GLUTATHIONE-S-TRANSFERASE

作品数：26被引量：35H指数：3
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相关领域：医药卫生更多>>
相关作者：王帅李祥瑞更多>>
相关机构：南京农业大学更多>>
相关期刊：《Chinese Journal of Cancer Research》《Progress in Natural Science:Materials International》《Journal of Agricultural Science and Technology(A)》《Asian Pacific Journal of Tropical Biomedicine》更多>>
相关基金：国家自然科学基金江苏高校优势学科建设工程资助项目公益性行业(农业)科研专项更多>>
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Modification of the Genetic Polymorphism of Glutathione-S-Transferase (GSTM1 and GSTT1) in Motorcycle Drivers Exposed to BTEX in Cotonou
《Journal of Biosciences and Medicines》2022年第11期104-112,共9页Cachon Fresnel Boris Sagbo H. Firmin Nanoukon Chimène Djedatin Gustave Atindehou Ménonvè Senou Maximin Ayi-Fanou Lucie 
The glutathione-S-transferase genes mainly the GSTM1 and GSTT1 alleles are responsible for the synthesis of detoxication enzymes that can remove toxic substances. The objective of this study is to seek changes in the ...
关键词：BTEX GLUTATHIONE-S-TRANSFERASE Deletion PCR Motorcycle Drivers 
Glutathione-S-transferases genes-promising predictors of hepatic dysfunction被引量：4
《World Journal of Hepatology》2021年第6期620-633,共14页Vasyl Prysyazhnyuk Larysa Sydorchuk Ruslan Sydorchuk Iryna Prysiazhniuk Kateryna Bobkovych Inna Buzdugan Valentina Dzuryak Petro Prysyazhnyuk 
diseases pathogenesis are genes that encodes the synthesis of glutathione-Stransferase(GST),known as the second phase enzyme detoxification system that protects against endogenous oxidative stress and exogenous toxins...
关键词：GLUTATHIONE-S-TRANSFERASE Non-alcoholic fatty liver disease Drug induced liver disease Liver cirrhosis 
Prognostic Significance of Comparison of Clinical Indicators with Manifestations of Genetic Polymorphism of Glutathione-S-Transferases in Non-Small Cell Lung Cancer被引量：1
《Journal of Cancer Therapy》2018年第12期962-973,共12页Mikhail N. Shapetska Evelina V. Krupnova Alena P. Mikhalenka Natalia V. Chebotareva Anna N. Shchayuk Svetlana G. Pashkevich Alexander V. Prokhorov 
The article presented the results of comparison of polymorphic variants of the genes GSTM1, GSTT1, GSTP1 and clinical manifestations of non-small cell lung carcinoma. The association of the genotype GSTT1 (del) with t...
关键词：SQUAMOUS Cell Lung Carcinoma ADENOCARCINOMA GLUTATHIONE-S-TRANSFERASE Survival Rate 
Possible association of a distinct combined Glutathione-S-transferase members with allergic asthma patients in Pakistan
《Genes & Diseases》2017年第2期111-115,共5页Aamna Dar Rani Faryal Nosheen Masood 
Allergic asthma is a diverse chronic respiratory disease characterized by the inflammation of the lower airway disease affecting many people around the world with rising morbidity and mortality.Association between ast...
关键词：Allergic asthma Genetic polymorphism GSTM GSTT GST deletions MUTATIONS 
Pistacia chinensis:Strong antioxidant and potent testicular toxicity amelioration agent被引量：1
《Asian Pacific Journal of Tropical Medicine》2017年第4期359-369,共11页Farah Noureen Muhammad Rashid Khan Naseer Ali Shah Rahmat Ali Khan Kiran Naz Saadia Sattar 
Objective:To evaluate in ritro and in riro antioxidant potency of Pistacia chinensis(P.chinensis) bark and leaves extracts along with its protective role against CCl_4 induced toxicity in testis of the rat.Methods Var...
