L-LACTATE

作品数：4被引量：7H指数：2
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相关领域：医药卫生理学更多>>
相关作者：吴艳华曹洪玉郑学仿蒋革更多>>
相关机构：大连大学大连医科大学更多>>
相关期刊：《Neuroscience Bulletin》《Synthetic and Systems Biotechnology》《Neural Regeneration Research》《华南师范大学学报（自然科学版）》更多>>
相关基金：国家自然科学基金辽宁省自然科学基金更多>>
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Does astrocytic L-lactate enhance cognition through myelination?
《Neural Regeneration Research》2024年第6期1167-1168,共2页Mastura Akter Ying Li 
funded by the General Research Fund(GRF)of the Research Grants Council of Hong Kong,China(11103721,11102820,and 11100018);the National Natural Science Foundation of China(NSFC)and RGC Joint Research Scheme(3171101014,N_CityU114/17);the Innovation and Technology Fund Hong Kong,China(CityU 9445909)(all to YL);supported by a grant from City University of Hong Kong Neuroscience Research Infrastructure(9610211);a grant from Center for Biosystems;Neuroscience,and Nanotechnology(9360148)(both to YL)。
Introduction:Astrocytes,the predominant glial cell in the brain,play a vital role in a plethora of central nervous system functions.They are the major storage site of glycogen in the central nervous system.They produc...
关键词：MYELIN specialized predominant 
Elevated L-lactate Promotes Major Cellular Pathologies Associated with Neurodegenerative Diseases
《Neuroscience Bulletin》2021年第3期380-384,共5页Andrew DChapp Jessica EBehnke Kyle MDriscoll Taija Hahka Zoe LaLonde Zhiying Shan Qing-Hui Chen 
Dear Editor,Small,short-chain fatty acids(SCFAs)(acetic acid,propionic acid,and butyric acid:conjugate bases,acetate,propionate,and butyrate)as well as the alpha-hydroxy acid,L-lactic acid(conjugate base,L-lactate)are...
关键词：CONJUGATE BASES QUANTITIES 
Conversion of D-glucose to L-lactate via pyruvate by an optimized cell-free enzymatic biosystem containing minimized reactions被引量：2
《Synthetic and Systems Biotechnology》2018年第3期204-210,共7页Leipeng Xie Xinlei Wei Xigui Zhou Dongdong Meng Ruimin Zhou Yi-Heng P.Job Zhang Shuxia Xu Chun You 
the Key Research Program of the Chinese Academy of Sciences(Grant No.ZDRW-ZS-2016-3);National Natural Science Foundation of China(Grant No.31600636).
Cell-free synthetic enzymatic biosystem is emerging to expand the traditional biotechnological mode by utilizing a number of purified/partially purified enzymes and coenzymes in a single reaction vessel for the produc...
关键词：Cell-free synthetic enzymatic biosystem Minimized reactions Thermophilic enzymes L-LACTATE PYRUVATE Biomanufacturing 
虚拟筛选竞争性抑制NDRG3与L-Lactate结合的小分子研究被引量：5
《华南师范大学学报（自然科学版）》2018年第3期58-64,共7页曹洪玉 吴艳华 周兴智 郑学仿 蒋革 
国家自然科学基金项目(21601025);大连市青年科技之星项目(2017RQ156);辽宁省自然科学基金指导计划项目(201602020)
竞争性抑制NDRG3(N-myc Downstream Regulated Gene 3)蛋白与L-Lactate结合可有效阻遏NDRG3介导的低氧反应.文中通过同源模建技术构建NDRG3蛋白的三维结构,并将L-Lactate对接到NDRG3蛋白的潜在活性位点中,发现L-Lactate主要通过与Asn133...
关键词：NDRG3 L-LACTATE 竞争性抑制剂 同源模建 分子对接 虚拟筛选 
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