supported by the German Research Council(Deutsche Forschungsgemeinschaft,HA3309/3-1/2,HA3309/6-1,HA3309/7-1)。
Skeletal muscles are essential for locomotion,posture,and metabolic regulation.To understand physiological processes,exercise adaptation,and muscle-related disorders,it is critical to understand the molecular pathways...
This work was supported by the National Natural Science Foundation of China(T2222029 and U21A20396);the Strategic Priority Research Program of Chinese Academy of Sciences(XDA16020802);CAS Engineering Laboratory for Intelligent Organ Manufacturing(KFJ-PTXM-039);CAS Project for Young Scientists in Basic Research(YSBR‐012);the fellowship of China Postdoctoral Science Foundation(2021M693163).
Electrospun scaffolds with aligned fiber orientation are widely used in tissue engineering,such as muscle,heart,nerve,tendon,and cartilage,due to their ability to guide cell morphology and induce cellular functions.Ho...
Xizang Major Science and Technology Project(XZ202101ZD0005N);Yunnan Major Science and Technology Project(202302AE090015);National Key R&D Program of China(2023ZD04044-04);National Natural Science Foundation of China(32060736)。
Tumor necrosis factorα(TNFα)exhibits diverse biological functions;however,its regulatory roles in myogenesis are not fully understood.In the present study,we explored the function of TNFαin myoblast proliferation,d...
supported by the National Key Research and Development Program of China(2022YFF10002020);Sichuan Science and Technology Program,China(2021YFYZ0007 and 2021YFYZ0031).
MicroRNAs(miRNAs)have been demonstrated to control chicken skeletal muscle growth,however,the potential function of the miR-181-5p family in chicken myogenesis remains largely unknown.Here,our study identified the two...
supported by the National Natural Science Foundation of China(31830090);the High-level Talent Project of Shihezi University,China(2022ZK022);the Agricultural Science and Technology Innovation Program,Chinese Academy of Agricultural Sciences(CAAS-ZDRW202006).
Global demand for farm animals and their meat products i.e.,pork,chicken and other livestock meat,is steadily incresing.With the ongoing life science research and the rapid development of biotechnology,it is a great o...
funded by the National Natural Science Foundation of China(31972559,31902183);the Distinguished and Excellent Young Scholar Cultivation Project of Shanxi Agricultural University(2022JQPYGC01)。
Vitamin A and its metabolite,retinoic acid(RA)play important roles in regulating skeletal muscle development.This study was conducted to investigate the effects of early intramuscular vitamin A injection on the muscle...
supported by the National Natural Science Foundation of China[Grant No.31972558];the Agricultural Improved Seed Project of Shandong Province[Grant No.2020LZGC014-03]。
Background Sharply increased beef consumption is propelling the genetic improvement projects of beef cattle in China.Three-dimensional genome structure is confirmed to be an important layer of transcription regulation...
supported by The National Natural Science Foundation of China(No.31830090);The Basic and Applied Basic Research Foundation of Guangdong province,China(No.2019B1515120059);The Agricultural Science and Technology Innovation Program,China(No.CAAS-ZDRW202006).
Skeletal muscle is the largest motor and metabolic organ of the body, which has a robust capacity for regeneration following injury or disease. Delayed regeneration after skeletal muscle injury reduces muscle contract...
supported by the Agricultural Science and Technology Innovation Program and The Elite Young Scientists Program of CAAS.ZT was supported by the National Natural Science Foundation of China(31830090);the Basic and Applied Basic Research Foundation of Guangdong province(2019B1515120059);the Shenzhen Dapeng New District Special Fund for Industry Development(KY20180114);the Agricultural Science and Technology Innovation Program(CAAS-ZDRW202006).
Background:N6-methyladenosine(m^(6)A)and DNA 5-methylcytosine(5mC)methylation plays crucial roles in diverse biological processes,including skeletal muscle development and growth.Recent studies unveiled a potential li...
This work was supported by the Strategic Priority Research Program of the Chinese Academy of Science(XDA16020400 to P.H.);Ministry of Science and Technology of China(2017YFA0102700 to P.H.);the National Natural Science Foundation of China(32170804 to P.H.and 81200355 to W.Y.);CAS-Youth Innovation Program Association(2016246 to W.Y.);Shanghai Natural Science Foundation(18ZR1446300 to W.Y.).
Long non-coding(lnc)RNA plays important roles in many cellular processes.The function of the vast majority of lncRNAs remains unknown.Here we identified that lncRNA-1700113A16RIK existed in skeletal muscle stem cells(...