关键词：Pislacia chinensis Plasma testosterone GLUTATHIONE-S-TRANSFERASE Antioxidant enzymes 
Obesity and diabetes accelerate hepatocarcinogenesis via hepatocyte proliferation independent of NF-κB or Akt/mTORC1被引量：1
《Journal of Clinical & Translational Research》2016年第1期27-38,共12页Evi Arfianti Claire Z Larter Seungsoo Lee Vanessa Barn Geoffrey Haigh Matthew M.Yeh George NIoannou Narci C.Teoh Geoffrey C.Farrell 
Background:There are strong links between obesity,diabetes and hepatocellular carcinoma(HCC),but molecular mechanisms remain unclear.Aim:We tested the proposed involvement of NF-κB,IL-6/STAT3 and Akt/mTORC1 before on...
关键词：ATAXIA-TELANGIECTASIA mutated GLUTATHIONE-S-TRANSFERASE pi RAPAMYCIN INTERLEUKIN-6 signal transducer and activator of transcription3 
Natural Products Modulate the Multifactorial Multidrug Resistance of Cancer被引量：1
《Pharmacology & Pharmacy》2015年第3期146-176,共31页Safaa Yehia Eid Mahmoud Zaki El-Readi Sameer Hassan Fatani Essam Eldin Mohamed Nour Eldin Michael Wink 
Multidrug resistance (MDR) is a critical problem in cancer chemotherapy. Cancer cells can develop resistance not only to a single cytotoxic drug, but also to entire classes of structurally and functionally unrelated c...
关键词：MULTIDRUG Resistance (MDR) ABC-Transporters (ABCT) Metabolic ENZYMES Apoptosis CytochromeP3A4 (CYP3A4) GLUTATHIONE-S-TRANSFERASE (GST) 
Induction of Phase II Enzymes Glutathione-S-Transferase and NADPH: Quinone Oxydoreductase 1 with Novel Sulforaphane Derivatives in Human Keratinocytes: Evaluation of the Intracellular GSH Level
《Pharmacology & Pharmacy》2014年第10期937-943,共7页Sohely Sikdar Benjamin Lallemand Jacques Dubois 
Phase II enzymes including NADPH: Quinone Oxydoreductase 1 (NQO1) and Glutathione-S-Transferase (GST) represents a major and natural cellular protection system against deleterious environmental factors which cause ski...
关键词：Phase 2 GLUTATHIONE SULFORAPHANE KERATINOCYTES 
Pharmacogenetics of azathioprine in inflammatory bowel disease: A role for glutathione-S-transferase?被引量：2
《World Journal of Gastroenterology》2014年第13期3534-3541,共8页Gabriele Stocco Marco Pelin Raffaella Franca Sara De Iudicibus Eva Cuzzoni Diego Favretto Stefano Martelossi Alessandro Ventura Giuliana Decorti 
Azathioprine is a purine antimetabolite drug commonly used to treat inflammatory bowel disease (IBD). In vivo it is active after reaction with reduced glutathione (GSH) and conversion to mercaptopurine. Although this ...
关键词：Inflammatory bowel disease AZATHIOPRINE PHARMACOGENETICS GLUTATHIONE-S-TRANSFERASE Pediatric patients 
Carboxylesterase and Glutathione-S-Transferase （GST＇s） Induced Resistance to Bacillus thuringiensis Toxin CrylAb in Rice Leaf Folder, Cnaphalocrocis medinalis （Guenee） Populations
《Journal of Agricultural Science and Technology(A)》2013年第1期53-59,共7页Veegala Ramesh Babu Vemuri Shashi Bhushan Chintalapati Padmavathy: Muthugonder Mohan SenaMahendran. Balachandran Bellamkonda Ramesh 
The rice leaf folder （RLF）, Cnaphalocrocis medinalis （Guenee） （lnsecta： Lepidoptera： Pyralidae）, is an important pest, widely distributed in many rice growing areas of Asia. The over-use of broad-spectrum chem...
关键词：Cnaphalocrocis medinalis carboxylesterase and glutathione-s-transferase ISOZYMES B type esterases. 
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