COACERVATE

作品数:17被引量:11H指数:3
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相关期刊:《Science China Chemistry》《BMEMat(BioMedical Engineering Materials)》《Chinese Journal of Polymer Science》《Accounts of Materials Research》更多>>
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An adhesive hydrogel for the treatment of oral ulcers
《Chinese Chemical Letters》2025年第3期385-388,共4页Xi Chen Xue Zhang Shuai Yang Jie Wang Tian Tang Maling Gou 
supported by the National Natural Science Foundation(No.32271468);Sichuan Science and Technology Program(No.2021JDTD0001);1·3·5 Project for disciplines of excellence,West China Hospital,Sichuan University(No.ZYYC23005);the Fundamental Research Funds for the Central Universities(No.2022SCU12046);Innovation Research Project of Sichuan University(No.2022SCUH0046).
Oral ulcers are a common ulcerative injury that occurs in the oral mucosa.When occurring,they can cause mucosal pain and affect eating and communication.The oral cavity,characterized by its moist environment and const...
关键词:Tea polyphenols Pluronic F68 Oral ulcers HYDROGEL COACERVATE 
Bioresponsive and transformable coacervate actuated by intestinal peristalsis for targeted treatment of intestinal bleeding and inflammation
《Bioactive Materials》2024年第11期627-639,共13页Yuqi Peng Xiaofen Luo Xinyu Wang c Enling Hu Ruiqi Xie Fei Lu Weiwei Ding Fangyin Dai Guangqian Lan 
Chongqing Postdoctoral International Exchange Training Program(7820100997);Fundamental Research Funds for Central Universities(Nos.SWU-XDPY22010);National College Students Innovation and Entrepreneurship Training Program(202310635114);National Natural Science Foundation of China(No.81703424);Chongqing Graduate Student Research Innovation Project(CYB21121).
Developing an oral in situ-forming hydrogel that targets the inflamed intestine to suppress bleeding ulcers and alleviate intestinal inflammation is crucial for effectively treating ulcerative colitis(UC).Here,inspire...
关键词:Intestinal ulcer bleeding Bioadhesive coacervate Intestinal peristalsis drive Bioresponsive transformation Adhesive hydrogel 
Lipocoacervate,a tunable vesicle for protein delivery
《Nano Research》2024年第10期9135-9140,共6页Chia-Wei Yeh Nathaniel Wright Chelsea Loh Nabeen Chu Yadong Wang 
Controlled delivery of proteins and other biologics is a growing medium of therapy for diseases previously untreatable.Here we report a self-assembling,tunable vesicle for the controlled delivery of growth factors and...
关键词:complex coacervate drug delivery protein delivery HEPARIN lipid particle 
Bioinspired coacervate-based bioinks for construction of multiscale tissue engineering scaffolds
《Nano Research》2024年第9期8209-8219,共11页Zhongwei Guo Shiqiang Zhang Yilin Guo Jingjing Xia Xiao Wu Hao Hu Rongcheng Hu Fangli Huang Qiulei Gao Chun Liu Jingjiang Qiu Wei Sun 
the projects of National Natural Science Foundation of China(No.32301209);Key R&D Projects of Henan Province(Nos.231111312400 and 241111220400).
Engineering hydrogels that resemble biological tissues of various lengths via conventional fabrication techniques remains challenging.Three-dimensional(3D)bioprinting has emerged as an advanced approach for constructi...
关键词:bioinks COACERVATION mineral-biopolymer NANOCLAY tissue engineering scaffold 
Polyelectrolyte Complexes and Coacervates Formed by De novo-Designed Peptides and Oligonucleotide
《Chinese Journal of Polymer Science》2024年第9期1333-1340,I0007,共9页Tian-Hao Ren De-Hai Liang 
supported by the National Natural Science Foundation of China(No.21973002).
The liquid-liquid phase separation of biopolymers in living cells contains multiple interactions and occurs in a dynamic environment.Resolving the regulation mechanism is still a challenge.In this work,we designed a s...
