NORADRENERGIC

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Microstructural integrity of the locus coeruleus and its tracts reflect noradrenergic degeneration in Alzheimer’s disease and Parkinson’s disease
《Translational Neurodegeneration》2024年第1期963-979,共17页Chen-Pei Lin Irene Frigerio John G.J.M.Bol Maud M.A.Bouwman Alex J.Wesseling Martin J.Dahl Annemieke J.M.Rozemuller Ysbrand D.van der Werf Petra J.W.Pouwels Wilma D.J.van de Berg Laura E.Jonkman 
funded by The Michael J.Fox Foundation(17253).
Background Degeneration of the locus coeruleus(LC)noradrenergic system contributes to clinical symptoms in Alzheimer’s disease(AD)and Parkinson’s disease(PD).Diffusion magnetic resonance imaging(MRI)has the potentia...
关键词：Locus coeruleus Noradrenergic degeneration Alzheimer’s disease Parkinson’s disease Diffusion MRI POST-MORTEM HISTOPATHOLOGY 
Noradrenergic, glutamatergic and dopaminergic systems are implicated in antidepressant-like effect of flavonoids extracted from okra (Abelmoschus esculentus [L.] Moench.) fruit in the forced swimming test
《Journal of Polyphenols》2022年第1期17-31,共15页Fuyuan Li Xiaozhuo Zhang Qianqian Mao Bo Wu Ying Jia Tingxu Yan 
This research was supported by Shenyang Scientific Project(No.F13-287-1-00);Liaoning Province Natural Science Foundation(No.2014020076).
Okra(Abelmoschus esculentus[L.]Moench.)is one of the most frequently used herbals in East or West Africa,and its various biological activities have been widely studied.Flavonoids extracted from many plants are reporte...
关键词：OKRA ANTIDEPRESSANT forced swimming test(FST) mechanism flavonoid compound 
Multi-targets antidepressant mechanism of the bis-benzylisoquinoline 7-O-ethylfangchinoline:Involvement of noradrenergic,dopaminergic and AMPAergic systems
《中国药理学与毒理学杂志》2015年第S1期44-44,共1页Zhao-fuSHENG Xiang-yuCUI Su-yingCUI BinYU Xue-qiongZHANG Sheng-jieLI QingCAO Yuan-liHUANG Ya-pingXU Jin-zhiSONG HuiDING Zhi-geLIN GuangYANG Yong-heZHANG 
The project supported by National Natural Science Foundation of China(81173031,81202511 and81302746)
OBJECTIVE Bisbenzylisoquinoline(BBI)alkaloids have extensive pharmacological functions.The aim of this study was to investigate the mechanisms underlying the antidepressant-like action of 7-O-ethylfangchinoline(YH-200...
关键词：depression YH-200 multi-targets FORCED SWIMMING te 
The Ventral Ascending Noradrenergic Bundles Are Involved in the Stress Response to Immobilization in Rats
《Journal of Behavioral and Brain Science》2015年第3期88-95,共8页Toshihiro Yoshihara Yasutaka Yawaka 
Stressful stimuli induced by immobilization are perceived as acute stress in rats. This acute stress activates corticotropin-releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus (PVN), resulting...
关键词：Hypothalamus-Pituitary-Adrenal Axis IMMOBILIZATION Stress 6-HYDROXYDOPAMINE VENTRAL Ascending BUNDLES of NORADRENERGIC Neurons Rat 
Noradrenergic mechanism in the regulation of seizures in GEPR.
《中国药理通讯》2004年第2期3-4,共2页Kwang-HoKo Dong-OokSeo Jae-RyunRyu Chan-YoungShin 
Genetically epilepsy prone rat (GEPR) is a model of generalized tonic/clonic epilepsy and a useful tool in the understanding of basic mechanisms of human epilepsy. GEPR is susceptible to audiogenic seizure, hypertherm...
关键词：去甲肾上腺素 遗传性癫痫 大鼠 动物模型 
Modulation of neuronal activity of cerebellar fastigial nucleus by locus coeruleus stimulation in the rat
《Chinese Science Bulletin》1998年第11期940-944,共5页Wang Tao Wang Jianjun Cheng Hong Li Hongzhao Yu Qixiang 
ThisworkwassupportedbytheNationalNaturalScienceFoundationofChina (GrantNos.395 70 2 46,39770 2 49) ,NaturalScienceFoundationofJiangsuProvince (GrantNo .BK970 45 )andagrantinaidofscholarsreturningfromo verseasfromtheStateEducationCommissionofChina (G
The effects of stimulating locus coeruleus (LC) on neuronal activity of cerebellar fastigial nucleus (FN) was investigated. Stimulation of LC elicited inhibitory, excitatory and biphasic (inhibition-excitation) respon...
关键词：LOCUS coeruleus CEREBELLAR fastigial NUCLEUS coeruleo-cerebellar PATHWAY NORADRENERGIC fibers. 
CHANGES IN FIRING RATE OF NORADRENERGIC NEURONS IN LOCUS COERULEUS FOLLOWING STIMULATION OF MEDIAL PREOPTIC AREA IN FEMALE RATS AT DIFFERENT STAGES OF THE ESTROUS CYCLE
《Chinese Science Bulletin》1991年第4期333-338,共6页朱笛霓 孙启新 赵建础 
Several studies showed that sex hormone receptors are in close relationship with classical neurotransmitter neurons especially catecholaminergic(CA) neurons. There are many gonadotrophin releasing hormone (GnRH) neuro...
关键词：MEDIAL PREOPTIC area NORADRENERGIC neuron LOCUS coeruleus ESTRUS DIESTRUS rat. 
THE ROLE OF LOCUS COERULEUS-NORADRENERGIC AND DORSAL RAPHE NUCLEUS-SEROTONERGIC SYSTEMS IN ANALGESIC EFFECT OF HYPOTHA-LAMIC ARCUATE NUCLEUS STIMULATION
《Chinese Science Bulletin》1987年第11期773-777,共5页张卫和 龚珊 殷伟平 印其章 
Project supported by the Science Fund of Academia Sinica (82, No. 100).
Previous studies ia our laboratory have shown that hypothalamic arcuate nucleus (ARC),locus coeruleus (LG) and dorsal raphe nucleus (DR) play an important role in pain modulation and acupuncture analgesia, There is su...
关键词：neuronal analgesia HYPOTHALAMIC acupuncture STIMULATION nucleus RAPHE locus VENTRICLE DORSAL 
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