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PATHOGEN: 作品数：426被引量：1205H指数：16; 导出分析报告; 相关领域：农业科学医药卫生更多>>; 相关作者：张国辉王火旭李洪艳方宏筠王关林更多>>; 相关机构：凯里学院沈阳农业大学云南农业大学安徽师范大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>

Immunopathogenesis and immunomodulatory therapy for myocarditis被引量：7: 《Science China(Life Sciences)》2023年第9期2112-2137,共26页Wu He Ling Zhou Ke Xu Huihui Li James Jiqi Wang Chen Chen DaoWen Wang; supported by the National Natural Science Foundation of China (81790624 and C-0052);Natural Science Foundation of Hubei Province (2020CFA016)。; Myocarditis is an inflammatory cardiac disease characterized by the destruction of myocardial cells, infiltration of interstitial inflammatory cells, and fibrosis, and is becoming a major public health concern. The ae...; 关键词：MYOCARDITIS ETIOLOGY PATHOGEN IMMUNOPATHOGENESIS IMMUNOMODULATORY

Pathogen-associated T follicular helper cell plasticity is critical in anti-viral immunity被引量：1: 《Science China(Life Sciences)》2022年第6期1075-1090,共16页Han Feng Xiaohong Zhao Jenny Xie Xue Bai Weiwei Fu Hairong Chen Hong Tang Xiaohu Wang Chen Dong; supported in part by the National Natural Science Foundation of China(31630022,31821003,31991170 and 31600718);Beijing Municipal Science and Technology Commission(Z181100001318007 and Z171100000417005)。; T follicular helper(Tfh)cells are critical in providing help for B cells in the germinal center reaction.Tfh cell plasticity,especially with regard to their expression of effector Th cytokines,has been described,but l...; 关键词：T follicular helper(Tfh)cell PLASTICITY influenza infection IFN-γ IgG2

Genome sequencing of the bacterial blight pathogen DY89031 reveals its diverse virulence and origins of Xanthomonas oryzae pv.oryzae strains被引量：2: 《Science China(Life Sciences)》2021年第12期2175-2185,共11页Fudan Chen Bingxiao Yan Xiangyu Gong Helin Li Zuhua He; supported by Chinese Academy of Sciences(XDB27040201);the National Natural Science Foundation of China(3181101746)。; The bacterial pathogen Xanthomonas oryzae pv.oryzae(Xoo),belonging to Xanthomonas sp.,causes one of the most destructive vascular diseases in rice worldwide,particularly in Asia and Africa.To better understand Xoo pat...; 关键词：DY89031 genome sequencing TAL effectors non-TAL effectors Xanthomonas oryzae pv.Oryzae

Molecular actions of NLR immune receptors in plants and animals被引量：12: 《Science China(Life Sciences)》2020年第9期1303-1316,共14页Jizong Wang Jijie Chai; supported by the Alexander von Humboldt Foundation(Humboldt Professorship of Jijie Chai)。; NLRs constitute intracellular immune receptors in both plants and animals. Direct or indirect ligand recognition results in formation of oligomeric NLR complexes to mediate immune signaling. Over the past 20 years, ra...; 关键词：NLR immune receptor autoihibition pathogen perception resistosome/inflammasome molecular mechanism

Insights into receptor-like kinases-activated downstream events in plants被引量：1: 《Science China(Life Sciences)》2018年第12期1586-1588,共3页Xuming Luo Jun Liu; Unlike vertebrates that have the circulating immune system, plants have evolved an efficient innate immune system to defend against invading pathogens.At cellular level,the plant innate immunity primarily relies on pl...; 关键词：Unlike vertebrates Upon PATHOGEN

