云南高校图书馆联盟文献共享服务平台- SULFONAMIDE

SULFONAMIDE: 作品数：73被引量：62H指数：4; 导出分析报告; 相关领域：理学医药卫生更多>>; 相关作者：池志宏牛犁王月王占友缪晓玲更多>>; 相关机构：西南大学中国医科大学清华大学宁德师范高等专科学校更多>>; 相关期刊：《光谱学与光谱分析》《International Journal of Organic Chemistry》《Agricultural Biotechnology》《Journal of Chinese Pharmaceutical Sciences》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划宁德师专科研基金国家高技术研究发展计划更多>>

Discovery of novel sulfonamide substituted indolylarylsulfones as potent HIV-1 inhibitors with better safety profiles被引量：2: 《Acta Pharmaceutica Sinica B》2023年第6期2747-2764,共18页Shenghua Gao Letian Song Yusen Cheng Fabao Zhao Dongwei Kang Shu Song Mianling Yang Bing Ye Wei Zhao Yajie Tang Erik De Clercq Christophe Pannecouque Peng Zhan Xinyong Liu; financial support from Natural Science Foundation of China (81974507);Guangdong Basic and Applied Basic Research Foundation (2021A1515110740, China);China Postdoctoral Science Foundation (2021M702003);Shandong Province Natural Science Foundation for Youths (ZR2022QH036, China);the Foundation for Innovative Research Groups of State Key Laboratory of Microbial Technology (WZCX2021-03, China);Foreign cultural and educational experts Project (GXL20200015001, China);Science Foundation for Outstanding Young Scholars of Shandong Province (ZR2020JQ31, China);the Shandong Provincial Key research and development project (2019JZZY021011, China)。; Indolylarylsulfones(IASs) are classical HIV-1 non-nucleoside reverse transcriptase inhibitors(NNRTIs) with a unique scaffold and possess potent antiviral activity.To address the high cytotoxicity and improve safety pr...; 关键词：HIV-1 NNRTIS Indolylarylsulfone SULFONAMIDE CYTOTOXICITY

Effect of Artemisia annua L. as Substitute to Sulfonamides (Sodium Sulfadimerzine) on Coccidiosis and Growth Performance in Rabbits: 《Open Journal of Animal Sciences》2022年第2期159-170,共12页Hippolyte Mekuiko Watsop Djibrilla Nabilatou Jules Lemoufouet Ronald Vougat Ngom Emile Miegoue Mouchili Mama Mamoudou Abdoulmoumini Tendonkeng Fernand; Coccidiosis is a disease caused by protozoa of the genus Eimeria which seriously affects young rabbits. Treatment based on the use of anticoccidial drugs is increasingly ineffective due to the rapid emergence of resis...; 关键词：COCCIDIOSIS Rabbit Artemisia annua L. SULFONAMIDE Hydroethanolic Extract Anticoccidial Activity

Computer-Aid Design of Novel Sulfonamide Derivatives as EGFR Kinase Inhibitors for Cancer Treatment: 《International Journal of Organic Chemistry》2021年第4期171-186,共16页Souad Akili Djamila Ben Hadda Yasser Bitar Abdulkarim Najjar Mustapha Fawaz Chehna; Several novel sulfonamide-derivatives were designed and studied their physicochemical properties to develop novel kinase inhibitors. Therefore, molecular docking was performed for the designed compounds against epider...; 关键词：SULFONAMIDE ANTICANCER EGFR 2ITY KINASES Molecular Docking Molegro Virtual Docker MVD MarvinSketch

Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core: 《Acta Pharmacologica Sinica》2020年第3期293-302,共10页Jin-tao Wang Yue-ming Zheng Yue-ting Chen Min Gu Zhao-bing Gao Fa-jun Nan; This work was supported by the National Science Fund for Distinguished Young Scholars(81825021);the National Natural Science Foundation of China(81603096,81773707).; Nav1.7 channels are mainly distributed in the peripheral nervous system.Blockade of Nav1.7 channels with small-molecule inhibitors in humans might provide pain relief without affecting the central nervous system.Based...; 关键词：Nav1.7 sodium channel ARYL SULFONAMIDE maprotiline compound lOo ELECTROPHYSIOLOGY acetic acid-induced VISCERAL pain an algesic activity

