SYNAPTIC

作品数:321被引量:722H指数:13
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相关领域:医药卫生生物学更多>>
相关作者:于洋余剑平赵志奇熊志奇杨柳更多>>
相关机构:中国科学院加拿大多伦多大学第四军医大学滨州医学院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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Application Analysis of Multiple Neurons Connected with Fast Inhibitory Synapses
《Journal of Bionic Engineering》2024年第4期1905-1918,共14页Wen Duan Weihai Chen Jianhua Wang Zhongcai Pei Jingmeng Liu Jianer Chen 
supported in part by the National Nature Science Foudation under Grant 62333023;in part by the Key Research and Development Program of Zhejiang Province under Grant 2021C03050;in part by the Scientific Research Project of Agriculture and Social Development of Hangzhou under Grant 20212013B11.
Almost all living organisms exhibit autonomic oscillatory activities,which are primarily generated by the rhythmic activities of their neural systems.Several nonlinear oscillator models have been proposed to elucidate...
关键词:OSCILLATOR Phase trajectory Synaptic threshold SYNCHRONIZATION Motion generation 
Aagab is required for zebrafish larval development by regulating neural activity
《Journal of Genetics and Genomics》2024年第6期630-641,共12页Shihui Ding Tursunjan Aziz Anming Meng Shunji Jia 
supported by the National Natural Science Foundation of China(#92254302,#32293202,#2019YFA0801400 to S.J.,and#31988101 to A.M.).
Clathrin-mediated endocytosis has been implicated in various physiological processes,including nutrient uptake,signal transduction,synaptic vesicle recycling,maintenance of cell polarity,and antigen presentation.Despi...
关键词:Aagab ENDOCYTOSIS Neural activity Synaptic transmitter release ZEBRAFISH 
Role of DSC1 in Drosophila melanogaster synaptic activities in response to haedoxan A
《Insect Science》2023年第6期1677-1688,共12页Xingtao Qie Yaxin Ren Xueting Chen Yuzhe Du Ke Dong Zhaonong Hu 
supported by grants from the National Natural Science Foundation of China(31672055);from the National Institutes of Health(GM080255 to K.D.).
Drosophila sodium channel 1 (DSC1) encodes a voltage-gated divalent cation channel that mediates neuronal excitability in insects. Previous research revealed that DSC1 knockout Drosophila melanogaster conferred differ...
关键词:botanical insecticide Drosophila sodium channel 1(DSCI) insect nervous system neuromuscular synapse activity REGULATORY 
Light-stimulated adaptive artificial synapse based on nanocrystalline metal-oxide film
《Opto-Electronic Science》2023年第10期1-11,共11页Igor S.Balashov Alexander A.Chezhegov Artem S.Chizhov Andrey A.Grunin Konstantin V.Anokhin Andrey A.Fedyanin 
supported by the Ministry of Science and Higher Education of the Russian Federation (Grant№075-15-2020-801);by Non-commercial Foundation for support of Science and Education 《INTELLECT》.
Artificial synapses utilizing spike signals are essential elements of new generation brain-inspired computers.In this paper,we realize light-stimulated adaptive artificial synapse based on nanocrystalline zinc oxide f...
关键词:neuromorphic photonics synaptic adaptation spiking neuron neuromorphic computing optoelectronic synaptic devises nanocrystalline metal-oxide film 
Biphasic Cholinergic Modulation of Reverberatory Activity in Neuronal
《Neuroscience Bulletin》2023年第5期731-744,共14页Xiao-Wei Li Yi Ren Dong-Qing Shi Lei Qi Fang Xu Yanyang Xiao Pak-Ming Lau Guo-Qiang Bi 
supported by grants from the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB32030200);the National Natural Science Foundation of China(31070935 and 62173326);the National Basic Research Program of China(2013CB835100);the Youth Innovation Promotion Association,CAS(2022367)。
Acetylcholine(ACh)is an important neuromod-ulator in various cognitive functions.However,it is unclear how ACh influences neural circuit dynamics by altering cellular properties.Here,we investigated how ACh influ-ence...
