AROYL

作品数:27被引量:15H指数:2
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相关领域:理学医药卫生更多>>
相关作者:赵鹏张福义穆学军更多>>
相关机构:青海民族大学青海省药品检验检测院郑州大学苏州大学更多>>
相关期刊:《Chemical Research in Chinese Universities》《International Journal of Organic Chemistry》《Aggregate》《Chinese Journal of Chemistry》更多>>
相关基金:国家自然科学基金青海省科技计划项目广东省自然科学基金更多>>
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A Novel Synthesis Process of Cholesterol Ester by the Cross-Coupling of Cholesterol and Aroyl Chlorides
《International Journal of Organic Chemistry》2024年第4期123-127,共5页Mohammad Al-Masum Brooklyn Phillips 
Cholesterol is a sterol with a four-membered ring structure and a single hydroxyl group attached to one of the rings. It is the active, raw form of cholesterol. Cholesteryl Ester is the inactive form in which choleste...
关键词:CHOLESTEROL Cholesterol Esters CROSS-COUPLING MICROWAVE Aroyl Chloride 
Cooperative NHC/Photoredox Catalysis:Three-Component Reaction of Aroyl Fluorides,Styrenes and Oxalates
《Chinese Journal of Chemistry》2024年第5期511-515,共5页Zheng Lin Guanghui Lv Jianghong Liu Jiangyan Tang Binsong Mu Jian Chen Tianle Huang Zhongzhen Yang Yong Wu 
supported by Sichuan Science and Technology Program(No.2020YJ0221).
Cooperative NHC/photoredox catalysis has emerged as an important research field in recent years.Herein,this article describes the use of cesium salt derivatives of tert-alcohols as alkyl radical precursors in a three-...
关键词:Three-component PHOTOREDOX NHC Aryl ketones Iridium Radical C—C coupling AMIDES 
A redox-responsive self-assembling COA-4-arm PEG prodrug nanosystem for dual drug delivery suppresses cancer metastasis and drug resistance by downregulating hsp90 expression
《Acta Pharmaceutica Sinica B》2023年第7期3153-3167,共15页Yi Zhou Yingling Miao Qiudi Huang Wenwen Shi Jiacui Xie Jiachang Lin Pei Huang Chengfeng Yue Yuan Qin Xiyong Yu He Wang Linghao Qin Jianhai Chen 
supported by the National Natural Science Foundation of China(Nos.32101105;81373339);the 2021 Natural Science Foundation of Guangdong Province(Nos.2021A1515011367,China);the Southern Hospital Matching Fund(Nos.2013001,China);the High-Level university Academic Backbone and Training program in Guangzhou Medical University(Nos.B185004199,China);2022 City school joint funding project(Nos.202201020394,China);the 2018 Guangdong Key Discipline Construction Project of Pharmacy(Nos.Q185031010,China);the 2019 Undergraduate Laboratory Open Project(Nos.C195015003,China);Guangzhou Science and Technology Planning Project(Nos.202201010783,China)。
Metastasis and resistance are main causes to affect the outcome of the current anticancer therapies.Heat shock protein 90(Hsp90)as an ATP-dependent molecular chaperone takes important role in the tumor metastasis and ...
关键词:3-O-(Z)-Coumaroyloleanolic acid Cancer metastasis Drug resistance HSP90 Codelivery Prodrug nanosystem Chemotherapies Redox responsiveness 
基于网络药理学和分子对接探讨宁夏枸杞子中抑制免疫的成分及作用机制
《青海科技》2023年第2期88-99,共12页许地元 乔亚玲 才让南加 林鹏程 海平 
青海省科技计划项目(2020-SF-C32)。
通过网络药理学和分子对接技术,探究宁夏枸杞子乙酸乙酯萃取物中抑制程序性细胞死亡蛋白-1及其配体的活性成分及作用机制。通过检索文献和SwissTargetPrediction数据库,筛选出宁夏枸杞子乙酸乙酯萃取物中的成分及其对应靶点。在UniProt...
关键词:宁夏枸杞子 PD-1 PD-L1 N-E-coumaroyl tyramine 网络药理学 分子对接 
Further Developments on the Regioselective Synthesis of 3-Aroylindole Derivatives from C-Nitrosoaromatics and Alkynones: A Novel Synthetic Approach to Pravadoline, JWH-073, Indothiazinone Analogues and Related Compounds
《International Journal of Organic Chemistry》2022年第3期127-142,共16页Luca Scapinello Federico Vavassori Gabriella Ieronimo Keshav L. Ameta Giancarlo Cravotto Marco Simonetti Stefano Tollari Giovanni Palmisano Kenneth M. Nicholas Andrea Penoni Angelo Maspero 
An uncatalyzed and easily accessible synthetic approach for the preparation of 3-aroylindoles was investigated using nitrosoarenes and aromatic terminal ethynyl ketones. Indole derivatives were produced in good yields...