关键词:Polyelectrolyte complex COACERVATE PEPTIDES Secondary structure Electrostatic interaction 
Cation-Dipole Interaction-Induced Coacervate Underwater Adhesives in Natural Seawater
《Chinese Journal of Polymer Science》2024年第7期984-991,I0009,共9页Xu-Fei Liu Chong-Rui Zhang Hua-Wen Peng Qiang Zhao 
financially supported by the National Key R&D Program of China(No.2022YFB3805103);the National Natural Science Foundation of China(No.22178139)。
Significant progress has been made in wet adhesives for low salinity water,but exploration of general ionic adhesives for natural seawater is less developed because the high salinity could weaken interfacial bonding a...
关键词:COACERVATE Underwater adhesives Seawater Cation-dipole interaction 
Progress in constructing functional coacervate systems using microfluidics
《BMEMat(BioMedical Engineering Materials)》2024年第1期115-129,共15页Yuhao Geng Jing Yu 
Grant,Grant/Award Number:MOET2EP30220-0006;National Research Foundation Singapore,Grant/Award Number:NRF-NRFF11-2019-0004。
Coacervates formed by liquid-liquid phase separation play significant roles in a variety of intracellular and extracellular biological processes.Recently,substantial efforts have been invested in creating protocells u...
关键词:coacervate-core-vesicle(COV)systems liquid-liquid phase separation MICROFLUIDICS synthetic cells 
New insights into protein–polysaccharide complex coacervation:Dynamics,molecular parameters,and applications
《Aggregate》2024年第1期148-166,共19页Jiabao Zheng Paul Van der Meeren Weizheng Sun 
China Postdoctoral Science Foundation,Grant/Award Number:2023M731135;Ministry of Science and Technology of the People’s Republic of China,Grant/Award Number:DL2022163005L;National Natural Science Foundation of China,Grant/Award Number:32172257;Higher Education Discipline Innovation Project,Grant/Award Number:B17018;Postdoctoral Innovative Talent Support Program,Grant/Award Number:BX20230130。
For more than a decade,the discovery of liquid–liquid phase separation within living organisms has prompted colloid scientists to understand the connection between coacervate functionality,phase behavior,and dynamics...
关键词:DYNAMICS ENCAPSULATION liquid coacervate protein-polysaccharide complex coacervation solid precipitate 
Complex coacervate-derived hydrogel with asymmetric and reversible wet bioadhesion for preventing UV light-induced morbidities
《Bioactive Materials》2023年第12期62-72,共11页Xin Peng Yuan Li Menghui Liu Zhuo Li Xuemei Wang Kunyu Zhang Xin Zhao Gang Li Liming Bian 
the National Key Research and Development Program(2022YFB3804403);the Collaborative Research Fund from the Research Grants Council of Hong Kong(Project No.C5044-21G);the Research Grants Council of the Hong Kong Special Administration Region(project no.GRF/14202920,GRF/14204618,GRF/14108720,T13-402/17-N and AoE/M-402/20);National Natural Science Foundation of China(22205264).
Protecting the skin from UV light irradiation in wet and underwater environments is challenging due to the weak adhesion of existing sunscreen materials but highly desired.Herein we report a polyethyleneimine/thioctic...
关键词:Adhesive hydrogel COACERVATE Asymmetric adhesion Reversible adhesion 
The correlation between thermally induced precipitateto-coacervate transition and glass transition in a polyelectrolyte-bolaamphiphile complex
《Aggregate》2023年第5期189-198,共10页Xiaoqing Liu Zhihui Shi Feng Yu Chao Teng Chen Zhang Zhong-Ren Chen 
State Key Research Development Programme of China,Grant/Award Number:2021YFB3800702;National Natural Science Foundation of China,Grant/Award Number:21902073;Shenzhen Science and Technology Innovation Committee,Grant/Award Number:JSGG20210629144802007;Post-Doctoral Later-Stage Foundation Project of Shenzhen Polytechnic,Grant/Award Number:6021271003K。
The precipitate and the coacervate are two aggregated states in the polyelectrolyte complexes(PECs).The precipitate-to-coacervate transition and glass transition in PECs have been widely reported in the past.In many c...
关键词:aggregation-induced emission COACERVATE glass transition polyelectrolyte complex PRECIPITATE 
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