supported by the National Natural Science Foundation(No.32271468);Sichuan Science and Technology Program(No.2021JDTD0001);1·3·5 Project for disciplines of excellence,West China Hospital,Sichuan University(No.ZYYC23005);the Fundamental Research Funds for the Central Universities(No.2022SCU12046);Innovation Research Project of Sichuan University(No.2022SCUH0046).
Oral ulcers are a common ulcerative injury that occurs in the oral mucosa.When occurring,they can cause mucosal pain and affect eating and communication.The oral cavity,characterized by its moist environment and const...
Chongqing Postdoctoral International Exchange Training Program(7820100997);Fundamental Research Funds for Central Universities(Nos.SWU-XDPY22010);National College Students Innovation and Entrepreneurship Training Program(202310635114);National Natural Science Foundation of China(No.81703424);Chongqing Graduate Student Research Innovation Project(CYB21121).
Developing an oral in situ-forming hydrogel that targets the inflamed intestine to suppress bleeding ulcers and alleviate intestinal inflammation is crucial for effectively treating ulcerative colitis(UC).Here,inspire...
Controlled delivery of proteins and other biologics is a growing medium of therapy for diseases previously untreatable.Here we report a self-assembling,tunable vesicle for the controlled delivery of growth factors and...
the projects of National Natural Science Foundation of China(No.32301209);Key R&D Projects of Henan Province(Nos.231111312400 and 241111220400).
Engineering hydrogels that resemble biological tissues of various lengths via conventional fabrication techniques remains challenging.Three-dimensional(3D)bioprinting has emerged as an advanced approach for constructi...
supported by the National Natural Science Foundation of China(No.21973002).
The liquid-liquid phase separation of biopolymers in living cells contains multiple interactions and occurs in a dynamic environment.Resolving the regulation mechanism is still a challenge.In this work,we designed a s...
financially supported by the National Key R&D Program of China(No.2022YFB3805103);the National Natural Science Foundation of China(No.22178139)。
Significant progress has been made in wet adhesives for low salinity water,but exploration of general ionic adhesives for natural seawater is less developed because the high salinity could weaken interfacial bonding a...
Grant,Grant/Award Number:MOET2EP30220-0006;National Research Foundation Singapore,Grant/Award Number:NRF-NRFF11-2019-0004。
Coacervates formed by liquid-liquid phase separation play significant roles in a variety of intracellular and extracellular biological processes.Recently,substantial efforts have been invested in creating protocells u...
China Postdoctoral Science Foundation,Grant/Award Number:2023M731135;Ministry of Science and Technology of the People’s Republic of China,Grant/Award Number:DL2022163005L;National Natural Science Foundation of China,Grant/Award Number:32172257;Higher Education Discipline Innovation Project,Grant/Award Number:B17018;Postdoctoral Innovative Talent Support Program,Grant/Award Number:BX20230130。
For more than a decade,the discovery of liquid–liquid phase separation within living organisms has prompted colloid scientists to understand the connection between coacervate functionality,phase behavior,and dynamics...
the National Key Research and Development Program(2022YFB3804403);the Collaborative Research Fund from the Research Grants Council of Hong Kong(Project No.C5044-21G);the Research Grants Council of the Hong Kong Special Administration Region(project no.GRF/14202920,GRF/14204618,GRF/14108720,T13-402/17-N and AoE/M-402/20);National Natural Science Foundation of China(22205264).
Protecting the skin from UV light irradiation in wet and underwater environments is challenging due to the weak adhesion of existing sunscreen materials but highly desired.Herein we report a polyethyleneimine/thioctic...
State Key Research Development Programme of China,Grant/Award Number:2021YFB3800702;National Natural Science Foundation of China,Grant/Award Number:21902073;Shenzhen Science and Technology Innovation Committee,Grant/Award Number:JSGG20210629144802007;Post-Doctoral Later-Stage Foundation Project of Shenzhen Polytechnic,Grant/Award Number:6021271003K。
The precipitate and the coacervate are two aggregated states in the polyelectrolyte complexes(PECs).The precipitate-to-coacervate transition and glass transition in PECs have been widely reported in the past.In many c...