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Neuronal guidance factor Sema3A inhibits neurite ingrowth and prevents chondrocyte hypertrophy in the degeneration of knee cartilage in mice,monkeys and humans: 《Bone Research》2025年第1期75-90,共16页Shishu Huang Dashuang Gao Zhenxia Li Hongchen He Xi Yu Xuanhe You Diwei Wu Ze Du Jiancheng Zeng Xiaojun Shi Qinshen Hu Yong Nie Zhong Zhang Zeyu Luo Duan Wang Zhihe Zhao Lingli Li Guanglin Wang Liping Wang Zongke Zhou Di Chen Fan Yang; partly National Key R&D Program of China(2023YFA1801200,2023YFA1801202);Major Program of the National Natural Science Foundation of China(T2394532);National Natural Science Foundation of China(82072489);The Foundation of Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions(NYKFKT2019007);Shenzhen Medical Research Fund(B2302011);The Sanming Project of Medicine in Shenzhen(SZZYSM202311013);The China Postdoctoral Science Foundational,2023M743679;Shenzhen Science and Technology Research Funding(JCYJ20220818101414032);Key Research Project of Science&Technology Department of Sichuan Province,China(2024YFFK0041)。; Osteoarthritis(OA)is a degenerative joint disease accompanied with the loss of cartilage and consequent nociceptive symptoms.Normal articular cartilage maintains at aneural state.Neuron guidance factor Semaphorin 3A(S...; 关键词：SEMA3A CARTILAGE HYPERTROPHY

Porous tantalum structure integrated on Ti6Al4V base by Laser Powder Bed Fusion for enhanced bony-ingrowth implants:In vitro and in vivo validation被引量：5: 《Bioactive Materials》2022年第1期3-13,共11页Pengfei Lei Hu Qian Taomei Zhang Ting Lei Yihe Hu Chao Chen Kechao Zhou; This study was supported by the Natural Science Foundation of Hunan Province,China(Grant No.2019JJ40499);the Scientific Research Project of Health and Family Planning Commission of Hunan Province,China(Grant No.B2019188);the Science and technology Innovation Leading Project for High-tech Industry of Hunan Province(Grant No.2020SK2008);the Major science and technology projects of Changsha City(Grant No.42193);National key research and development project(2018YFB1105504);Natural Science Foundation of China(Grant No.82002277 and 81672656).; Despite the widespread application of Ti6Al4V and tantalum(Ta)in orthopedics,bioinertia and high cost limit their further applicability,respectively,and tremendous efforts have been made on the Ti6Al4V-Ta alloy and Ta...; 关键词：Tantalum TI6AL4V Laser powder bed fusion Orthopedic scaffolds OSTEOINTEGRATION

Long-term variability of root production in bioenergy crops from ingrowth core measurements被引量：1: 《Journal of Plant Ecology》2021年第5期757-770,共14页Cheyenne Lei Michael Abraha Jiquan Chen Yahn-Jauh Su; Support for this research was provided by the Great Lakes Bioenergy Research Center,U.S.Department of Energy,Office of Science,Office of Biological and Environmental Research(Awards DE-SC0018409 and DE-FCO2-07ER64494);by the National Science Foundation Long-term Ecological Research Program(DEB 1832042)at the Kellogg Biological Station,and by Michigan State University AgBioResearch.; Aims Long-term determination of root biomass production upon land-use conversion to biofuel crops is rare.To assess land-use legacy influences on belowground biomass accumulation,we converted 22-year-old Conservation ...; 关键词：biofuel ecosystems corn ingrowth core method root biomass restored prairie SWITCHGRASS

A biomimetic basementmembrane consisted of hybrid aligned nanofibers andmicrofibers with immobilized collagen IV and laminin for rapid endothelialization被引量：1: 《Bio-Design and Manufacturing》2021年第2期171-189,共19页Chenglong Yu Guoping Guan Stefanie Glas Lu Wang Zhutong Li Lih-Sheng Turng; This work was supported by the Fundamental Research Funds for the Central Universities(Nos.2232019G-06 and 2232019A3-06);111 project(No.PB0719035);The authors at University of Wisconsin-Madison would like to acknowledge the partial support by the Wisconsin Institute for Discovery(WID),the NHLBI of the National Institutes of Health(No.U01HL134655);the Kuo K.and Cindy F.Wang Professorship.Chenglong Yu also acknowledged the fellowship from the China Scholarship Council(CSC)under the Grant CSC No.201906630070.; Rapid formation of a continuous endothelial cell(EC)monolayer with healthy endothelium function on the luminal surface of vascular implants is imperative to improve the longtime patency of small-diameter vascular impl...; 关键词：Biomimetic basement membranes Aligned electrospun fibers Surface modification ENDOTHELIALIZATION Anti-thrombogenicity Transmural ingrowth

Effects of pore size and porosity of surface-modified porous titanium implants on bone tissue ingrowth被引量：12: 《Transactions of Nonferrous Metals Society of China》2019年第12期2534-2545,共12页Jing-pu ZHENG Liang-jian CHEN Dai-yuan CHEN Chun-sheng SHAO Man-fei YI Bo ZHANG; Project(81571021) supported by the National Natural Science Foundation of China;Projects(2015WK3012,2018SK2017) supported by the Hunan Provincial Science and Technology Department Project,China;Project(20160301) supported by New Talent Project of the Third Xiangya Hospital of Central South University,China; The effects of surface-modified porous titanium implants with different porosities and pore sizes on osseointegration were investigated in vivo.Three porous titanium implants(A30,A40 and A50 containing volume fraction...; 关键词：porous titanium implant POROSITY aperture INTERCONNECTIVITY OSSEOINTEGRATION