EPILEPSY

作品数:786被引量:1111H指数:13
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相关作者:熊志奇岳旺王蕾张芳陈迁更多>>
相关机构:首都医科大学复旦大学中国科学院上海生命科学研究院青岛大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Brain injury biomarkers and applications in neurological diseases被引量:1
《Chinese Medical Journal》2025年第1期5-14,共10页Han Zhang Jing Wang Yang Qu Yi Yang Zhen-Ni Guo 
supported by the National Natural Science Foundation of China(No.81971105);the Science and Technology Department of Jilin Province(No.YDZJ202201ZYTS677);the Norman Bethune Health Science Center of Jilin University(No.2022JBGS03);Science and Technology Department of Jilin Province(Nos.YDZJ202302CXJD061 and 20220303002SF);Jilin Provincial Key Laboratory(No.YDZJ202302CXJD017).
Neurological diseases are a major health concern,and brain injury is a typical pathological process in various neurological disorders.Different biomarkers in the blood or the cerebrospinal fluid are associated with sp...
关键词:Brain injury Biomarkers EPILEPSY Neurological diseases STROKE 
Safety and efficacy of a novel responsive neurostimulation system in China for drug-refractory focal epilepsy:The first-in-man study被引量:1
《Chinese Medical Journal》2024年第12期1486-1488,共3页Kailiang Wang Yongzhi Shan Penghu Wei Liankun Ren Liang Chen Junming Zhu Guoguang Zhao 
supported by grants from the National Natural Science Foundation of China(Nos.82030037,81801288,and 81871009);STI2030-Major Projects(No.2021ZD0201801);the Translational and Application Project of Brain-inspired and Network Neuroscience on Brain Disorders,Beijing Municipal Health Commission(No.11000022T000000444685)
To the Editor:Recent studies have characterized drugresistant epilepsy(DRE)as essentially a neural network disease.[1]Detection and disconnection of this pathological epileptic connectome or network can greatly improv...
关键词:EPILEPSY STIMULATION DRUG 
Burden of epilepsy in China and its provinces,1990 to 2019:findings from the Global Burden of Disease Study 2019被引量:11
《Chinese Medical Journal》2023年第3期305-312,共8页Wei Liu Yangyang Xu Yicong Lin Lijun Wang Maigeng Zhou Peng Yin Guoguang Zhao 
Background: Epilepsy accounts for a significant portion of the global disease burden. However, little is known about the disease burden of epilepsy in China and its provinces. Methods: We assessed the burden of epilep...
关键词:Aged EPILEPSY Global Burden of disease Quality-adjusted life years Disability-adjusted life years INCIDENCE Prevalence China 
Surgical treatment strategies for hemimasticatory spasms
《Chinese Medical Journal》2022年第9期1105-1107,共3页Qizhuang Li Xiaosong Wang Lin Wang Guoqiang Chen 
To the Editor:Hemimasticatory spasm(HMS)is a relatively rare type of unilateral trigeminal nerve(TN)motor branch dysfunction,whose pathogenesis is currently unknown.The clinical manifestations of HMS are involuntary p...
关键词:SPASM EPILEPSY TREATMENT 
Anterior thalamic nuclei deep brain stimulation inhibits mossy fiber sprouting via 3′,5′-cyclic adenosine monophosphate/protein kinase A signaling pathway in a chronic epileptic monkey model被引量:1
《Chinese Medical Journal》2021年第3期326-333,共8页Ting-Ting Du Ying-Chuan Chen Guan-Yu Zhu De-Feng Liu Yu-Ye Liu Tian-Shuo Yuan Xin Zhang Jian-Guo Zhang 
National Nature Science Foundation of China(Nos.81671104,81701268,61761166004,and 81830033);Beijing Municipal Administration of Hospitals’Ascent Plan(No.DFL20150503);Capital Health Research and Development of Special(No.2018-2-1076);China Postdoctoral Science Foundation(No.2018T110120)。
Background:Anterior thalamic nuclei(ATN)deep brain stimulation(DBS)is an effective method of controlling epilepsy,especially temporal lobe epilepsy.Mossy fiber sprouting(MFS)plays an indispensable role in the pathogen...
