supported by the German Research Council(Deutsche Forschungsgemeinschaft,HA3309/3-1/2,HA3309/6-1,HA3309/7-1)。
Skeletal muscles are essential for locomotion,posture,and metabolic regulation.To understand physiological processes,exercise adaptation,and muscle-related disorders,it is critical to understand the molecular pathways...
supported by the National Natural Science Foundation of China(82071588,82122024);the National Key Research and Development Program of China(2022YFA1103700,2020YFA0804000,2020YFA0112200,2021YFF1201000,the STI2030-Major Projects-2021ZD0202400);the National Natural Science Foundation of China(82001477,81921006,82125011,92149301,92168201,91949209,92049304,92049116,32121001,82192863,82122024,32000500,82271600);CAS Project for Young Scientists in Basic Research(YSBR-076,YSBR-012);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16000000);the Program of the Beijing Natural Science Foundation(Z190019);the Informatization Plan of Chinese Academy of Sciences(CASWX2021SF-0301,CAS-WX2022SDC-XK14,CAS-WX2021SF-0101);New Cornerstone Science Foundation through the XPLORER PRIZE(2021-1045);Youth Innovation Promotion Association of CAS(E1CAZW0401,2022083);Excellent Young Talents Program of Capital Medical University(12300927);The Project for Technology Development of Beijing-affiliated Medical Research Institutes(11000023T000002036310);Excellent Young Talents Training Program for the Construction of Beijing Municipal University Teacher Team(BPHR202203105);Young Elite Scientists Sponsorship Program by CAST(YESS20210002);Beijing Hospitals Authority Youth Program(QML20230806).
Sarcopenia,an age-related skeletal muscle condition characterized by a progressive decline in muscle mass and function,is linked to increased vulnerability,a higher likelihood of falls,and higher mortality rates in ol...
the National Natural Science Foundation of China(32172695);Natural Science Foundation of Anhui Province,China(2108085Y11);China Agriculture Research System(CARS-38);the Open Project of Anhui Key Laboratory of Embryonic Development and Reproductive Regulation,Anhui Provincial Department of Science and Technology,China(FSKFKT019D)。
Muscle fibers are the main component of skeletal muscle and undergo maturation through the formation of myotubes.During early development,a population of skeletal muscle satellite cells(SSCs)proliferate into myoblasts...
funded by the National Basic Research Program of China(973 Program),No.2014CB542201;the National High Technology Research and Development Program of China(863 Program),No.SS2015AA020501;the National Natural Science Foundation of China(General Program),No.31571235,31771322,31671248,31571236,31271284,31171150,81171146,31471144,30971526,31100860,31040043,31371210,and 81372044
Delay of axon regeneration after peripheral nerve injury usually leads to progressive muscle atrophy and poor functional recovery. The Wnt/β-catenin signaling pathway is considered to be one of the main molecular mec...
Lipopolysaccharide (LPS) is considered as a powerful inducer of muscle atrophy in higher verte- brates due to skeletal muscle cell recognition of the endotoxin and a consequent activation of cata- bolic signaling pa...
Skeletal muscle development is influenced by myogenic regulatory factors, including the expression of MyoD and myogenin. Our objective was to use the C2C12 cell culture model to test the hypothesis that both MyoD and ...
A 22-mer peptide, identical to the primary sequence of domain I segment 4 (IS4) of rat brain sodium channel I, has been synthesized. IS4 peptide can incorporate into cultured rat skeletal myotube membranes and form io...