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作品数:34被引量:274H指数:9
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相关领域:医药卫生更多>>
相关作者:金哲虎南美兰金承龙张季郝敏更多>>
相关机构:延边大学医学院附属医院上海上药华宇药业有限公司南京中医药大学更多>>
相关期刊:《Hepatobiliary & Pancreatic Diseases International》《Chinese Medical Journal》《实用医学杂志》《Journal of Biosciences and Medicines》更多>>
相关基金:国家自然科学基金中国博士后科学基金江苏省高校自然科学研究项目国家中医药管理局度中医药行业科研专项更多>>
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Threshold-Effect Associations of Serum 25- hydroxyvitamin D on Bone Turnover Markers and GC rs2282679 Variants in Chinese Women of Childbearing Age
《Biomedical and Environmental Sciences》2025年第4期433-446,共14页Xiaoyun Shan Yuting Li Xiayu Zhao Yichun Hu Siran Li Huidi Zhang Yang Cao Rui Wang Lichen Yang 
Objective This study aimed to investigate possible serum 25-hydroxyvitamin D[25(OH)D]cutoffs for the associations between 25(OH)D and Bone turnover markers(BTMs),and how GC gene variation influences such cutoffs in Ch...
关键词:25-hydroxyvitamin D OSTEOCALCIN Procollagen type 1 N-terminal propeptide β-CrossLaps of type 1 collagen containing cross-linked C-telopeptide Gene polymorphism 
Influence of serum adiponectin level and SNP +45 polymorphism of adiponectin gene on myocardial fibrosis被引量:4
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2013年第8期721-728,共8页Cheng-jun YAN Su-mei LI Qiang XIAO Yan LIU Jian HOU Ai-fang CHEN Li-ping XIA Xiu-chang LI 
Project supported by the Natural Science Foundation of Shandong Province, China (No. ZR2012HL19);the Science and Technology Development Plan of Tai’an City, China (No. 20113096)
Adiponectin plays an important role in the development of hypertension, atherosclerosis, and cardio- myocyte hypertrophy, but very little was known about the influence of serum adiponectin or the adiponectin gene poly...
关键词:Hypertension Myocardial fibrosis Adiponectin gene Type-Ⅰ procollagen carboxyl end peptide (PICP) Type-Ⅲ procollagen ammonia cardinal extremity peptide (PIIINP) 
Colchicine reduces procollagen Ⅲ and increases pseudocholinesterase in chronic liver disease被引量:14
《World Journal of Gastroenterology》2010年第23期2889-2894,共6页Sergio Muntoni Marcos Rojkind Sandro Muntoni 
AIM:To test whether colchicine would be an effective antif ibrotic agent for treatment of chronic liver diseases in patients who could not be treated with α-interferon.METHODS:Seventy-four patients(46 males,28 female...
关键词:Chronic liver disease COLCHICINE Liver cirrhosis Liver fibrosis Type  procollagen peptide 
SERUM CONCENTRATIONS OF HYALURONIC ACID, PROCOLLAGEN TYPE III NH_2-TERMINAL PEPTIDE, AND LAMININ IN PATIENTS WITH CHRONIC CONGESTIVE HEART FAILURE被引量:14
《Chinese Medical Sciences Journal》2006年第3期175-178,共4页Gang Li Qing-bo Yan Liang-ming Wei 
Objective To explore the role of serum fibrotic indices including hyaluronic acid (HA), procollagen type Ⅲ NH2-terminal peptide (PCIIIP), and laminin (LN) in assessing the severity of myocardial fibrosis in chr...
关键词:congestive heart failure hyaluronic acid procollagen type  NH2-terminal peptide LAMININ 
Effect of Astragalus complanatus flavonoid on anti-liver fibrosis in rats被引量:8
《World Journal of Gastroenterology》2005年第37期5782-5786,共5页Chun-Yu Liu Zhen-Lun Gu Wen-Xuan Zhou Ci-Yi Guo 
AIM: To observe the anti-liver fibrosis effect of Astragalus complanatus fiavonoids (ACF) in rats. METHODS: The liver fibrosis model in rats was established by injecting interperitoneally 0.2 mL/100 g 0.5% dimethy...
