Background:In the last decade,a varied prevalence of lifestyle-mediated health ailments ranging from infectious disorders to non-curable diseases has been observed.Globally the stone formation(lithiasis)in human kidne...
Background:Cyclosporine A (CsA) is a commonly used clinical immunosuppressant.However,CsA exposure in rabbits during the gestation period was shown to cause a postnatal decrease in the number of nephrons,with the e...
Supported by National Institutes of Health,No.DP2 OD008470;the University of Notre Dame College of Science and Graduate School;a generous donation to support stem cell research provided by the Gallagher Family
Kidney disease is a devastating condition that affects millions of people worldwide, and its prevalence predicted to significantly increase. The kidney is complex organ encompassing many diverse cell type organized in...
Supported by Grants-in-Aid for Young Scientists(B)(No.15K18454 to Tsujimura T);Scientific Research(B)(No.15H03001 to Hishikawa K);Scientific Research(C)(Nos.25461208 to Takase O,15K09244 to Yoshikawa M and 26462400 to Idei M)from the Japan Society for the Promotion of Science
The gene encoding bone morphogenetic protein-7(BMP7) is expressed in the developing kidney in embryos and also in the mature organ in adults. During kidney development, expression of BMP7 is essential to determine the...
Supported by National Institutes of Health,No.DP2 OD008470;Private funding was provided from the University of Notre Dame College of Science and Graduate School;a generous donation to support stem cell research provided by the Gallagher Family
Kidney disease is an escalating global health problem,for which the formulation of therapeutic approaches using stem cells has received increasing research attention.The complexity of kidney anatomy and function,which...
AIM:To review an evolution of laparoscopic surgery,there has been a growing interest in laparoendoscopic single-site surgery(LESS).METHODS:A comprehensive electronic literature search was conducted using PubM ed datab...
Objective: To examine the effect of warm and cold ischemia on functions of the operated kidney in cases with a normal contralateral kidney undergoing nephron sparing surgery. Methods: This study enrolled 40 patients w...
This study was supported by a grant from the Doctoral Foundation of Shanghai Jiaotong University Medical School(No.BXJ0615)
Von Hippel-Lindau (VHL) disease is a rare autosomal dominant disorder caused by germ line mutations of the VHL tumour suppressor gene. it predisposes affected individuals to develop a variety of neoplasms, including...
Objective: To observe the change of nephron damaged by chemotherapy and to evaluate the effect of Baoshen Mixture (保肾合剂, BSM) in protecting and treating damaged nephrons. Methods: Four hundred tumor patients w...