POLYAMIDOAMINE

作品数：15被引量：19H指数：3
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相关领域：医药卫生理学更多>>
相关作者：靳涛吕海亮王恒蔡启良蔺亚晖更多>>
相关机构：山东科技大学中国医学科学院北京协和医学院武汉工程大学中国药科大学更多>>
相关期刊：《Chinese Journal of Biomedical Engineering(English Edition)》《Regenerative Biomaterials》《Science China Chemistry》《International Journal of Ophthalmology(English edition)》更多>>
相关基金：国家自然科学基金北京市自然科学基金国家教育部博士点基金国家重点基础研究发展计划更多>>
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Dopamine-mimetic-coated polyamidoamine-functionalized Fe_(3)O_(4) nanoparticles for safe and efficient gene delivery
《Frontiers of Materials Science》2023年第1期141-152,共12页Liang Liu Chaobing Liu Zhaojun Yang Yiran Chen Xin Chen Jintao Guan 
This work was supported in part by the National Natural Science Foundation of China(Grant No.21602166);the Natural Science Foundation of Hubei Province(Grant No.2020CFB760);the Research and Innovation Initiatives of WHPU(Grant No.2021Y11).
Fe_(3)O_(4) nanoparticles(NPs)are widely used in the construction of drug and gene delivery vectors because of their particular physicochemical properties.Surface modification can not only reduce the cytotoxicity of F...
关键词：gene vector nanoparticle POLYDOPAMINE gene transfection 
A green light-enhanced cytosolic protein delivery platform based on BODIPY-protein interactions被引量：1
《Nano Research》2023年第1期1042-1051,共10页Yang Zhou Yifan Gao Li Pang Weirong Kang Kwan Man Weiping Wang 
This work was supported by the Research Grants Council of Hong Kong(Early Career Scheme,No.27115220);Ming Wai Lau Centre for Reparative Medicine Associate Member Program.
Development of cytosolic protein delivery platforms brings new possibilities for various incurable diseases.Strategies based on polymer/protein self-assembly have shown their potential in protein delivery.However,vers...
关键词：photoresponsive nanoparticles intracellular delivery protein delivery polyamidoamine(PAMAM) boron-dipyrromethene(BODIPY) 
A polyamidoamine(PAMAM)derivative dendrimer with high loading capacity of TLR7/8 agonist for improved cancer immunotherapy被引量：3
《Nano Research》2022年第1期510-518,共9页Jia-Si Wu Jia-Xian Li Na Shu Qi-Jia Duan Qi-Song Tong Jing-Yang Zhang Yong-Cong Huang Si-Yu Yang Zhi-Bin Zhao Jin-Zhi Du 
supported by National Key R&D Program of China(No.2017YFA0205600);Guangdong Natural Science Funds for Distinguished Young Scholar(No.2017A030306018);National Natural Science Foundation of China(Nos.51922043 and 31771091);Guangdong Provincial Programs(Nos.2017ZT07S054 and 2017GC010304);the Science and Technology Program of Guangzhou(No.201902020018),and Fundamental Research Funds for Central Universities.
Tumor associated macrophages(TAMs)tend to exhibit tumor-promoting M2 phenotype and contribute to the development of immunosuppressive microenvironment of solid tumors.Reprograming TAMs from M2 into tumoricidal M1 phen...
关键词：poly(amidoamine)(PAMAM)dendrimer drug delivery tumor-associated macrophage macrophage repolarization cancer immunotherapy 
A new strategy of enhancing absorptivity and safety for evodiamine: polyamidoamine derivatives modified by polyethylene glycol chain
《Traditional Medicine Research》2021年第2期100-110,共11页Yao-Chun Gao Yuan-Sheng Lao Meng-Xue Zhang Nan Li Chen-Yang Wu Zheng-Qi Dong 
This research was funded by National Major Scientific and Technological Special Project for“Significant New Drugs Development”(No.2015ZX09501005);Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(No.2016-I2M-1-012).
Background:Traditional Chinese medicine involves complex ingredients and mixtures of ingredients that often exhibit low bioavailability,and excipients are often lacking to increase the absorption-enhancing effects.Thi...
