云南高校图书馆联盟文献共享服务平台- NUCLEOPHOSMIN

NUCLEOPHOSMIN: 作品数：18被引量：56H指数：5; 导出分析报告; 相关作者：李祺福石松林唐剑杨玲李晓更多>>; 相关机构：厦门大学中国科学院中山大学山西医科大学更多>>; 相关期刊：《Journal of Biophysical Chemistry》《Cancer Biology & Medicine》《Acta Biochimica et Biophysica Sinica》《中国细胞生物学学报》更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划湖南省卫生厅科研基金上海市科学技术发展基金更多>>

Pan-cancer analysis of the prognostic and immunological role of nucleophosmin/nucleoplasmin 3(NPM3)and its potential significance in lung adenocarcinoma被引量：1: 《Cancer Pathogenesis and Therapy》2023年第4期238-252,共15页Qianhui Wei Jing Zhou Xinyue Wang Zhaona Li Xiuqiong Chen Kaidi Chen Richeng Jiang; This study was supported by the National Natural Science Foundation of China(No.82172620);the Nature Science Foundation of Tianjin City(No.18JCZDJC98800).; Background Nucleophosmin/nucleoplasmin 3(NPM3),a member of the NPM protein family,is widely expressed in various human tissues.Although previous studies identified elevated NPM3 expression in several cancers,a systema...; 关键词：NPM3 Pan-cancerLung adenocarcinoma Prognosis Immune infiltration Biomarker

Nuclear PLD1 combined with NPM1 induces gemcitabine resistance through tumorigenic IL7R in pancreatic adenocarcinoma: 《Cancer Biology & Medicine》2023年第8期599-626,共28页Danqi Fu Jingrui Yan Zhaoyu Zhang Yang Liu Xiaoqing Ma Jinsheng Ding Shengyu Yang Ran Zhao Antao Chang Chuntao Gao Jing Liu Tiansuo Zhao Xiuchao Wang Chongbiao Huang Song Gao Ying Ma Bo Tang Yukuan Feng Hongwei Wang Jihui Hao; supported by the National Key Research and Development Program of China(Grant No.2021YFA1201100);the National Natural Science Foundation of China(Grant Nos.82103006,82030092,81720108028,82072657,82072716,82103003,82173295,81871968,81871978,82072691,and 82103222);the Tianjin Hygiene Healthy Science and Technology Project(Grant No.TJWJ2022MS007);the Science&Technology Development Fund of Tianjin Education Commission for Higher Education(Grant No.2020KJ141).; Objective:Pancreatic ductal adenocarcinoma(PDAC)is a highly malignant gastrointestinal cancer with a 5-year survival rate of only 9%.Of PDAC patients,15%-20%are eligible for radical surgery.Gemcitabine is an important...; 关键词：Gemcitabine resistance pancreatic ductal adenocarcinoma phospholipase D1 nucleophosmin 1 CRISPRa library

Long noncoding RNA LINC01088 inhibits esophageal squamous cell carcinoma progression by targeting the NPM1-HDM2-p53 axis被引量：2: 《Acta Biochimica et Biophysica Sinica》2023年第3期367-381,共15页Fan Liang Qiuli Luo Haibo Han Jianzhi Zhang Yue Yang Jinfeng Chen; supported by the grants from the National Natural Science Foundation of China(Nos.81773144 and 81772632);Capital Health Development Scientific Research Project(No.SF2018-2-2155);Science Foundation of Peking University Cancer Hospital(No.A002208).; Esophageal squamous cell carcinoma(ESCC)is characterized by extensive metastasis and poor prognosis.Long noncoding RNAs(lncRNAs)have been shown to play important roles in ESCC.However,the specific roles of lncRNAs in ...; 关键词：esophageal squamous cell carcinoma LINC01088 NUCLEOPHOSMIN P53

Tumor-associated autoantibodies are useful biomarkers in immunodiagnosis of α-fetoprotein-negative hepatocellular carcinoma被引量：9: 《World Journal of Gastroenterology》2017年第19期3496-3504,共9页Ting Wang Mei Liu Su-Jun Zheng Dan-Dan Bian Jin-Yan Zhang Jia Yao Qing-Fen Zheng A-Meng Shi Wen-Han Li Lu Li Yu Chen Jin-Hai Wang Zhong-Ping Duan Lei Dong; Supported by Clinical Research Cooperation Fund of the Capital Medical University,No.15JL67;Project of Science and Technology Development Plan of Beijing Municipal Education Commission,No.KM201610025021;High-Tech Personnel Training Program of Beijing Health System,No.2015-3-104;Beijing Municipal Science and Technology Commission,No.Z151100004015066;Shaanxi Science and Technology Coordination and Innovation Project,No.2016KTZDSF02-02; AIM To determine the prevalence and diagnostic value of autoantibodies inα-fetoprotein(AFP)-negative hepatocellular carcinoma(HCC).METHODS Fifty-six serum samples from AFP-negative HCC cases,86 from AFP-positive HCC ...; 关键词：α-fetoprotein Nucleophosmin 1 14-3-3zeta Mouse double minute 2 homolog IMMUNODIAGNOSIS AUTOANTIBODY Hepatocellular carcinoma

