ERYTHROID

作品数：116被引量：324H指数：10
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相关领域：医药卫生生物学更多>>
相关作者：齐亚德杨晨辉周德权王磊王中更多>>
相关机构：华中科技大学河北医科大学中国医学科学院北京协和医学院北京协和医院更多>>
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相关基金：国家自然科学基金北京市自然科学基金福建省自然科学基金国家教育部博士点基金更多>>
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Hypidone hydrochloride(YL-0919)ameliorates functional deficits after traumatic brain injury in mice by activating the sigma-1 receptor for antioxidation被引量：1
《Neural Regeneration Research》2025年第8期2325-2336,共12页Yafan Bai Hui Ma Yue Zhang Jinfeng Li Xiaojuan Hou Yixin Yang Guyan Wang Yunfeng Li 
supported by the National Natural Science Foundation of China,Nos.82204360(to HM)and 82270411(to GW);National Science and Technology Innovation 2030 Major Program,No.2021ZD0200900(to YL)。
Traumatic brain injury involves complex pathophysiological mechanisms,among which oxidative stress significantly contributes to the occurrence of secondary injury.In this study,we evaluated hypidone hydrochloride(YL-0...
关键词：antidepressant drug blood-brain barrier cognitive function hypidone hydrochloride(YL-0919) neurological function nuclear factor-erythroid 2 related factor 2 oxidative stress sigma-1 receptor superoxide dismutase traumatic brain injury 
Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2
《Neural Regeneration Research》2025年第6期1776-1788,共13页Zige Jiang Dexiang Liu Tingting Li Chengcheng Gai Danqing Xin Yijing Zhao Yan Song Yahong Cheng Tong Li Zhen Wang 
supported by the National Natural Science Foundation of China,Nos.82271327 (to ZW),82072535 (to ZW),81873768 (to ZW),and 82001253 (to TL)。
The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and ce...
关键词：apoptosis CYSTATHIONINE-Β-SYNTHASE nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide MITOCHONDRION NEUROPLASTICITY oxidative stress quinolinic acid reactive oxygen species 
Double-edged sword of L-arginine in diabetes:Exploring antiinflammatory and antioxidant strategies
《World Journal of Diabetes》2025年第4期314-317,共4页Shuai Liu Ning Li Jia-Jia Jin Yong-Wei Yu 
The article by Mansouri et al provides a comprehensive investigation into the effects of L-arginine(L-Arg)on diabetic cardiomyopathy.The authors conclude that while a low dose(0.5 g/kg)of L-Arg improves lipid profiles...
关键词：L-ARGININE Diabetic cardiomyopathy Oxidative stress Nuclear factor erythroid 2-related factor 2 Nitric oxide synthase 
The role of nuclear factor erythroid 2-related factor 2(NRF2)in arsenic toxicity
《Journal of Environmental Sciences》2025年第4期632-644,共13页Sara R.El-Mahrouk Mahmoud A.El-Ghiaty Ayman O.S.El-Kadi 
supported by the Natural Sciences and Engineering Research Council of Canada(NSERC)Discovery Grant[RGPIN 250139]to A.O.S.E.
Arsenic,a naturally occurring toxic element,manifests in various chemical forms and is widespread in the environment.Exposure to arsenic is a well-established risk factor for an elevated incidence of various cancers a...
关键词：ARSENIC NRF2 KEAP1 NQO1 HMOX1 Oxidative stress 
Gentiopicroside Alleviates Atherosclerosis by Suppressing Reactive Oxygen Species-Dependent NLRP3 Inflammasome Activation in Vascular Endothelial Cells via SIRT1/Nrf2 Pathway
《Chinese Journal of Integrative Medicine》2025年第2期118-130,共13页LI Zhu-qing ZHANG Feng LI Qi WANG Li SUN Xiao-qiang LI Chao YIN Xue-mei LIU Chun-lei WANG Yan-xin DU Xiao-yu LU Cheng-zhi 
Supported by the National Natural Science Foundation of China(No.82300445);the Natural Science Foundation of Tianjin(No.22JCQNJC01130);the Medical Health Science and Technology Project of Tianjin Municipal Health Commission(No.TJWJ2023QN026)。
Objective:To evaluate the protective effects of gentiopicroside(GPS)against reactive oxygen species(ROS)-induced NOD-like receptor family,pyrin domain containing 3(NLRP3)inflammasome activation in endothelial cells,ai...
