ISOCHROMAN

作品数:8被引量:7H指数:2
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相关领域:化学工程医药卫生更多>>
相关机构:中国科学院大学更多>>
相关期刊:《Chinese Journal of Chemistry》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Chinese Journal of Structural Chemistry》更多>>
相关基金:国家自然科学基金广东省自然科学基金更多>>
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Cobalt-Catalyzed Switchable[4+1]and[4+1+1]Spirocyclization of Aromatic Amides with 2-Diazo-1H-indene-1,3(2H)-dione:Access to Spiro Indene-2,1'-isoindolinones and Spiro Isochroman-3,1'-isoindolinones
《Chinese Journal of Chemistry》2024年第4期363-369,共7页Bin Li Mengmeng Xie Jingyu Li Nana Shen Xinying Zhang Xuesen Fan 
the National Natural Science Foundation of China(22101075,U2004189);Central Plains Science and Technology Innovation Leader Project(224200510009);Postdoctoral Research Grant in Henan Province(202103085);Henan Key Laboratory of Organic Functional Molecules and Drug Innovation,and 111 Project(D17007)for financial support.
Herein,we report a condition-controlled divergent synthesis of spiro indene-2,1'-isoindolinones and spiro isochroman-3,1'-isoindolinones through cobalt-catalyzed formal[4+1]and[4+1+1]spirocyclization of aromatic amide...
关键词:Spiro indene-2 1'-isoindolinones Spiro isochroman-3 1'-isoindolinones 3d Transition metals Cobalt-catalyzed C-H Activation Switchable[4+1]and[4+1+1]spirocyclization Aromatic amides 2-Diazo-1H-indene-1 3(2H)-dione 
Green Oxidation of Isochromans to Isochromanones with Molecular Oxygen Catalyzed by a Tetranuclear Vanadium Cluster
《Chinese Journal of Chemistry》2023年第16期1967-1972,共6页Huixin Huang Baokuan Chen Yiru Fu Jing Sun Yanfeng Bi Ming-Dong Zhou 
the National Natural Science Foundation of China(22171122);the Liaoning Revitalization Talents Program(XLYC2007130);Talent Scientific Research Fund of Liaoning Petrochemical University(2016XJL-019).
Comprehensive Summary Isochromanone is the core structure of many bioactive compounds.Direct oxidation of isochromans is one of leading methods for the construction of isochromanones,while most established processes r...
关键词:Isochromanone Vanadium cluster Green catalysis Isochroman oxidation Heterogeneous Crystal engineering ORGANOCATALYSIS C-H activation 
An optically active isochroman-2H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways
《Acta Pharmacologica Sinica》2021年第1期36-44,共9页Ling-xue Tao Sha-sha Ji Dóra Szalóki Tibor Kovács Attila Mándi Sándor Antus Xun Ding Tibor Kurtán Hai-yan Zhang 
This work was supported by the National Natural Science Foundation of China(grant numbers.81703507,81872859,81522045);The research of the Hungarian authors was supported by the EU and cofinanced by the European Regional Development Fund under the project GINOP-2.3.2-15-2016-00008 and the National Research Development and Innovation Office(grant number:K-120181).
Increasing evidence suggests that the use of potent neuroprotective agents featured with novel pharmacological mechanism would offer a promising strategy to delay or prevent the progression of neurodegeneration.Here,w...
关键词:NEURODEGENERATION oxidative stress apoptosis MAPK pathway PI3K/Akt pathway SH-SY5Y neuroblastoma cells 
New furo[3,2-h]isochroman from the mangrove endophytic fungus Aspergillus sp. 085242被引量:3
《Chinese Journal of Natural Medicines》2020年第11期855-859,共5页GUO Hui-Xian HUANG Cui-Ying YAN Zhang-Yuan CHEN Tao HONG Kui LONG Yu-Hua 
supported by the National Natural Science Foundation of China (No. 41876153);Guangdong Special Fund for Marine Economic Development (No. GDME-2018C004);the Natural Science Foundation of Guangdong Province (No.2017A030313088)。
Four new compounds, asperisocoumarin G(1), asperisocoumarin H(2),(±)-asperisocoumarin I [(±)-3], along with the known pergillin(4) and penicisochroman L(5) were isolated from a mangrove endophytic fungus Aspergillus...
关键词:ASPERGILLUS Furo[3 2-h]isocoumarins α-Glucosidase inhibitory activity Antimicrobial activity 
Anti-lung Cancer Activity and Docking Study of Two Novel Isochroman Derivatives
《Chinese Journal of Structural Chemistry》2020年第5期901-907,共7页LI Di 
supported by the Project of Inner Mongolia University for the Nationalities(No.NMDYB15064);Science Research Project of Inner Mongolia Education Department(No.NJZY20114)。
Two new isochroman derivatives(1 and 2)were isolated from the fermentation products of mangrove endophytic fungus Phomopsis sp.33#.Their structures were characterized by IR,~1 H NMR,H RMS,and single-crystal X-ray crys...
关键词:isochroman derivatives anticancer activity MTT assay molecular docking 
Synthesis, Crystal Structure and Biological Evaluation of 6'-Chloro-4'-methylene-3H-spiro[isobenzofuran-1,3'-isochroman]
《Chinese Journal of Structural Chemistry》2019年第1期89-94,3,共7页PU Xiu-Ying XU Wen-Jun YI Yun-Peng LI Hao-Wen LIANG Jian-Ping HAO Bao-Cheng 
National Key Technology Support Program(No.2015BAD11B02);Agricultural Science and Technology Innovation Program(ASTIP,No.CAASASTIP-2014-LIHPS-04)
The title compound 6?-chloro-4?-methylene-3 H-spiro [isoben zofura-1,3?-isochroman], C_(17)H_(13)ClO_2, was prepared and characterized by IR, NMR, HRMS and single-crystal X-ray diffraction. This compound has a bisbenz...
关键词:3H-spiro[isobenzofura-1 3'-isochroman] single-crystal structure ANTI-BACTERIAL 
Synthesis and Acid-Catalyzed Cyclization of 2-Alkenylstilbenes: a New Approach to the Substituted Indenes
《Chinese Journal of Chemistry》2015年第11期1276-1286,共11页Wei Ding Xiaoxin Shi Xia Lu 
We are grateful to the National Natural Science Foundation of China (No. 20972048) for the financial support of this work
A base-catalyzed ring-opening of 1-benzylisochromans 1 firstly produced 2-alkenylstilbenes 2, which then underwent a mild acid-catalyzed intramolecular cyclization to furnish 1,2-disubstituted indenes 3 in high yields...
关键词:ISOCHROMAN STILBENE INDENE CYCLIZATION ring-opening synthetic methodology 
A new isochroman-4-one derivative from the peel of Musa sapientum L.and its total synthesis被引量:4
《Chinese Chemical Letters》2007年第10期1227-1230,共4页Hai Qian Wen Long Huang Xiao Ming Wu Hui Bin Zhang Jin Pei Zhou Wen Cai Ye 
A new isochroman-4-one, 7,8-dihydroxy-3-methylisochroman-4-one was isolated from water soluble fraction of Musa sapientum L. Its structure was determined by spectroscopic evidences and its total synthesis has also bee...
关键词:Isochroman-4-one Musa sapientum L. ISOLATION Total synthesis 
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