关键词:ACETYLCHOLINE Neuronal network REVERBERATION Synaptic current EXCITABILITY 
Direction Selectivityof TmY Neurites in Drosophila
《Neuroscience Bulletin》2023年第5期759-773,共15页Yinyin Zhao Shanshan Ke Guo Cheng Xiaohua Lv Jin Chang Wei Zhou 
supported by grants from the National Natural Science Foundation of China(61890950 and 31871027);Fundamental Research Funds for the Central Universities/HUST(2016YXMS034 and 2014TS015);the Director Fund of WNLO,and the China Postdoctoral Science Foundation(2015T80788).
The perception of motion is an important func-tion of vision.Neural wiring diagrams for extracting direc-tional information have been obtained by connectome recon-struction.Direction selectivity in Drosophila is thoug...
关键词:Direction selectivity TmY-ds-Synaptic connection Two-photon calcium imaging DROSOPHILA 
The research group of Prof. Suwei Dong has made progress in chemical synthesis of glycoprotein associated with synaptic phase separation
《Journal of Chinese Pharmaceutical Sciences》2022年第6期486-489,共4页 
5月30日,学术期刊《Nature Chemistry》在线发表北京大学化学与分子工程学院陈兴课题组与北京大学药学院天然药物及仿生药物国家重点实验室、化学生物学系董甦伟课题组合作完成、题为“O-GlcNAcylation modulates liquid-liquid phase s...
关键词:学术期刊 工程学院 北京大学药学院 神经突触 生物学系 化学合成 相分离 
Propofol reduces synaptic strength by inhibiting sodium and calcium channels at nerve terminals被引量:2
《Protein & Cell》2019年第9期688-693,共6页Qing-Zhuo Liu Mei Hao Zi-Yang Zhou Jian-Long Ge Yi-Chen Wu Ling-Ling Zhao Xiang Wu Yi Feng Hong Gao Shun Li Lei Xue 
Propofol (2,6-diisopropylphenol) has been widely used in clinical surgery because of its fast induction and rapid recovery effects (Miller et al., 2014). Although the underlying mechanisms are still controversial, man...
关键词:CONTRIBUTE to general ANESTHESIA HAS been 
ATP11B deficiency leads to impairment of hippocampal synaptic plasticity被引量:2
《Journal of Molecular Cell Biology》2019年第8期688-702,共15页Jiao Wang Weihao Li Fangfang Zhou Ruili Feng Fushuai Wang Shibo Zhang Jie Li Qian Li Yajiang Wang Jiang Xie Tieqiao Wen 
This work was supported bythe National Natural Science Foundation of China (31500827,81471162,and 61873156);Young Eastern Scholar (QD2015033);the Science and Technology Commission of Shanghai (14JC1402400);the Natural Science Foundation of Shanghai (17ZR1409900).
Synaptic plasticity is known to regulate and support signal transduction between neurons, while synaptic dysfunction contributes to multiple neurological and other brain disorders;however, the specific mechanism under...
关键词:ATP11B SYNAPTIC plasticity GLUTAMATE RECEPTORS MAPK14 signaling pathway 
A new co-culture method for identifying synaptic adhesion molecules involved in synapse formation
《Biophysics Reports》2019年第2期91-97,共7页Wei Jiang Jihong Gong Yi Rong Xiaofei Yang 
the National Natural Science Foundation of China (31670850).
The proper formation of synapses is essential for brain function. Synaptic cell adhesion molecules (CAMs) are thought to play essential roles in the initiation of the synapse formation process. The artificial synapse ...
关键词:CO-CULTURE ASSAY SYNAPSE formation SYNAPTIC cell adhesion MOLECULES POLYETHERIMIDE 
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