
Project (No. 31130042) support by the National Natural ScienceFoundation of China
Biotransformation of phytosterol(PS) by a newly isolated mutant Mycobacterium neoaurum ZJUVN-08 to produce androstenedione has been investigated in this paper.The parameters of the biotransformation process were optim...
Supported by the National Natural Science Foundation of China(No.20576094)
A series of novel 7-amide substituted-4-androstene-3,17-dione derivatives(8αa "8αh or 8βa "8βh) was synthesized from the important intermediates 5 by N-acylation and acidic hydrolysis.Compounds 5α and 5β wer...
Aim: To study the effects of Boesenbergia rotunda (Krachai) on sexual behaviour in male albino rats. Methods: Thirty-two male Wistar rats were equally divided into four groups: experimental groups were gavaged wi...
Project supported by one of the National Research Subjects in the Seventh Five-Year Science and Technology Plan and the National Natural Science Foundation of China
Five hybridomas stably secreting monoclonal antibodies (McAbs) to androstenedione were prepared by using artificially synthesized androstenedione-11α-succinyl conjugate with bovine serum albumin (BSA) as antigen. The...