the National Natural Science Foundation of China(22101075,U2004189);Central Plains Science and Technology Innovation Leader Project(224200510009);Postdoctoral Research Grant in Henan Province(202103085);Henan Key Laboratory of Organic Functional Molecules and Drug Innovation,and 111 Project(D17007)for financial support.
Herein,we report a condition-controlled divergent synthesis of spiro indene-2,1'-isoindolinones and spiro isochroman-3,1'-isoindolinones through cobalt-catalyzed formal[4+1]and[4+1+1]spirocyclization of aromatic amide...
the National Natural Science Foundation of China(22171122);the Liaoning Revitalization Talents Program(XLYC2007130);Talent Scientific Research Fund of Liaoning Petrochemical University(2016XJL-019).
Comprehensive Summary Isochromanone is the core structure of many bioactive compounds.Direct oxidation of isochromans is one of leading methods for the construction of isochromanones,while most established processes r...
This work was supported by the National Natural Science Foundation of China(grant numbers.81703507,81872859,81522045);The research of the Hungarian authors was supported by the EU and cofinanced by the European Regional Development Fund under the project GINOP-2.3.2-15-2016-00008 and the National Research Development and Innovation Office(grant number:K-120181).
Increasing evidence suggests that the use of potent neuroprotective agents featured with novel pharmacological mechanism would offer a promising strategy to delay or prevent the progression of neurodegeneration.Here,w...
supported by the National Natural Science Foundation of China (No. 41876153);Guangdong Special Fund for Marine Economic Development (No. GDME-2018C004);the Natural Science Foundation of Guangdong Province (No.2017A030313088)。
Four new compounds, asperisocoumarin G(1), asperisocoumarin H(2),(±)-asperisocoumarin I [(±)-3], along with the known pergillin(4) and penicisochroman L(5) were isolated from a mangrove endophytic fungus Aspergillus...
supported by the Project of Inner Mongolia University for the Nationalities(No.NMDYB15064);Science Research Project of Inner Mongolia Education Department(No.NJZY20114)。
Two new isochroman derivatives(1 and 2)were isolated from the fermentation products of mangrove endophytic fungus Phomopsis sp.33#.Their structures were characterized by IR,~1 H NMR,H RMS,and single-crystal X-ray crys...
National Key Technology Support Program(No.2015BAD11B02);Agricultural Science and Technology Innovation Program(ASTIP,No.CAASASTIP-2014-LIHPS-04)
The title compound 6?-chloro-4?-methylene-3 H-spiro [isoben zofura-1,3?-isochroman], C_(17)H_(13)ClO_2, was prepared and characterized by IR, NMR, HRMS and single-crystal X-ray diffraction. This compound has a bisbenz...
We are grateful to the National Natural Science Foundation of China (No. 20972048) for the financial support of this work
A base-catalyzed ring-opening of 1-benzylisochromans 1 firstly produced 2-alkenylstilbenes 2, which then underwent a mild acid-catalyzed intramolecular cyclization to furnish 1,2-disubstituted indenes 3 in high yields...
A new isochroman-4-one, 7,8-dihydroxy-3-methylisochroman-4-one was isolated from water soluble fraction of Musa sapientum L. Its structure was determined by spectroscopic evidences and its total synthesis has also bee...