REMODELLING

作品数：30被引量：96H指数：5
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相关领域：医药卫生更多>>
相关作者：王瑶金佳敏蔡协艺张薇杨驰更多>>
相关机构：首都医科大学附属北京口腔医院第三军医大学西南医院上海交通大学医学院附属第九人民医院山东大学更多>>
相关期刊：《Life Metabolism》《Journal of Pharmaceutical Analysis》《Protection and Control of Modern Power Systems》《Acta Biochimica et Biophysica Sinica》更多>>
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Vascular fibrosis and extracellular matrix remodelling in post-COVID 19 conditions
《Infectious Medicine》2024年第4期93-102,共10页Anna Kamdar Robert Sykes Cameron R.Thomson Kenneth Mangion Daniel Ang Michelle AW Lee Tom Van Agtmael Colin Berry 
Ms Anna Kamdar is supported by research funding from the British Heart Foundation MBPhD(FS/MBPhD/22/28011);Robert Sykes is supported by funding from the British Heart Foundation Centre of Research Excellence award(RE/18/6/34217);NHS Greater Glasgow and Clyde Endowment Fund-ing(GN21CA394);Cameron Thomson is supported by research funding from The University of Glasgow Doctoral Training Programme.Dr Kenneth Mangion is supported by research funding from the Chief Scientist Office(COV/LTE/20/10,COV/GLA/20/05);Ms Michelle Lee is supported by research funding from the British Heart Foundation Centre of Research Excel-lence(RE/18/6/34217);Professor Tom Van Agtmael is supported by research funding from EPSRC-Horizon Europe(EP/X031721/1[EU Ref:101072766])and MRC(MR/R005567/1);Professor Colin Berry is supported by research funding from the British Heart Foundation(FS/17/26/32744,PG/18/52-33892,RE/18/6/34217)and Medical Research Council(MR/SO18905/1).
Causal associations between viral infections and acute myocardial injury are not fully understood,with mech-anisms potentially involving direct cardiovascular involvement or systemic inflammation.This review explores ...
关键词：COVID-19 Post-COVID-19 syndrome Matrix remodelling Vascular dysfunction MYOCARDITIS 
Terpene extract from the stem of Celastrus orbiculatus inhibits actin cytoskeleton remodelling in gastric cancer cells by regulating the protein interaction between PTBP1 and ACTN4
《Journal of Pharmaceutical Analysis》2024年第8期1158-1175,共18页Zewen Chu Miao Zhu Yuanyuan Luo Yaqi Hu Xinyi Feng Jiacheng Shen Haibo Wang Masataka Sunagawa Yanqing Liu 
financially supported by the National Natural Science Foundation of China(Grant Nos.:82274603 and 82104946);the Natural Science Foundation of Jiangsu Province,China(Grant No.:BK20210817);the Traditional Chinese Medicine Science and Technology Development Project of Jiangsu Province,China(Project code:QN202008);the Young Scientific and Technological Talents Uplift Project of Jiangsu Association of Integrated Traditional Chinese and Western Medicine,China(Grant No.:JSZXTJ-2024-A05);the Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(Grant No.:KYCX21_3295);the Yangzhou University Graduate Student International Academic Exchange Special Fund Project,China.Thanks for the Graphical abstract drawn。
Adjuvant chemoradiotherapy,molecular targeted therapy,and immunotherapy are frequently employed to extend the survival of patients with advanced gastric cancer(GC).However,most of these treatments have toxic side effe...
关键词：Traditional Chinese medicine Polypyrimidine tract binding protein 1 Alpha actinin-4 Gastric cancer Actin skeleton remodelling 
Investigating the relationship between intracranial atherosclerotic plaque remodelling and diabetes using high-resolution vessel wall imaging被引量：1
《World Journal of Diabetes》2024年第1期72-80,共9页Yong-Qian Mo Hai-Yu Luo Han-Wen Zhang Yu-Feng Liu Kan Deng Xiao-Lei Liu Biao Huang Fan Lin 
Supported by National Natural Science Foundation of China,No.82071871;Guangdong Basic and Applied Basic Research Foundation,No.2021A1515220131;Guangdong Medical Science and Technology Research Fund Project,No.2022111520491834;Clinical Research Project of Shenzhen Second People's Hospital,No.20223357022。
BACKGROUND Intracranial atherosclerosis,a leading cause of stroke,involves arterial plaque formation.This study explores the link between plaque remodelling patterns and diabetes using high-resolution vessel wall imag...
关键词：High-resolution vessel wall imaging Intracranial atherosclerosis Vascular remodelling Magnetic resonance imaging 
Extracellular matrix remodelling in dental pulp tissue of carious human teeth through the prism of single-cell RNA sequencing被引量：3
《International Journal of Oral Science》2023年第3期450-461,共12页Anamaria Balic Dilara Perver Pierfrancesco Pagella Hubert Rehrauer Bernd Stadlinger Andreas E.Moor Viola Vogel Thimios A.Mitsiadis 
Carious lesions are bacteria-caused destructions of the mineralised dental tissues,marked by the simultaneous activation of immune responses and regenerative events within the soft dental pulp tissue.While major molec...
