PHOTOSENSITIZERS

作品数：75被引量：147H指数：7
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Near-infrared organic photosensitizers with aggregation-induced emission and switchable fluorescence for fungal infection therapy
《Science China Chemistry》2025年第4期1426-1433,共8页Xinzhe Yang Zixuan Huang Keke Ding Huili Yang Lirong Wang Qing Xia Rong Hu Guang Shi Bingjia Xu Anjun Qin 
supported by the Natural Science Foundation of Guangdong Province of China(2023A1515010915,2024A1515010047);the Guangdong Provincial Key R&D Program-Nanotechnology Special Project(2023B0101200007).
The development of near-infrared(NIR)photosensitizers with aggregation-induced emission(AIE)properties;switchable luminescence colors;and satisfactory photodynamic therapy(PDT)effects on the treatment of fungal infect...
关键词：aggregation-induced emission near-infrared photosensitizers mechanochromism photodynamic therapy anti-C.albicans 
To activate a G protein-coupled receptor permanently with cell surface photodynamic action in the gastrointestinal tract
《World Journal of Gastroenterology》2025年第12期1-13,共13页Zong-Jie Cui 
Supported by the National Natural Science Foundation of China,No.32271278 and No.31971170.
Different from reversible agonist-stimulated receptor activation,singlet oxygen oxidation activates permanently G protein-coupled receptor(GPCR)cholecystokinin 1(CCK1R)in type II photodynamic action,with soluble photo...
关键词：Cholecystokinin 1 receptor Singlet oxygen G protein-coupled receptor activated by singlet oxygen Genetically encoded protein photosensitizers Calcium oscillations Pancreatic acinar cells 
Fighting hypoxia to improve photodynamic therapy-driven immunotherapy:Alleviating,exploiting and disregarding
《Chinese Chemical Letters》2025年第2期29-40,共12页Liangliang Jia Ye Hong Xinyu He Ying Zhou Liujiao Ren Hongjun Du Bin Zhao Bin Qin Zhe Yang Di Gao 
supported by the Qin Chuangyuan Traditional Chinese Medicine(TCM)and Innovation Research and Development Project of Shaanxi Provincial Administration of TCM(No.2022-QCYZH-017);Natural Science Foundation of Zhejiang Province(No.LY24E030010);Natural Science Foundation of Shaanxi Province(Nos.2022JM183,2024JC-YBMS-272);the Shaanxi Fundamental Science Research Project for Chemistry&Biology(No.22JHQ072);Shaanxi Provincial Key R&D Program(No.2022SF-342HZ);the Fundamental Research Funds for the Central Universities(Nos.xzy012022037,xzy012023002);the Postdoctoral Science Foundation of Shaanxi Province(No.2023BSHYDZZ05);Foundation by Shaanxi Provincial Administration of TCM(No.2021-ZZ-JC032)。
Innovative anti-cancer therapies that activate the immune system show promise in combating cancers resistant to conventional treatments.Photodynamic therapy(PDT)is one such treatment,which not only directly eliminates...
关键词：Photodynamic therapy Tumor hypoxia IMMUNOTHERAPY Immunogenic cell death PHOTOSENSITIZERS NANOMEDICINE 
Mechanism research of type I reactive oxygen species conversion based on molecular and aggregate levels for tumor photodynamic therapy
《Aggregate》2024年第6期214-223,共10页Youqin Xu Yili Xie Qing Wan Jianwen Tian Jing Liang Jianlong Zhou Mu Song Xinke Zhou Muzhou Teng 
Fundamental Research Funds for the Central Universities,Grant/Award Number:lzujbky-2022-50;Natural Science Foundation of Gansu Province,Grant/Award Number:23JRRA1518;Talent Innovation and Entrepreneurship Project of Lanzhou City,Grant/Award Number:2022-RC-49;Project of Gansu Provincial Department of Education,Grant/Award Number:2023QB-056;Natural Science Foundation of Jiangxi Province,Grant/Award Numbers:20224BAB214001,20232BAB203026;Provincial Talent Project of Gansu Province,Grant/Award Number:GZTZ2024-4;Talent Innovation and Entrepreneurship Project of Chengguan District,Grant/Award Number:2022-rc-7;National Natural Science Foundation of China,Grant/Award Number:22261035。
Type I photosensitizers(PSs)with the ability to generate reactive oxygen species(ROS)containing superoxide anion and hydroxyl radical have promising application potential for treating hypoxia tumors,but the deep mecha...
关键词：acid and protein responsive aggregation-induced emission PHOTOSENSITIZERS reactive oxygen species 
Microtubule polymerization induced by iridium-fullerene photosensitizers for cancer immunotherapy via dual-reactive oxygen species regulation strategy
《Aggregate》2024年第6期272-283,共12页Xiao-Xiao Chen Kun Peng Xi Chen Zheng-Yin Pan Qing-Hua Shen Yu-Yi Ling Jian-Zhang Zhao Cai-Ping Tan 
National Natural Science Foundation of China,Grant/Award Number:22177142;Basic and Applied Basic Research Foundation of Guangdong Province,Grant/Award Numbers:2022A1515111089,2023A1515010625,2024B1515040028。
Microtubules(MTs)are key players in cell division,migration,and signaling,and they are regarded as important targets for cancer treatment.In this work,two fullerene(C_(60))-functionalized Ir(Ⅲ)complexes(Ir-C_(60)1 an...