GC-NICI-MS analysis of acetazolamide and other sulfonamide (R-SO2-NH2)drugs as pentafluorobenzyl derivatives [R-SO2-N(PFB)2] and quantification of pharmacological acetazolamide in human urine被引量：1: 《Journal of Pharmaceutical Analysis》2020年第1期49-59,共11页Olga Begou Kathrin Drabert Georgios Theodoridis Dimitrios Tsikas; Acetazolamide(molecular mass(MM),222)belongs to the class of sulfonamides(R-SO2-NH2)and is one of the strongest pharmacological inhibitors of carbonic anhydrase activity.Acetazolamide is excreted unchanged in the urin...; 关键词：ACETAZOLAMIDE Derivatization Quantification SULFONAMIDES Validation

Simultaneous Prediction of Retention Times and Peak Shapes of Sulfonamides in Reversed-Phase High-Performance Liquid Chromatography: 《Transactions of Tianjin University》2018年第3期256-262,共7页Xiaobing Wei Zhengji Pang Guoliang Fan Xinhua Xu Lihong Wang; supported by the National Nature Science Foundation of China (No. 51406109); In this paper, we propose a novelmethod based on the plate theory to simultaneously predict retention times and peak shapes under gradient elutions and different flow rates by reversed-phase high-performance liquid ch...; 关键词：Retention time Peak shape PREDICTION RP-HPLC SULFONAMIDE

Study on the dipeptide vinyl sulfonamide derivatives as proteasome inhibitor: 《Journal of Chinese Pharmaceutical Sciences》2016年第6期408-418,共11页姚书扬周玥; Natural Science Foundation of China for the financial support(Grant No.30772626); On the basis of the Michael-addition mechanism of classical proteasome inhibitors, six dipeptide vinyl sulfonamide and dipeptide vinyl sulfonate derivatives were designed and synthesized. Moreover, an efficient method...; 关键词：Proteasome inhibitor Dipeptide vinyl sulfonamides Wittig-Horner reaction g-Amino vinyl sulfonamide

Design, synthesis and biological evaluation of sulfonamide flavone derivatives as potential 20S proteasome inhibitors: 《Journal of Chinese Pharmaceutical Sciences》2014年第9期626-630,共5页杨冠宇孙琦王超梁磊许凤荣牛彦徐萍; The National Natural Science Foundation of China(Grant No.21202003);the National Basic Research Program of China(Grant No.2012CB518000);the Specialized Research Fund for the Doctoral Program of Higher Education of China(Grant No.20120001110010); A new series of sulfonamide flavone derivatives are designed as non-covalent inhibitors of proteasome assisted with computer-aided drug design （CADD）. The desired compounds were synthesized successfully and the biol...; 关键词：Sulfonamide flavone derivatives Non-covalent inhibitor CADD 20S proteasome inhibitor SELECTIVITY

Efficacy of Different Concentrations of Aloe chabaudii Leaf Gel as a Substitute for a Sulfonamide for the Control of Avian Coccidiosis: 《Open Journal of Applied Sciences》2013年第7期430-435,共6页Marvelous Sungirai Moses Mucheni Lawrence Masaka; The objective of this study was to investigate the effectiveness of Aloe chabaudii schonland juice as a potential substitute of sulphonamide drugs and to measure its effects when administered at different concentratio...; 关键词：ALOE chabaudii COCCIDIOSIS Sulphonamide EFFICACY

Evaluation of Anti-Oxidant Status and Radioprotective Activity of a Novel Anti-Cancer Drug in Mice: 《Journal of Cancer Therapy》2011年第5期616-628,共13页Raafat Yousri Eman Noaman Omama El Shawi Nadia Fahmy Maha Ghazy; Various approaches have been developed for diminishing the effects of radiation on normal tissues or enhancing tumor cell killing by ionizing radiation. Recently, there has been an increase in the interest in research...; 关键词：QUINOLINE SULFONAMIDE Derivative Whole Body γ-IR RADIOPROTECTOR Lipid PEROXIDATION Antioxidants Liver Enzymes Kidney Function HAEMATOLOGY

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