LIMONOIDS

作品数：29被引量：35H指数：3
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相关领域：医药卫生轻工技术与工程更多>>
相关作者：杨秀伟滕杰更多>>
相关机构：北京大学更多>>
相关期刊：《Agricultural Sciences》《Journal of Chinese Pharmaceutical Sciences》《Chinese Journal of Chemistry》《Natural Products and Bioprospecting》更多>>
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Structurally Diverse Limonoids from Trichilia connaroides and Their Antitumor Activities
《Chinese Journal of Chemistry》2024年第24期3567-3580,共14页Ying Yan Dan Wang Fang-Jiao Zhou Yu-Han Zhao Xu-Jie Qin Yu Zhang Xiao Ding Xiao-Jiang Hao 
Financial support for this study was provided by National Natural Science Foundation of China(82360687);Guizhou Provincial Science and Technology Project(ZK[2022]393);Key Research and Development Project of Yunnan Province(202203AC100009,202003AD150012);Project of Yunnan Characteristic Plant Screening and R&D Service CXO Platform(2022YKZY001).
Twelve new limonoids(1—12),named trichilitins A—L,were isolated from the leaves and twigs of Trichilia connaroides,together with ten known compounds(13—22).The structures were elucidated by extensive spectroscopic ...
关键词：Natural products LIMONOIDS MELIACEAE Structure elucidation Trichilia connaroides Antitumor activities p53 and p21 Structure-activity relationships Cancer treatment 
Five new limonoids isolated from Walsura robusta
《Natural Products and Bioprospecting》2023年第1期657-664,共8页Li Hou Cui-Xuan Mei Chun-Mao Yuan Gui-Hua Tang Duo-Zhi Chen Qing Zhao Hong-Ping He Ming-Ming Cao Xiao-Jiang Hao 
the National Natural Science Foundation of China(U1812403 to X.-J.Hao and 22177050 to M.Cao);Project of Yunnan Characteristic Plant Screening and R&D Service CXO Platform(2022YKZY001);Foundation of Central Asian Drug Discovery and Development Center of Chinese Academy of Sciences(CAM202103,China);Youth Innovation Promotion Association CAS to M.Cao(2022-2026).
Five new toosendanin limonoids with highly oxidative furan ring walsurobustones A-D(1-4),and one new furan ring degraded limonoid walsurobustone E(5)together with one known compound toonapubesic acid B(6)were isolated...
关键词：LIMONOIDS Tetranortriterpenoids Walsura robusta CYTOTOXICITY 
Molecular docking study of xylogranatins binding to glycogen synthase kinase-3β
《Digital Chinese Medicine》2022年第1期9-17,共9页Christian Baillya Gérard Vergoten 
Objective The mangrove tree Xylocarpus granatum J.Koenig(X.granatum)is a medicinal plant used to treat various diseases in several Asian countries.Many bioactive natural products have been isolated from the plants,par...
关键词：Natural products Xylocarpus granatum Xylogranatins Glycogen synthase kinase-3β(GSK-3β) LIMONOIDS CANCER Molecular modelling Structure-activity relationship 
Mufolinin A,an unprecedented ring A-seco 10-ethyllimonoid from Munronia unifoliolata被引量：1
《Chinese Chemical Letters》2022年第1期516-518,共3页Yunpeng Sun Letian Cui Qiurong Li Pengfei Tang Yongyi Li Wenjun Xu Jun Luo Lingyi Kong 
supported by the National Natural Science Foundation of China(No.31470416);the 111 Project from Ministry of Education of China and the State Administration of Foreign Export Affairs of China(No.B18056).ll supported in part by SciGrid,Chinese Academy of Sciences。
Mufolinin A(1),a ring A-seco rearranged limonoid with an unprecedented ethyl at C-10 and novel 6/6/6/5 fused-ring skeleton,together with three new potential precursors(ring A-seco limonoids,2–4)were isolated from Mun...
关键词：MELIACEAE Munronia unifoliolata LIMONOIDS ANTI-INFLAMMATORY Anti-multidrug resistance 
Diverse Ring-seco Limonoids from Munronia unifoliolata and Their Biological Activities被引量：2
《Chinese Journal of Chemistry》2022年第1期123-136,共14页Yunpeng Sun Qiurong Li Letian Cui Pengfei Tang Yongyi Li Lingyi Kong Jun Luo 
sponsored by the National Natural Science Foundation of China(31470416);the 111 Project from Ministry of Education of China;the State Administration of Foreign Export Affairs of China(B18056).