关键词：ORGANS PULP matrix 
Extracellular matrix remodelling in obesity and metabolic disorders被引量：2
《Life Metabolism》2023年第4期7-21,共15页Vishal Musale David H.Wasserman Li Kang 
supported by Diabetes UK(15/0005256 and 21/0006329 to L.K.);British Heart Foundation(PG/18/56/33935 to L.K.);European Commission Marie Curie International Incoming Fellowship 625119(to L.K.);National Institute of Diabetes and Digestive and Kidney Diseases(NIDDK)(DK059637,DK054902,and DK050277 to D.W.).
Obesity causes extracellular matrix (ECM) remodelling which can develop into serious pathology and fibrosis, having metabolic effects in insulin-sensitive tissues. The ECM components may be increased in response to ov...
关键词：extracellular matrix FIBROSIS insulin resistance OBESITY METABOLISM 
Protein kinase inhibitors affect spermatogenic functions and blood testis barrier remodelling:A scoping review被引量：1
《Asian pacific Journal of Reproduction》2023年第3期97-108,共12页Oyovwi Mega Obukohwo Onome Bright Oghenetega Falajiki Yewande Faith Emojevwe Victor Rotu Arientare Rume Joseph Gregory Uchechukwu Oyeleke Abiodun Abioye 
Objective:To identify the role of protein kinase in male reproduction in animal models and human spermatogenic function.Methods:This study assessed the protein kinase of male reproduction in animal models and human us...
关键词：SPERMATOGENESIS Protein kinase INHIBITORS Sertoli cells CAPACITATION MTOR 
Reliability and efficiency enhancement of a radial distribution system through value-based auto-recloser placement and network remodelling被引量：5
《Protection and Control of Modern Power Systems》2023年第1期1-14,共14页Bratati Ghosh Ajoy Kumar Chakraborty Arup Ratan Bhowmik 
The electric distribution system(EDS)is prone to faults leading to power interruptions.The present energy market demands that electricity utilities invest more in different measures to improve the performance of the E...
关键词：Auto-recloser placement Load flow Metaheuristic optimization algorithm Power loss minimization Reconfiguration Reliability assessment 
circ-BPTF serves as a miR-486-5p sponge to regulate CEMIP and promotes hypoxic pulmonary arterial smooth muscle cell proliferation in COPD被引量：2
《Acta Biochimica et Biophysica Sinica》2023年第3期438-448,共11页Changguo Wang Yingying Liu Weiyun Zhang Jian’an Huang Junhong Jiang Ran Wang Daxiong Zeng 
supported by the grants from the Suzhou Municipal Application Basic Research Project(SYS2019047);the Program of Key Talents of Medical Science in Jiangsu Province(QNRC2016745);the National Nature Science Foundation of China(No.81970051).
Hypoxia plays a crucial role in pulmonary vascular remodelling at the early stage of chronic obstructive pulmonary disease(COPD).Circle RNA(circRNA)has been identified to play a critical role in multiple diseases.Howe...
关键词：pulmonary vascular remodelling hypoxia chronic obstructive pulmonary disease(COPD) circ-BPTF miR-486-5p CEMIP 
Integrated printed BDNF-stimulated HUCMSCs-derived exosomes/collagen/chitosan biological scaffolds with 3D printing technology promoted the remodelling of neural networks after traumatic brain injury被引量：5
《Regenerative Biomaterials》2023年第1期40-52,共13页Xiaoyin Liu Jian Zhang Xu Cheng Peng Liu Qingbo Feng Shan Wang Yuanyou Li Haoran Gu Lin Zhong Miao Chen Liangxue Zhou 
supported by the National Major Scientific and Technological Special Project for Significant New Drugs Development(2015ZX09102010).
The restoration of nerve dysfunction after traumatic brain injury(TBI)faces huge challenges due to the limited self-regenerative abilities of nerve tissues.In situ inductive recovery can be achieved utilizing biologic...
关键词：collagen CHITOSAN BDNF exosomes mesenchymal stem cell traumatic brain injury 
HIV-induced membraneless organelles orchestrate post-nuclear entry steps被引量：1
《Journal of Molecular Cell Biology》2022年第11期9-23,共15页Viviana Scoca Renaud Morin Maxence Collard Jean-Yves Tinevez Francesca Di Nunzio 
funded by the ANRS REACTing grant(ECTZ88162)with a nominative PhD student fellowship(ECTZ88177)for V.S.;the Sidaction/Fondation pour la Recherche Médicale(FRM)grant(VIH20170718001);Institut Pasteur.
HIV integration occurs in chromatin sites that favor the release of high levels of viral progeny;alternatively, the virus is alsoable to discreetly coexist with the host. The viral infection perturbs the cellular envi...
关键词：HIV nuclear condensates nuclear remodelling phase separation reverse transcription 
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