The binding properties of neural cell adhesion molecule are modulated by a polysialic acid moiety. This plays an important role in the migration of adult born neuroblasts from their area of origin, the subventricular ...
The University Natural Science Research major Project of Jiangsu Province(Grant No.16KJA310006)
Aging affects the nervous system as well as other organs.In our study,we aimed to study the pharmacological effects and mechanism of porcine placental peptides(PPP)in aging process,and to observe the changes of neurob...
supported by the National Natural Science Foundation of China,No.81200937(to QY)
Astrocytes, the major component of blood-brain barriers, have presented paradoxical profiles after cerebral ischemia and reperfusion in vivo and in vitro. Our previous study showed that sevoflurane preconditioning imp...
supported by the grants from the Ministry of Science and Technology (2016YFA0501000);the National Science Foundation of China to YQZ (31490592) and AY (31271121)
Mutations in long-chain acyl-CoA synthetase 4 (ACSL4) are associated with non-syndromic X-linked intellectual disability (ID). However, the neural functions of ACSL4 and how loss of ACSL4 leads to ID remain largely un...
supported by the National Institutes of Health[U01-NS094340(Cullen),F31-NS090746(Katiyar)&F32-NS103253(O’Donnell)];University of Pennsylvania[Center for Undergraduate Research&Fellowships(Panzer)];Michael J.Fox Foundation[Therapeutic Pipeline Program#9998(Cullen)];Department of Veterans Affairs[RR&D Merit Review I01-RX001097(Cullen)&BLR&D Merit Review I01-BX003748(Cullen)];the U.S.Army Medical Research and Materiel Command[W81XWH-16-1-0796(Cullen)]
New neurons are integrated into the circuitry of the olfactory bulb throughout the lifespan in the mamma- lian brain--including in humans. These new neurons are born in the subventricular zone and subsequently mature ...
supported by a grant from the Research Project of Fujian Provincial Health and Family Planning Commission of China,No.2014-ZQN-JC-32;a grant from the Project of Fujian Province Office of Education of China,No.JZ160442;the Natural Science Foundation of Fujian Province of China,No.2018J01855;a grant from the Platform for Preclinical Studies of Traditional Chinese Medicine and Quality Control Engineering Technology Research Center of Fujian Province of China,No.2009Y2003
Recovery following stroke involves neurogenesis and axonal remodeling within the ischemic brain. Gualou Guizhi decoction (GLGZD) is a Chinese traditional medicine used for the treatment of post-stroke limb spasm. GL...
Background: Glehnia littoralis has been used for traditional Asian medicine, which has diverse therapeutic activities. However, studies regarding neurogenic effects of G. littoralis have not yet been considered. Ther...
supported by Hallym University Specialization Fund,No.HRF-S-12
Oenanthe javanica is an aquatic perennial herb that belongs to theOenanthe genus in Apiaceae family, and it displays well-known medicinal properties such as protective effects against glu-tamate-induced neurotoxicity....
supported by the National Research Foundation of Korea(NRF);funded by the Ministry of Education,Science and Technology,No.2010-0010580;Basic Science Research Program through the National Research Foundation of Korea(NRF);funded by the Ministry of Science,ICT and future Planning,No.NRF-2013R1A2A2A01068190
Long-term administration of scopolamine, a muscarinic receptor antagonist, can inhibit the survival of newly generated cells, but its effect on the proliferation, differentiation and migration of nerve cells in the ad...
Background Hippophae rhamnoides L.(HL) exerts antioxidant activities against various oxidative stress conditions.In this study,we investigated effects of extract from HL leaves (HLE) on cell proliferation and neur...