关键词：endothelial dysfunction GENTIOPICROSIDE NLRP3 inflammasome SIRT1 nuclear factor erythroid 2-related factor 2 Chinese medicine 
MiR-340-5p affects the proliferation and transfer of gastric cancer cells by targeting lncRNA HCG11 and NRF2 expression
《Oncology and Translational Medicine》2025年第1期29-35,共7页Rina Su Wei Luan Kai Zhang Shuai Liu Xiaoqing Zhang Yanwei Gao 
Funded by the general program of the Nature Fund of InnerMongolia Autonomous Region.
Objective:The aim of the study was to investigate the expression and biological role of nuclear factor erythroid–related factor 2(NRF2)in gastric cancer cells.Methods:Western blotting(WB)and reverse transcription-pol...
关键词：Gastric cancer Nuclear factor erythroid 2 related factor 2(NRF2) Apoptosis COX-2/PEG 2 signaling pathway 
Zhongfeng Xingnao Liquid ameliorates post-stroke cognitive impairment through sirtuin1(SIRT1)/nuclear factor erythroid 2-related factor 2(Nrf2)/heme oxygenase 1(HO-1)pathway
《Chinese Journal of Natural Medicines》2025年第1期77-89,共13页Wenqin Yang Wen Wen Hao Chen Haijun Zhang Yun Lu Ping Wang Shijun Xu 
supported by the Science&Technology Department of Sichuan Province(No.2019YFS0040);the Improvement Plan of“Xinglin Scholar”Scientific Research Talent,Chengdu University of Traditional Chinese Medicine(No.XKTD2022002)。
The activation of the sirtuin1(SIRT1)/nuclear factor erythroid 2-related factor 2(Nrf2)/heme oxygenase 1(HO-1)pathway has been shown to mitigate oxidative stress-induced apoptosis and mitochondrial damage by reducing ...
关键词：Zhongfeng Xingnao Liquid Post-stroke cognitive impairment Oxidative stress Mitochondrial function Apoptosis Sirtuin1/nuclear factor erythroid 2-related factor 2/heme oxygenase 1 pathway 
Adult megakaryopoiesis:when taking a short-cut results in a different final destination
《Blood Science》2024年第4期60-61,共2页Wenxu Zhu Gavin Tjin Louise E.Purton 
It is now well-established that there are 2 distinct pathways for megakaryopoiesis.One is defined by the traditional stepwise differentiation pathway that progresses from hematopoietic stem and progenitor cells(HSPCs)...
关键词：STEPWISE ERYTHROID sis 
Clinical characteristics and prognosis of patients with myelodysplastic syndrome with a bone marrow nucleated erythroid cell proportion of greater than or equal to 50%
《China Medical Abstracts(Internal Medicine)》2024年第4期228-229,共2页ZENG Yanping 
Objective To analyze the clinical characteristics and prognosis of patients with myelodysplastic syndrome(MDS)with a bone marrow nucleated erythroid cell proportion of greater than or equal to 50%(MDS-E).Methods The c...
关键词：PATIENTS Blood PROGNOSIS 
Vanillylacetone attenuates cadmium chloride-induced hippocampal damage and memory loss through upregulation of nuclear factor erythroid 2-related factor 2 gene and protein expression
《Neural Regeneration Research》2024年第12期2750-2759,共10页Fahaid H.A.L-Hashem Salah O.Bashir Amal F.Dawood Moutasem S.Aboonq Ismaeel Bin-Jaliah Abdulaiziz M.Al-Garni Mohamed D.Morsy 
funded by the Research Deanship of King Khalid University,No.GRP-215-43 (to FHA);Princess Nourah bint Abdulrohman University Researchers Supporting Project,No.PNURSP2023R110 (to AFD)。
Memory loss and dementia are major public health concerns with a substantial economic burden.Oxidative stress has been shown to play a crucial role in the pathophysiology of hippocampal damage-induced memory impairmen...
关键词：HIPPOCAMPUS NEUROPROTECTIVE Nrf2 gene oxidative stress vanillylacetone 
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