关键词：ANTICANCER FULLERENE iridium complexes MICROTUBULE photo-immunotherapy 
Mechanistic insights into intramolecular energy transfer dynamics in photosensitizers for triplet-triplet annihilation upconversion
《Chinese Journal of Chemical Physics》2024年第6期701-720,I0041,共21页Tingting Fu Yaxiong Wei Xinsheng Xu 
supported by the National Natural Science Foundation of China(No.22203004 and No.21927814);the Anhui Normal University 2023 Scholarship and Supplementary Discipline Construction Project(No.2023GFXK160).
Photosensitizers constitute a crucial element in the process of triplet-triplet annihilation upconversion,necessitating robust absorption of visible or near-infrared light,high intersystem crossing efficiency,prolonge...
关键词：Triplet-triplet annihilation upconversion Intramolecular singlet energy transfer Intramolecular triplet energy transfer PHOTOSENSITIZER 
Alkyl chain length-regulated in situ intelligent nano-assemblies with AIE-active photosensitizers for photodynamic cancer therapy
《Asian Journal of Pharmaceutical Sciences》2024年第6期84-100,共17页Lingyi Shen Qilong Zhang Yongchao Yao Yali Huang Zhichang Zheng Ming Li Hong Xu Lin Tan Xukun Liao Binyi Xia Lin Li Carl Redshaw Yang Bai Chengli Yang 
supported by the National Natural Science Foundation of China (81860543,32360237);Guizhou Provincial Science and Technology Projects (ZK[2023];Key Project 041,ZK[2021]076,[2019]2792 and[2018]5779-14);Guizhou Provincial Department of Education Foundation (KY[2022]229);Cultivation program of the Affiliated Hospital of Guizhou Medical University (gyfynsfc-2022-39);Cultivation program of the Guizhou Medical University (20NSP012);CR thanks the University of Hull for support
Photodynamic therapy(PDT)brings new hope for the treatment of breast cancer due to few side effects and highly effective cell killing;however,the low bioavailability of traditional photosensitizers(PSs)and their depen...
关键词：Aggregation-induced emission PHOTOSENSITIZERS Photodynamic therapy ROS generation Self-assembled nanoparticles 
Recent advances in biomimetic aggregation-induced emission photosensitizers for photodynamic therapy and immunotherapy
《BMEMat(BioMedical Engineering Materials)》2024年第3期74-91,共18页Shuai Guo Hui Tang Yahui Zhang Zhouyu Wang Swee Ching Tan 
Ministry of Education Academic Research Fund Tier 1,Grant/Award Number:A-0009304-00-00;Sichuan Science and Technology Program,Grant/Award Number:2022NSFSC1269。
The development of novel photosensitizers(PSs)with aggregation-induced emission(AIE)properties has emerged as a crucial advancement in the field of photodynamic therapy(PDT).However,the versatile applications of AIE P...
关键词：aggregation induced emission BIOMIMETIC IMMUNOTHERAPY photodynamic therapy PHOTOSENSITIZERS 
Construction of Type I Aggregation-Induced Emission Photosensitizers for Photodynamic Therapy via Photoinduced Electron Transfer Mechanism被引量：1
《有机化学》2024年第8期2530-2537,共8页Jia Hanyu Yu Yuewen Feng Guangxue Tang Ben Zhong 
广州市应用基础研究计划项目(No.2024A04J2466);国家自然科学基金委青年科学基金(No.22205067);广东省分子聚集发光重点实验室(No.2023B1212060003)资助项目。
Photodynamic therapy(PDT)as a non-invasive anticancer modality has received increasing attention due to its advantages of noninvasiveness,high temporospatial selectivity,simple and controllable operation,etc.PDT mainl...
关键词：photodynamic therapy aggregation-induced emission photoinduced electron transfer type I photosensitizer hypoxic tumor microenvironment 
Towards overcoming obstacles of type Ⅱ photodynamic therapy:Endogenous production of light,photosensitizer,and oxygen被引量：3
《Acta Pharmaceutica Sinica B》2024年第3期1111-1131,共21页Lin Yu Zhen Liu Wei Xu Kai Jin Jinliang Liu Xiaohui Zhu Yong Zhang Yihan Wu 
supported by the National Natural Science Foundation of China(32000036)。
Conventional photodynamic therapy(PDT)approaches face challenges including limited light penetration,low uptake of photosensitizers by tumors,and lack of oxygen in tumor microenvironments.One promising solution is to ...
关键词：Photodynamic therapy Cancer BIOGENESIS BIOSYNTHESIS Engineered bacteria PHOTOTHERAPY PHOTOSENSITIZERS CATALASE 
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