Parkinson’s disease is chara cterized by the loss of dopaminergic neurons in the substantia nigra pars com pacta,and although restoring striatal dopamine levels may improve symptoms,no treatment can cure or reve rse ...
supported by Linea D.1.2021 UniversitàCattolica del S.Cuore(to MTV);by the Italian Ministry of Health(IT)[Research Grant:RF-2018-12365527,to MDA and MTV];supported by the American Alzheimer’s Association[AARG-21-851219];by Fondazione Roma(Rome,Italy)。
Since their first description in the brains of patients suffering from Alzheimer ’s disease(AD), more than 100 years ago, extracellular amyloid-β(Aβ) plaques and intracellular neurofibrillary tangles have been the ...
supported by the Japan Society for the Promotion of Science,Tokyo,Japan;Grant No.23890054 and 25861361
Children are being exposed to an increasingly greater variety of anesthetics with advances in pediatric and obstetric surgery. Recent animal and retrospective human data suggest that the general anes- thetics commonly...
Chronic traumatic encephalopathy(CTE)is a chronic neurodegenerative disease featured with tauopathy.CTE is tightly related with repetitive mild traumatic brain injury(m TBI),which is interchangeably known as concu...
the National Natural Science Foundation of China, No. 30660231
Rats were subjected to unpredictable chronic stress and isolation-induced depression, and were then intragastrically perfused with Jieyu No.1 decoction or amitriptyline water solution for 21 consecutive days. Open-fie...
the National Natural Science Foundation of China,No. 81171707;the Major State Basic Research Program of China,No.2012CB933600;Shanghai Pujiang Program,No.11PJD016;China Postdoctoral Science Foundation,No. 20090460629;Fund for Key Disciplines of Shanghai Municipal Education Commission,No.J50206
A rat model of extra-vertebral foramen cervical nerve entrapment was established according to the following parameters: stimulation intensity 20 V; frequency 50 Hz; pulse width 200 μs; duration 333 ms/s for a total ...
the National Natural Science Foundation of China,No.30960393;Key Foundation in Science and Technology of Xinjiang Uygur Autonomous Region,No.200633128(2);the Youth Science and Technology Foundation of Health Department of Xinjiang Uygur Autonomous Region,No.2007Y26
BACKGROUND: Neonatal cerebral palsy is mainly caused by prenatal factors. At present, an animal model of prenatal infection and early postnatal hypoxia does not exist. OBJECTIVE: To observe morphology and motor perf...
Previous studies have demonstrated that the cholinergic system, via nicotinic receptors, regulates intracellular free calcium levels in the facial nucleus under normal physiological conditions. However, the regulation...
a Grant from Health Department of Guangdong Province in China,No. A2007169
BACKGROUND: Animal models of brachial plexus root avulsion are required for the study of brachial plexus root injuries. The established ventral approach results in slight injuries, and is similar to mechanisms underl...
the National Natural Science Foundation of China,No.30271333
BACKGROUND: An animal model of chronic optic nerve injury is necessary to further understand the pathological mechanisms involved. OBJECTIVE: To establish a stabilized, chronic, optic nerve crush model, which is sim...