EICOSANOID

作品数:8被引量:22H指数:3
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相关领域:医药卫生更多>>
相关期刊:《Journal of Animal Science and Biotechnology》《World Journal of Gastroenterology》《Genomics, Proteomics & Bioinformatics》《Insect Science》更多>>
相关基金:国家自然科学基金更多>>
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PLA_(2) mediates the innate immune response in Asian corn borer, Ostrinia furnacalis被引量:3
《Insect Science》2022年第1期245-258,共14页Jia-Yue Ji Zhao-Hua Yin Sha-Sha Zhang Dong-Xu Shen Chun-Ju An 
This work was supported by the National Nature Science Foundation of China(31672361);the National Key R&D Program of China(2019YFE0120400).
The eicosanoid signaling pathway mediates insect immune reactions to a wide range of stimuli. This pathway begins with the biosynthesis of arachidonic acid (AA) from the hydrolysis of phospholipids catalyzed by phosph...
关键词:eicosanoid signal pathway innate immune response Ostrinia furnacalis phospholipase A_(2)(PLA_(2)) 
Postpartum meloxicam administration alters plasma haptoglobin, polyunsaturated fatty acid, and oxylipid concentrations in postpartum ewes
《Journal of Animal Science and Biotechnology》2020年第4期1047-1060,共14页Katie EOlagaray Barry J.Bradford Lorraine M.Sordillo Jeffery C.Gandy Laman K.Mamedova Turner H.Swartz Trey D.Jackson Emma K.Persoon Caitlin S.Shugart Curtis R.Youngs 
funded by a Let’s Grow grant through the American Sheep Industry。
Background: Postpartum inflammation is a natural and necessary response;however, a dysfunctional inflammatory response can be detrimental to animal productivity. The objective of this study was to determine the effect...
关键词:EICOSANOID Inflammation LACTATION Nonsteroidal anti-inflammatory drug Sheep 
Cytochrome P450 monooxygenase-mediated eicosanoid pathway:A potential mechanistic linkage between dietary fatty acid consumption and colon cancer risk
《Food Science and Human Wellness》2019年第4期337-343,共7页Weicang Wang Jianan Zhang Guodong Zhang 
This research is supported by a new faculty start-up from the University of Massachusetts Amherst,USDA NIFA2016-67017-24423,USDA NIFA 2019-67017-29248,USDA/HatchMAS00492,and NIH/NCIR03 CA218520(to G.Z.).
Human consumption of linoleic acid(LA,18:2ω-6,abundant in vegetable oils)is very high.Animal experiments showed that excessive LA intake increased azoxymethane-induced colon tumorigenesis,however,the impact of excess...
关键词:Linoleic acid Polyunsaturated fatty acids ω-3 Fatty acids Colon cancer Colonic inflammation Cytochrome P450 EICOSANOIDS 
Dietary arachidonate in milk replacer triggers dual benefits of PGE2 signaling in LPS-challenged piglet alveolar macrophages被引量:1
《Journal of Animal Science and Biotechnology》2019年第2期435-448,共14页Kathleen R.Walter Xi Lin Sheila K.Jacobi Tobias Kaser Debora Esposito Jack Odle 
funded in part by the North Carolina State University Agricultural Foundation,USDA-NIFA Animal Health Program
Background: Respiratory infections challenge the swine industry, despite common medicinal practices. The dual signaling nature of PGE2(supporting both inflammation and resolution) makes it a potent regulator of immune...
关键词:Arachidonic acid CYCLOOXYGENASE EICOSANOID Eicosapentaenoic acid Inflammation Lipid mediator class switch LPS LIPOXIN Porcine alveolar macrophage 
Nutrition and metabolism in poultry: role of lipids in early diet被引量:5
《Journal of Animal Science and Biotechnology》2016年第3期312-320,共9页Gita Cherian 
the National Research Initiative of the USDA Cooperative State Research,Education and Extension Service,grant number2004-35204-14654,Oregon State University Experiment Station Hatch fund,Oregon State University Animal Health Fund,and Walther H.Ott Professorship in Poultry Science awarded to G.Cherian
Modern strains of broiler chickens are selected for fast growth and are marketed anywhere from 36 to 49 days after a21-day incubational period. For a viable healthy chick, all the necessary nutrients required for grow...
关键词:Chick Docosahexaenoic acid Early diet Egg Eicosanoid Embryo Essential fatty acids 
Genomic,Lipidomic,and Metabolomic Analysis of Cyclooxygenase-null Cells:Eicosanoid Storm,Cross Talk,and Compensation by COX-1
《Genomics, Proteomics & Bioinformatics》2016年第2期81-93,共13页Abul B.M.M.K.Islam Mandar Dave Sonia Amin Roderick V.Jensen Ashok R.Amin 
supported in part by NIH(Grant No.AR 47206-03)
The constitutively-expressed cyclooxygenase 1(COX-1) and the inducible COX-2 are both involved in the conversion of arachidonic acid(AA) to prostaglandins(PGs).However,the functional roles of COX-1 at the cellul...
关键词:PROSTAGLANDINS Metabolomics Lung fibroblasts Genomies Inflammation 
Eicosanoid pathway in colorectal cancer:Recent updates被引量:4
《World Journal of Gastroenterology》2015年第41期11748-11766,共19页Sinem Tuncer Sreeparna Banerjee 
Supported by The TüBITAK project,No.113S935(to Banerjee S)
Enzymatic metabolism of the 20 C polyunsaturated fatty acid(PUFA) arachidonic acid(AA) occurs via the cyclooxygenase(COX) and lipoxygenase(LOX) pathways, and leads to the production of various bioactive lipids termed ...
关键词:EICOSANOIDS Cydlooxygenase LIPOXYGENASE INFLAMMATION Colorectal cancer 
Involvement of eicosanoids in the pathogenesis of pancreatic cancer: the roles of cyclooxygenase-2 and 5-lipoxygenase被引量:10
《World Journal of Gastroenterology》2014年第31期10729-10739,共11页Lawrence M Knab Paul J Grippo David J Bentrem 
The interplay between inflammation and cancer progression is a growing area of research. A combination of clinical, epidemiological, and basic science investigations indicate that there is a relationship between infla...
关键词:Arachidonic acid EICOSANOID CYCLOOXYGENASE-2 5-LIPOXYGENASE Pancreatic cancer Inflammation 
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