Pathogen genomic surveillance elucidates the origins, transmission and evolution of emerging viral agents in China被引量：4: 《Science China(Life Sciences)》2017年第12期1317-1330,共14页Weifeng Shi Juan Li Hong Zhou George F.Gao; supported by the China Ministry of Science and Technology(MOST)Key Research and Development Program(2017ZX10104001);the Taishan Scholars program of Shandong province(ts201511056 to Weifeng Shi); In the past twenty years, numerous novel zoonotic viral agents with pandemic potential have emerged in China, such as the severe acute respiratory syndrome(SARS) coronavirus and, more recently, the avian-origin influe...; 关键词：emerging infectious diseases SARS-CoV MERS-CoV genomic surveillance H7N9 Zika EBOLA

Antibiotic growth promoter olaquindox increases pathogen susceptibility in fish by inducing gut microbiota dysbiosis被引量：12: 《Science China(Life Sciences)》2017年第11期1260-1270,共11页suxu he quanmin wang shuning li chao ran xiaoze guo zhen zhang zhigang zhou; supported by the National Basic Research Program of China (2015CB150605);the National Natural Science Foundation of China (31272672, 31572633);the Beijing Earmarked Fund for Modern Agro-industry Technology Research System (SCGWZJ 20161104-4);the Fundamental Research Funds for the Central Public Welfare Research Institute (1610382016013); Low dose antibiotics have been used as growth promoters in livestock and fish. The use of antibiotics has been associated with reduced pathogen infections in livestock. In contrast, antibiotic growth promoter has been...; 关键词：antibiotic growth promoter pathogen susceptability gut microbiota FISH OLAQUINDOX

Expansion of pathogen recognition specificity in plants using pattern recognition receptors and artificially designed decoys被引量：6: 《Science China(Life Sciences)》2017年第8期797-805,共9页Lifan Sun Jun Qin Kailun Wang Jie Zhang; supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB11020600);National Natural Science Foundation of China(31571968,31300234);the Youth Innovation Promotion Association of the Chinese Academy of Sciences; Pathogen/microbe-associated molecular patterns(PAMPs/MAMPs) are recognized by plant pattern recognition receptors(PRRs)localized on the cell surface to activate immune responses.This PAMP-triggered immunity(PTI) confe...; 关键词：pattern recognition receptor EFFECTOR DECOY PAMP-triggered immunity resistance

Transient silencing mediated by in vitro synthesized double-stranded RNA indicates that PsCdc14 is required for sporangial development in a soybean root rot pathogen被引量：3: 《Science China(Life Sciences)》2011年第12期1143-1150,共8页ZHAO Wei YANG XinYu DONG SuoMeng SHENG YuTing WANG YuanChao ZHENG XiaoBo; supported by the Special Fund for Agro-Scientific Research in the Public Interest (Grant No. 3-20) from the Chinese government;the Priority Academic Program Development for Jiangsu Higher Education Institutions; In many eukaryotic organisms, Cdcl4 phosphatase regulates multiple biological events during anaphase and is essential for mitosis. It has been shown that Cdcl4 is required for sporulation in the potato blight pathogen...; 关键词：Phytophthora sojae PsCdc14 SPORANGIUM transient gene silencing

Identification of an avirulence gene,avrxa5,from the rice pathogen Xanthomonas oryzae pv.oryzae被引量：9: 《Science China(Life Sciences)》2010年第12期1440-1449,共10页ZOU HuaSong ZHAO WenXiang ZHANG XiFu HAN YangChun ZOU LiFang CHEN GongYou; supported by the State Key Basic Research and Development Project of China (Grant No. 2006CB101902);the National Natural Science Foundation of China (Grant Nos. 30710103902 and 30671354);the Ministry of Agriculture of China (Grant No. NYHYZX07-056); Xanthomonas oryzae pv.oryzae,the causal agent of bacterial blight in rice,interacts with rice plants in a gene-for-gene manner.The specificity of the interaction is dictated by avirulence(avr) genes in the pathogen an...; 关键词：rice bacterial blight Xanthomonas oryzae pv.oryzae avrxa5 AVIRULENCE recessive resistance

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