关键词:Anterior thalamic nuclei Deep brain stimulation EPILEPSY HIPPOCAMPUS Mossy fiber sprouting 
A study of medial and lateral temporal lobe epilepsy based on stereoelectroencephalography被引量:5
《Chinese Medical Journal》2021年第1期68-72,共5页Xiao-Ming Yan Cui-Ping Xu Yu-Ping Wang Kai Ma Tao Yu Xiao-Hua Zhang Xi Zhang Run-Shi Gao Guo-Jun Zhang Yong-Jie Li 
supported by grants from the Beijing Natural Science Foundation(No.L182015);the Beijing Hospitals Authority’s Ascent Plan(No.DFL20190801)。
Background:Patients with temporal lobe epilepsy(TLE)originating from different seizure onset zones had distinct electrophysiological characteristics and surgical outcomes.In this study,we aimed to investigate the rela...
关键词:EPILEPSY Stereoelectroencephalography Surgical outcome Temporal lobe 
Oxcarbazepine monotherapy in children with benign epilepsy with centrotemporal spikes improves quality of life被引量:11
《Chinese Medical Journal》2020年第14期1649-1654,共6页Wan-Ting Liu Xiu-Xian Yan Da-Zhi Cheng Han-Zi Zhang Ning Ding Ke-Ming Xu Xin-Lin Zhou Qian Chen 
This work was supported by the grants from the National Key Research and Development Program of China(Nos.2016YFC0905100 and 2016YFC1000504);the CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2016-I2M-1-002);Beijing Municipal Science&Technology Commission(No.Z171100000417020).
Background:Benign epilepsy with centrotemporal spikes(BECTS)is the most common type of childhood idiopathic focal epilepsy.BECTS is associated with pervasive cognitive deficits and behavior problems.While seizures can...
关键词:EPILEPSY Cognition Psychosocial difficulties Cognitive function Benign epilepsy with centro-temporal spikes 
Autoimmune polyendocrine syndrome type 4 with systemic lupus erythematosus and anti-phospholipid syndrome被引量:2
《Chinese Medical Journal》2020年第8期994-995,共2页Yu Wang Juan Zhao Ting-Ting Zhang Xiao-Wei Ma Jun-Qing Zhang Zhuo-Li Zhang 
A 50-year-old Chinese woman who experienced intermittent fever with xerostomia and xerophthalmia for 24 years,paroxysmal loss of consciousness for 11 years,aggravation for 1 year was admitted to the Peking University ...
关键词:admitted EPILEPSY FATIGUE 
Effect of adenovirus-mediated overexpression of PTEN on brain oxidative damage and neuroinflammation in a rat kindling model of epilepsy被引量:4
《Chinese Medical Journal》2019年第21期2628-2635,共8页Zhi-Sheng Wu Wen-Li Huang Shu-Jie Gong 
Background:Epilepsy is a chronic and severe neurological disorder.Phosphatase and tensin homolog deleted on chromosome ten(PTEN)-deficient mice exhibit learning and memory deficits and spontaneous epilepsy.The aim of ...
关键词:EPILEPSY Status epilepticus BRAIN injuries Oxidative stress Neurons Inflammation 
Broadening the phenotype of m.5703G>A mutation in mitochondrial tRNAAsn gene from mitochondrial myopathy to myoclonic epilepsy with ragged red fibers syndrome被引量:2
《Chinese Medical Journal》2019年第7期865-867,共3页Jun Fu Ming-Ming Ma Mi Pang Liang Yang Gang Li Jia Song Jie-Wen Zhang 
To the Editor:Mutations in mitochondrial DNA(mtDNA)cause mitochondrial diseases with multisystem involvement and variable clinical phenotypes.Myoclonic epilepsy with ragged red fiber(MERRF)syndrome is characterized by...
关键词:MITOCHONDRIAL tRNAAsn gene MITOCHONDRIAL MYOPATHY myoclonic EPILEPSY MITOCHONDRIAL DNA(mtDNA) 
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