关键词:NITROSOARENES ALKYNONES INDOLES Cycoaddition ANNULATION 
Physicochemical and Analytical Studies of Some Monomer and Polymer Complexes Derived from Selected Aroyl Hydrazone
《Open Journal of Inorganic Chemistry》2022年第1期1-17,共17页Aymen Hussien Ahmed Mohsen Mahmoud Mostafa 
New solid complexes derived from the reaction of aroyl hydrazones, 2-hydroxy-1-naphthaldehyde benzene sulphonyl hydrazone (HNB), and 2-hydroxy-1-naphthaldehyde p-toluene sulphonyl hydrazone (HNT), with Co2+...
关键词:Aroyl Hydrazones Complexes Polymer and Monomer Complexes FTIR Synthesis Stoichiometry of Complexes 
Syntheses,Crystal Structures,Anticancer Activities and DNA-Binding Properties of the Dibutyltin Complexes Based on Benzoin Aroyl Hydrazone
《Chinese Journal of Structural Chemistry》2022年第2期105-113,I0010,共10页JIANG Wu-Jiu TAN Yu-Jun MAN Jia-Tai TAN Yu-Xing 
Supported by the Scientific Research Fund of Hunan Provincial Education Department of China(No.19C0279);Functional Metal-organic Compounds of Hunan Science and Technology Innovation Team。
Dibutyltin benzoin benzoyl hydrazone complex Ⅰ[C_(6)H_(5)(O)C=N-N=C(Ph)CH(Ph)O]_(2)[(n-Bu)_(2)Sn]_(2)and dibutyltin benzoin salicyl hydrazone complex Ⅱ[2-(OH)-C_(6)H_(4)(O)C=N-N=C(Ph)CH(Ph)O]_(2)[(n-Bu)_(2)Sn]_(2)we...
关键词:DIBUTYLTIN complex synthesis crystal structure DNA 
Solid-state emissive biphenylene bridged bisaroyl-S,N-ketene acetals as distinct aggregation-induced enhanced emitters and fluorometric probes
《Aggregate》2021年第5期179-184,共6页Lukas Biesen Thomas J.J.Muller 
Fonds der Chemischen Industrie;Deutsche Forschungsgemeinschaft,Grant/Award Number:Mu1088/9-1。
Biphenylene bridged bisaroyl-S,N-ketene acetals can be readily synthesized by a one-pot Masuda borylation-Suzuki arylation sequence,thus,yielding a library of 20 bisaroyl-S,N-ketene acetals with tunable solid-state em...
关键词:aggregation-induced emission aroyl-S N-ketene acetals liquor sensors one-pot reaction SOLID-STATE 
Copper-Catalyzed Modular Access to N-Fused Polycyclic Indoles and 5-Aroyl-pyrrol-2-ones via Intramolecular N-H/C-H Annulation with Alkynes:Scope and Mechanism Probes
《Chinese Journal of Chemistry》2020年第12期1545-1552,共8页Yan-Hua Liu Hong Song Chi Zhang Yue-Jin Liu Bing-Feng Shi 
Financial support from the NSFC(Nos.21925109,21772170);the Out-standing Young Talents of Zhejiang Province High-levelPersonnel of Special Support(No.ZJWR0108);the Fundamental Research Funds for the central UnIversitles(No.2018XZZX001-02)is gratefully acknowledged.
of main observation and concusion Copper-catalyzed intramolecular N-H/C-H annulation with alkynes has been developed.A vaniety ofdensely functionalized heterocycles,such as pyrrolo[1,2-a]indoles,indolo[1,2-c]quinazoli...
关键词:moiety Copper radical 
Study on the Biological Activity of 3-Aroyl-5-substituted Thiophene Derivatives Based on the CoMFA Method被引量:4
《Chinese Journal of Structural Chemistry》2020年第11期1978-1984,共7页FENG Hui FENG Chang-Jun CAO Jing-Pei 
supported by the National Natural Science Foundation of China (21676292,21075138);special fund of State Key Laboratory of Structure Chemistry (2016028)。
A three-dimensional quantitative structure-activity relationship(3 D-QSAR) study was conducted to analyze the A1 AR density(Bmax) of 56 3-aroyl-5-substituted thiophene derivatives(ASTDs) in human A1 Chinese hamster ov...
关键词:3-aroyl-5-substituted thiophene derivatives(ASTDs) A1AR density(Bmax) three-dimensional quantitative structure-activity relationship comparative molecular field analysis 
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