EPILEPTOGENESIS

作品数：29被引量：56H指数：5
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相关领域：医药卫生更多>>
相关期刊：《Chinese Medical Journal》《Neuroimmunology and Neuroinflammation》《Acta Epileptologica》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》更多>>
相关基金：国家自然科学基金上海市浦江人才计划项目中国博士后科学基金国家教育部博士点基金更多>>
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  • 期刊=Neural Regeneration Researchx
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Metabotropic glutamate receptors(mGluRs)in epileptogenesis:an update on abnormal mGluRs signaling and its therapeutic implications被引量：3
《Neural Regeneration Research》2024年第2期360-368,共9页Leyi Huang Wenjie Xiao Yan Wang Juan Li Jiaoe Gong Ewen Tu Lili Long Bo Xiao Xiaoxin Yan Lily Wan 
supported by the Natural Science Foundation of Hunan Province,No.2021JJ30389(to JG);the Key Research and Development Program of Hunan Province of China,Nos.2022SK2042(to LL)and 2020SK2122(to ET)。
Epilepsy is a neurological disorder characterized by high morbidity,high recurrence,and drug resistance.Enhanced signaling through the excitatory neurotransmitter glutamate is intricately associated with epilepsy.Meta...
关键词：antiepileptic drugs EPILEPTOGENESIS metabotropic glutamate receptors(mGluRs) signal pathways therapeutic potentials 
Pro-and anti-epileptic roles of microglia被引量：10
《Neural Regeneration Research》2021年第7期1369-1371,共3页Shinichi Kinoshita Ryuta Koyama 
supported in part by a Grant-in-Aid for Scientific Research (B)(17H03988 to RK) from JSPS and JST PRESTO (JPMJPR18H4 to RK)。
Microglia are brain-resident immune cells that contribute to the maintenance of brain homeostasis.In the epileptic brain, microglia show various activation phenotypes depending on the stage of epileptogenesis.Therefor...
关键词：EPILEPSY EPILEPTOGENESIS inflammatory cytokines MICROGLIA NEUROGENESIS neuron-microglia interaction SEIZURE 
Glycolysis in energy metabolism during seizures
《Neural Regeneration Research》2013年第14期1316-1326,共11页Heng Yang Jiongxing Wu Ren Guo Yufen Peng Wen Zheng Ding Liu Zhi Song 
supported by the National Natural Science Foundation of China,No.30971534;125 Project of the Third Xiangya Hospital,China
Studies have shown that glycolysis increases during seizures, and that the glycolytic metabolite lactic acid can be used as an energy source. However, how lactic acid provides energy for seizures and how it can partic...
关键词：neural regeneration reviews epilepsy energy metabolism GLYCOLYSIS EPILEPTOGENESIS terminationATP aerobic metabolism 6-diphosphate kinase-1 N-methyI-D-aspartate receptor acid-sensitive1A ion channel y-aminobutyric acid intra- and extracellular environment voltage-gated Na＋ andCa2＋ adenosine receptors ATP receptor grants-supported paper NEUROREGENERATION 
Changes in synaptic and extrasynaptic N-methyl-D-aspartate receptor-mediated currents at early-stage epileptogenesis in adult mice
《Neural Regeneration Research》2011年第2期118-124,共7页Juegang Ju Sheng-tian Li 
Shanghai Pujiang Program,No. 06PJ14053;the National Natural Science Foundation of China,No. 30600177;the Scientific Research Founda-tion for the Returned Over-seas Chinese Scholars,State Education Ministry;Doctoral Fund of Ministry of Education of China,No. 20070248083;Shanghai Leading Aca-demic Discipline Project,No. B205
Previous reports have shown that N-methyl-D-aspartate （NMDA） receptors are extensively involved in epilepsy genesis and recurrence. Recent studies have shown that synaptic and extrasynaptic NMDA receptors play diffe...
关键词：N-methyl-D-aspartate receptor excitatory postsynaptic current epilepsy EPILEPTOGENESIS hippocampus 
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