Twenty-two new limonoids,mufolinoids A—V(1—22),including six rings A,B-seco limonoids(1—6),twelve ring A-seco limonoids(7—18),four ring-intact limonoids(19—22),together with thirteen known compounds(23—35)were i...
关键词：Munronia unifoliolata LIMONOIDS Structure elucidation Inflammatory Natural products 
Four New Limonoids from the Barks of Toona ciliata
《Natural Products and Bioprospecting》2021年第1期81-86,共6页Pan-Pan Zhang Yun-Ge Bu Shang Xue Zhi-Rong Cui Peng-Fei Tang Jun Luo Ling-Yi Kong 
supports for this study were from the National Natural Science Foundation of China(31470416);the National New Drug Innovation Major Project(2018ZX09711-001-007);the National Key R&D Program of China(2018YFC1707105);the"Double First-Class"University project(CPU2018GY08,China).
Four new limonoids,toonayunnanaes F−I(1−4),and six known compounds(5−10)were isolated from the barks of Toona ciliata.Their structures were elucidated by thoroughly analyzing of NMR and HRMS data,and single-crystal X-...
关键词：MELIACEAE Toona ciliate LIMONOIDS NO inhibitory effects 
Highly oxygenous trichilin-type limonoids from Trichilia sinensis被引量：2
《Chinese Journal of Natural Medicines》2019年第12期912-917,共6页AN Fa-Liang YIN Yong LUO Jun KONG Ling-Yi 
supported by the National Natural Science Foundation of China(No.31470416);the Outstanding Youth Fund of the Basic Research Program of Jiangsu Province(No.BK20160077);the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT_15R63)
Six new trichilin-type limonoids(1-6)with C-19/29 lactol or acetal bridge and a new ring intact limonoid(7)were isolated from the desiccative ripe fruits of Trichilia sinensis.Their structures were determined by exten...
关键词：Trichilin-type limonoids Trichilia sinensis Cytotoxic activity 
Bioactive A-ring rearranged limonoids from the root barks of Walsura robusta
《Acta Pharmaceutica Sinica B》2019年第3期545-556,共12页Faliang An Xiaobing Wang Minghua Yang Jun Luo Lingyi Kong 
Financial support for this study by the National Natural Science Foundation of China (31470416, China);the Outstanding Youth Fund of the Basic Research Program of Jiangsu Province (BK20160077, China);the Program for Changjiang Scholars and Innovative Research Team in University (IRT_15R63, China);the "Double First-Class" University project (CPU2018GY08, China)
Screening active natural products, rapid identification, and accurate isolation are of great important for modern natural lead compounds discovery1. We hereby reported the isolation of seven new neotecleanin-type limo...
关键词：Walsura ROBUSTA LIMONOID Neotecleanin-type ECD spectrum calculation SINGLE-CRYSTAL X-ray diffraction Anti-inflammatory activity PROPIONIBACTERIUM acnes THP-1 human monocytic cell 
Two new nimbolinin-and trichilin-class limonoids isolated from the fruits of Melia azedarach
《Chinese Journal of Natural Medicines》2019年第3期227-230,共4页QIU Lu HENG Li XU Rong LUO Jun LI Yi 
supported by the National Natural Science Foundation of China(No.81573550);the Outstanding Youth Fund of the Basic Research Program of Jiangsu Province(BK20160077)
Two new furan fragment isomerized limonoids, meliazedalides A and B(compounds 1 and 2), were isolated from the fruits of Melia azedarach Linn.. Their chemical structures were elucidated on the basis of HR-ESI-MS and 1...
关键词：Melia azedarach MELIACEAE LIMONOID ANTI-INFLAMMATORY 
New limonoids isolated from the bark of Melia toosendan被引量：2
《Chinese Journal of Natural Medicines》2018年第12期946-950,共5页ZHANG Qiong ZHENG Qing-Hong SANG Yi-Shu SUNG Herman Ho-Yung MIN Zhi-Da 
supported by National Natural Science Foundation of China(No.31440027);Natural Science Foundation of Shanxi Province,China(No.201601D011123);Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi(No.2014133);Science and Technology Innovation Found of Shanxi Medical University(No.C01201008)
Two new limonoids, 12-ethoxynimbolinins G and H(compounds 1 and 2), and one known compound, toosendanin(Chuanliansu)(compound 3), were isolated from the bark of Melia toosendan. Their structures were elucidated by spe...
关键词：Melia toosendan MELIACEAE LIMONOID TOOSENDANIN ABSOLUTE configuration 
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