关键词：Polyamidoamine dendrimers Polyethylene glycol Intestinal absorption enhancer BIOAVAILABILITY EVODIAMINE Fructus Evodiae 
Efficient GSH delivery using PAMAM-GSH into MPP-induced PC12 cellular model for Parkinson’s disease被引量：3
《Regenerative Biomaterials》2016年第5期299-307,共9页Hong-Ji Sun Yan Wang Tong Hao Chang-Yong Wang Qi-Yu Wang Xiao-Xia Jiang 
This study was supported by Program of International Scientific and Technological Cooperation and Exchanges of China(No.2013DFG30680);National Key Research and Development Program(2016YFC1101303);Beijing Natural Science Foundation(No.7162142);National Natural Science Foundation of China(No.81272912).
Glutathione(GSH)depletion has been an important contributor to the dysfunction of dopamine neurons.Polyamidoamine-GSH(PAMAM-GSH)was synthesized and the delivery effect of GSH into PC12 cells was tested.MTT assessment ...
关键词：POLYAMIDOAMINE GLUTATHIONE MPP PC12 cells Parkinson’s disease 
Multiarm Star Poly(ε-caprolactone) with Hyperbranched Polyamidoamine as Core Capable of Selective Accommodating Cationic or Anionic Guests被引量：1
《Chinese Journal of Polymer Science》2015年第6期920-930,共11页Chen Zhan Si Li Jin Cui 陈宇 
financially supported by the National Natural Science Foundation of China(Nos.21074088 and 31201426)
Hyperbranched polyamidoamines （HPAs） were directly employed as macroinitiators to initiate the Sn（Oct）2 catalyzed ring-opening polymerization of ε-caprolactone （CL）, resulting in multiarm star copolymers with p...
关键词：NANOCARRIER HYPERBRANCHED POLYAMIDOAMINE Poly（ε-caprolactone） Star polymers. 
Poly(styrene-co-divinylbenzene)-PAMAM-IDA chelating resin: Synthesis, characterization and application for Ni(II) removal in aqueous被引量：1
《Journal of Central South University》2014年第9期3479-3484,共6页刘耀驰 李学农 王春志 孔秀 周荔子 
Project(51074192)supported by the National Natural Science Foundation of China
PS-PAMAM-IDA chelating resins were prepared by low-generations of polyamidoamine(PAMAM) and then chloroacetic acid functionalizing commercially available ammoniated polystyrene matrix, to preconcentrate Ni2+ from synt...
关键词：chelating resin POLYAMIDOAMINE iminodiacetic acid properties Ni（II） 
Ab initio Study of Complexation Process between Poly（amido-amine） and Nano-Silicon Dioxide被引量：3
《Chinese Journal of Chemical Physics》2013年第3期277-286,I0003,共11页靳涛 吕海亮 
To understand better the molecular-level details of ≡Si＋ （SC） or ≡SiO- （SOA） ion group to -NH2 teminated poly（amido-amine） dendrimers in the gas phase, density functional theory is used to optimize the minimu...
关键词：POLYAMIDOAMINE Activation energy Transition state Density functionaltheory 
The Modification of Poly amidoamine (PAMAM-G0.5) by Cytosine
《Engineering（科研）》2012年第10期103-105,共3页Omid Louie Abdolhossien Massoudi Hooshang Vahedi Hajar Asadi Sami Sajjadifar 
The half generation Poly(amidoamine) (PAMAM) dendrimers was synthesized and characterized and modification by heterocyclic DNA base (Cytosine) . The conjugated Cytosine? modified detected by FT-IR, 1H NMR, 13C NMR and...
关键词：Component POLYAMIDOAMINE PAMAM CYTOSINE 
Effect of VEGF-targeted antisense gene therapy on retinoblastoma cell line SO-RB50 in vitro and in vivo被引量：1
《International Journal of Ophthalmology(English edition)》2012年第4期440-447,共8页Guo-Hong Xin, Ya-Jie Cheng 
AIM: To evaluate the possibility of generation 4 polyamidoamine (G4PAMAM) dendrimers acting as the delivery system of vascular endothelial growth factor (VEGF) antisense oligodeoxynucleotides (VEGFASODN), and to inves...
关键词：vascular endothelial growth factor antisense oligonucleotides generation 4 polyamidoamine angiogenesis gene therapy RETINOBLASTOMA 
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