Nucleophosmin及notch1在肺腺癌中的表达及意义被引量：3: 《临床肺科杂志》2017年第2期207-211,共5页贺兼斌刘理静向志肖集文肖海波; 湖南省卫生厅科研基金(No B2013-157); 目的观察Nucleophosmin蛋白及notch1受体蛋白在肺腺癌组织中的表达并探讨其意义。方法选择2012,10-2015,06我院确诊的肺腺癌患者的肿瘤标本共107例,采用免疫组织化学染色方法检测Nucleophosmin蛋白和notch1受体蛋白质的表达情况。结果 N...; 关键词：NUCLEOPHOSMIN NOTCH1 肺腺癌转移

Proteomics Analysis of Up-regulated NPM1 Protein in Colorectal Cancer: 《Chemical Research in Chinese Universities》2016年第3期402-405,共4页WANG Hai HE Chengyan YANG Zhaowei GAO Shen LI Lingxia SUN Xiaoying FANG Ling LIU Ning LI Hongjun; Supported by the National Natural Science Foundation of China（Nos.81572082, 81472030, 20973074）, the Science Founda tion of Jilin Provincial Science＆Technology Department, China（No.2011713, 20130413017GH, 20150414015GH）, the Health and Family Planning Commission of Jilin Province, China（No.2015Z041） and the Scientific Support Project from Bethune Department of Jilin University, China（Nos.2012210, 2013207051）.; In order to identify potential protein targets involved in colorectal cancer（CRC）, we used a liquid chro- matography coupled with mass spectrometry（LC-MS）/MS-based proteomics approach to characterize global protei...; 关键词：Liquid chromatography-mass spectrometry（LC-MS） Colorectal cancer（CRC） Nucleophosmin I（NPM1）

姜黄素诱导人永生化表皮HaCaT细胞凋亡中Nucleophosmin的表达和定位变化: 《中国细胞生物学学报》2013年第6期780-785,共6页杨海波宋巍陈兰英李祺福于淮滨; 国家自然科学基金(批准号:30871241)资助的课题~~; 该文以姜黄素诱导处理前后的人永生化表皮HaCaT细胞为研究对象,对核仁磷酸蛋白(nucleophosmin,NPM)在核基质中存在、分布及其与凋亡相关基因产物在姜黄素处理前后HaCaT细胞中的共定位关系进行观察研究。Western blot结果显示,NPM存在于...; 关键词：NPM 人永生化表皮HaCaT细胞核基质细胞凋亡

New targets for the antitumor activity of gambogic acid in hematologic malignancies被引量：8: 《Acta Pharmacologica Sinica》2013年第2期191-198,共8页Li-jing YANG Yan CHEN; Gambogic acid （GA） is the main active ingredient of gamboge, a brownish to orange dry resin secreted from Garcinia hanburyi, a plant that is widely distributed in nature. Recent in vitro and in vivo studies have dem...; 关键词：gambogic acid hematological malignancies death inducer-obliterator HERG channel NUCLEOPHOSMIN NUCLEOPORIN steroidreceptor coactivator-3 reactive oxygen species

NucIeophosmin/B23对结肠癌侵袭能力的影响被引量：4: 《中国肿瘤临床》2012年第7期373-376,共4页刘岩张飞郭华张晓方张宁; 国家自然科学基金(编号:81001188)资助~~; 目的:探讨核仁磷酸蛋白(Nucleophosmin/B23)在人结肠癌组织中的表达及对人结肠癌细胞侵袭能力的影响。方法:选取2000年6月至2005年10月就诊于天津医科大学附属肿瘤医院结肠癌患者31例,并收集其肿瘤组织、对应的癌旁组织和转移淋巴结组织...; 关键词：NUCLEOPHOSMIN B23 结肠癌HCT116转移

Horizontal transfer of microRNAs: molecular mechanisms and clinical applications被引量：15: 《Protein & Cell》2012年第1期28-37,共10页Xi Chen Hongwei Liang Junfeng Zhang Ke Zen Chen-Yu Zhang; by grants from the National Natural Science Foundation of China(Nos.90813035,81101330,81171661,30890044,30772484,30725008,30890032,31071232,31000323,90608010,and J1103512);the Natural Science Foundation of Jiangsu Province(No.BK2011013);the Fundamental Research Funds for the Central Universities(No.1107020839).; A new class of RNA regulatory genes known as microRNAs(miRNAs)has been found to introduce a whole new layer of gene regulation in eukaryotes.The intensive studies of the past several years have demonstrated that miRNA...; 关键词：MICRORNA extracellular microRNA microRNA secretion horizontal transfer MICROVESICLE EXOSOME apoptotic body high-density lipoprotein Argonaute 2 nucleophosmin 1 diagnosis therapy

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