关键词:Astragalus complanatus  Liver fibrosis N-propeptide of typeⅠ procollagen N-propeptide of type  procollagen Malondialdehyde Superoxide dismutase Matrix metal protease-1 Tissue inhibitor of metal protease-1 
Leptin administration exacerbates thioacetamide-induced liver fibrosis in mice被引量:9
《World Journal of Gastroenterology》2005年第31期4822-4826,共5页Kai Dai Jun-Ying Qi De-Ying Tian 
AIM: To investigate the effects of leptin administration on liver fibrosis induced by thioacetamide (TAA). METHODS: Twenty-four male C57BI/6 mice were randomly allocated into four groups, which were intra-peritone...
关键词:Liver fibrosis LEPTIN α1(I) procollagen 
Effects of adrenomedullin gene overexpression on biological behavior of hepatic stellate cells被引量:3
《World Journal of Gastroenterology》2005年第23期3549-3553,共5页YiWang Jin-ShengZhang Guang-CunHuang QiCheng Zhong-HuaZhao 
Supported by the National Natural Scientific Foundation of China,No.30170417
AIM: To investigate the effects of adrenomedullin (AM) gene overexpression on the biological characteristics of human hepatic stellate cells (hHSCs) by stable transfection.METHODS: hHSCs which express low basal levels...
关键词:ADRENOMEDULLIN Hepatic stellate cell Procollagen type  and  
The Level of Serum Intact Terminal Peptide of Procollagen and Its Clinical Significance in Patients with Chronic Keshan Disease
《South China Journal of Cardiology》2005年第1期38-41,共4页马宾 牛小麟 董新 任付先 
Objectives To evaluate the changes of serum intact terminal peptide of procollagen in patients with chronic Keshan disease (KD) and investigate their clinical significance. Methods The concentrations of serum intact N...
关键词:Keshan disease Intact terminal peptide of procollagen Myocardial fibrosis Cardiac function 
Changes in myocardial collagen content before and after left ventricular assist device application in dilated cardiomyopathy被引量:3
《Chinese Medical Journal》2004年第3期401-407,共7页梁红 Johannes Müller 翁渝国 Gerd Wallukat 付平 林汉生 Sabina Bartel Christoph Knosalla Reinhard Pregla Roland Hetzer 
BACKGROUND: The purposes of this study were to confirm the changes in myocardial collagen level after left ventricular assist device (LVAD) support in dilated cardiomyopathy (DCM), find the relation between these chan...
关键词:Heart-Assist Devices Adult Cardiomyopathy  Dilated Collagen Comparative Study Female Heart Transplantation Humans HYDROXYPROLINE Male Middle Aged MYOCARDIUM PROCOLLAGEN Prognosis 
Serum hyaluronic acid, procollagen type Ⅲ and Ⅳ in histological diagnosis of liver fibrosis被引量:11
《Hepatobiliary & Pancreatic Diseases International》2003年第1期69-72,共4页Shi-Bin Xie Ji-Lu Yao Rong-Qin Zheng Xiao-Mou Peng Zhi-Liang Gao the Department of Infectious Diseases, Third Affiliated Hospital, Zhongshan University, Guangzhou 510630, China , 
This study was supported by the grant from the Guangdong Provincial Science and Technology Foundation (No. A 1999--198).
OBJECTIVE: To assess the significance of serum hyaluronic acid (HA), proeollagen type Ⅲ (PCⅢ), collagen type Ⅳ (CⅣ) in the histological diagnosis of liver fibrosis. METHODS: The concentrations of serum HA, PCⅢ, C...
关键词:hyaluronic acid procollagen type  collagen type  hepatic fibrosis DIAGNOSIS liver histology 
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