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Advanced nanomedicines and immunotherapeutics to treat respiratory diseases especially COVID-19 induced thrombosis: 《World Journal of Clinical Cases》2024年第16期2704-2712,共9页Jie Wu Ying Zheng Li-Na Zhang Cai-Li Gu Wang-Li Chen Min-Qiang Chang; Immunotherapy and associated immune regulation strategies gained huge attraction in order to be utilized for treatment and prevention of respiratory diseases.Engineering specifically nanomedicines can be used to regul...; 关键词：NANOMEDICINES IMMUNOTHERAPEUTICS Respiratory diseases COVID-19 THROMBOSIS

Combatting Pathogenic Bacteria with Synthetic Immunotherapeutics from Chitosan:Antibody Recruiting at Engineered Bacterial Surface with Peptidoglycan Analogs: 《CCS Chemistry》2024年第6期1448-1457,共10页Yuan Xu Shihao Song Hongwei Duan Yinyue Deng Xue-Wei Liu; the Ministry of Education(grant nos.MOET2EP30120-0007 and MOE2018-T2-2-128);the National Research Foundation(grant no.NRF-CRP22-2019-0002);Agency for Science,Technology and Research(A*STAR);Singapore(grant no.A20E5c0087);the National Natural Science Foundation of China(grant no.32300033);the Scientific Research Foundation of Hainan University(grant nos.KYQD(ZR)-22173 and KYQD(ZR)-23006).; The emergence of microbial drug resistance,coupled with the paucity of new antibiotics poses an impending threat to public health.In this work,we drew inspiration from synthetic peptidoglycan oligomers and successfull...; 关键词：CHITOSAN bacterial infection endogenous antibodies bacterial surface engineering peptidoglycan analogs

Author correction to‘Co-delivery of nigericin and decitabine using hexahistidine-metal nanocarriers for pyroptosis-induced immunotherapeutics’[Acta Pharm Sin B 12(2022)4458–4471]: 《Acta Pharmaceutica Sinica B》2024年第5期2359-2360,共2页Qiang Niu Yu Liu Yujing Zheng Ziwei Tang Yuna Qian Ruogu Qi Jianliang Shen Ping Zhao; The authors regret that there is an error in Fig.6 in the article due to the mistake of copying and pasting in the process of assemblingﬁgures and negligence in the proofreading.Although it does not affect the conclus...; 关键词：journal CORRECTION conclusion

Co-delivery of nigericin and decitabine using hexahistidine-metal nanocarriers for pyroptosis-induced immunotherapeutics被引量：5: 《Acta Pharmaceutica Sinica B》2022年第12期4458-4471,共14页Qiang Niu Yu Liu Yujing Zheng Ziwei Tang Yuna Qian Ruogu Qi Jianliang Shen Ping Zhao; This work was financially supported by the National Nature Science Foundation of China(No.21671150,52073145,21877084);the Key Research Projects of Guangdong Province(NO.2021ZDZX4019).; Pyroptosis provides a new window for relieving the tumor immunosuppressive microenvironment(TIM)and promoting systemic immune responses for tumor treatments.However,gasdermin D(GSDMD),a key protein in the pyroptosis p...; 关键词：Self-assembled nanoparticle PYROPTOSIS NLRP3 GSDMD Inflammation IL-8 Immunotherapy responses Solid tumor

Therapeutics to harness the immune microenvironment in multiple myeloma: 《Cancer Drug Resistance》2022年第3期647-661,共15页James J.Ignatz-Hoover James J.Driscoll; supported by NIH R01(5R01AI139141 to JJD),University Hospitals Cleveland Medical Center/Seidman Cancer Center,and the Case Comprehensive Cancer Center.; Multiple myeloma(MM)remains an incurable,genetically heterogeneous disease characterized by the uncontrolled proliferation of transformed plasma cells nurtured within a permissive bone marrow(BM)microenvironment.Curre...; 关键词：Multiple myeloma drug resistance proteasome inhibitors IMMUNOMODULATORS IMMUNOTHERAPEUTICS adaptive resistance bone marrow microenvironment

Expanded Scope of Bacillus Calmette-Guerin(BCG)Vaccine Applicability in Disease Prophylaxis,Diagnostics,and Immunotherapeutics: 《Infectious Microbes & Diseases》2020年第4期144-150,共7页Oluwafolajimi A.Adesanya Christabel I.Uche-Orji Yeshua A.Adedeji John I.Joshua Adeniyi A.Adesola Chibuike J.Chukwudike; Following the discovery of the Bacillus Calmette-Guerin(BCG)vaccine,its efficacy against Mycobacterium tuberculosis was soon established,with several countries adopting universal BCG vaccination schemes for their popu...; 关键词：BCG AUTOIMMUNITY IMMUNOTHERAPEUTICS complications non-specific effects

Nanomedicine-mediated alteration of the pharmacokinetic profile of small molecule cancer immunotherapeutics被引量：2: 《Acta Pharmacologica Sinica》2020年第7期881-894,共14页Simon Van Herck Bruno G.De Geest; The advent of immunotherapy is a game changer in cancer therapy with monoclonal antibody-and T cell-based therapeutics being the current flagships.Small molecule immunotherapeutics might offer advantages over the biol...; 关键词：cancer immunotherapy small molecule drugs pharmacokinetic profile NANOMEDICINE toll-like receptors stimulator of interferon genes(STING)

COVID-19:immunopathogenesis and Immunotherapeutics被引量：27: 《Signal Transduction and Targeted Therapy》2020年第1期1327-1334,共8页Li Yang Shasha Liu Jinyan Liu Zhixin Zhang Xiaochun Wan Bo Huang Youhai Chen Yi Zhang; supported by grants from the Emergency Prevention and Control of COVID-19 Project of Henan Province(grant no.201100310900);the 2020 Science and Technology Project of Henan Province(grant no.202102310039);the National Natural Science Foundation of China(grant nos.91942314,U1804281,81602024);the State’s Key Project of Research and Development Plan(grant nos.2018YFC1313400,2016YFC1303500)。; The recent novel coronavirus disease(COVID-19)outbreak,caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is seeing a rapid increase in infected patients worldwide.The host immune response to SARS-C...; 关键词：PATHOGENESIS IMMUNITY CLINICAL

Novel Immunotherapeutics Summit 2014: 《中国现代神经疾病杂志》2013年第12期1056-,共1页; Time:January 29-31,2014Venue:San Diego,USA Website:www.ecco-org.eu/Global/Events/Other-Events/Novel-Immunotherapeutics-Summit-2014.aspx The Novel Immunotherapeutics Summit 2014 brings together experts from academia an...; 关键词：WWW Novel Immunotherapeutics Summit 2014

Novel Immunotherapeutics Summit 2014: 《中国现代神经疾病杂志》2013年第11期930-,共1页; Time:January 29-31,2014Venue:San Diego,USA Website:www.ecco-org.eu/Global/Events/Other-Events/Novel-Immunotherapeutics-Summit-2014.aspx The Novel Immunotherapeutics Summit 2014 brings together experts from academia an...; 关键词：WWW WILL Novel Immunotherapeutics Summit 2014

IMMUNOTHERAPEUTICS