CROSS-TALK

作品数：129被引量：807H指数：12
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基于GEO芯片联合网络药理学探讨当归饮子治疗慢性荨麻疹的cross-talk及miRNA-mRNA机制被引量：3
《云南中医学院学报》2020年第4期79-86,共8页包成通 魏歆然 张依依 钟峰 匡泓俊 牛子青 刘小娟 王璐 李俊熙 章薇 
“十三五”国家重点研发计划中医药现代化研究重点专项“针灸优势病种疗效评价国际合作研究”项目(2017YFC1703605);国家中医药管理局湖湘五经配伍针推学术流派传承工作室项目(LP0118041-Z1);湖南省中医药管理局重点项目(201423);国家重点基础研究发展计划(973计划)(2015CB554502);湖南中医药大学中医学一流学科开放基金项目(2018ZYX37)。
目的采用GEO芯片联合网络药理学的研究方法,初步探讨当归饮子治疗慢性荨麻疹(CU)的cross-talk及miRNA-mRNA机制,为后续实验研究提供理论基础。方法采用R语言limma包对GSE57178芯片进行差异分析;采用TCMSP、TCMID、PubChem、String、DAVI...
关键词：GEO 当归饮子 慢性荨麻疹 网络药理学 CROSS-TALK MIRNA 
The cross-talk between methylation and phosphorylation in lymphoid-specific helicase drives cancer stem-like properties
《Signal Transduction and Targeted Therapy》2020年第1期670-683,共14页Na Liu Rui Yang Ying Shi Ling Chen Yating Liu Zuli Wang Shouping Liu Lianlian Ouyang Haiyan Wang Weiwei Lai Chao Mao Min Wang Yan Cheng Shuang Liu Xiang Wang Hu Zhou Ya Cao Desheng Xiao Yongguang Tao 
supported by the National Natural Science Foundation of China[81672991 and 81874139 to S.L.,81872285 to Y.S.,81728014 to Y.T.,81672787 to Y.T.,81672307 to X.W,81772927 to D.X.];the National Basic Research Program of China[2015CB553903 to Y.T.];the Overseas Expertise Introduction Project for Discipline Innovation(111 Project,No.111-2-12);the Fundamental Research Funds for the Central Universities[2017zzts206 to N.L.].
Posttranslational modifications(PTMs)of proteins,including chromatin modifiers,play crucial roles in the dynamic alteration of various protein properties and functions including stem-cell properties.However,the roles ...
关键词：CANCER residue PHOSPHORYLATION 
Experimental Study of Two-Neutron Correlation in ~8He^+
《Plasma Science and Technology》2012年第6期539-542,共4页肖军 叶沿林 游海波 杨再宏 曹中鑫 江栋兴 郑涛 华辉 李智焕 葛俞成 李湘庆 楼建玲 李阔昂 李奇特 乔锐 陈瑞九 
supported by the National Basic Research Program of China (No. 2007CB815002);National Natural Science Foundation of China(Nos. 11035001, 10775003, 10827505, 10821140159)
A neutron detector array was used in a breakup reaction experiment at RIKEN with an 82.5 MeV/u SHe beam impinging on the CH2 and C targets. The array was calibrated using the cosmic ray, the 7 ray from the 6He＋Pb rea...
关键词：SHE NEUTRON CROSS-TALK two-neutron correlation 
Cross-lenticular lens array for full parallax 3-D display with crosstalk reduction被引量：3
《Science China(Technological Sciences)》2012年第3期735-742,共8页XIE HongBin ZHAO Xing YANG Yong BU Jing FANG ZhiLiang YUAN XiaoCong 
supported by the National Basic Research Program of China ("973" Project) (Grant No. 2010CB327702)
As a 3-D display technology,stereoscopic imaging with lenticular lens sheet can only offer viewers the horizontal parallax.To reconstruct the 3-D image with parallax in both horizontal and vertical directions,the full...
关键词：3-D display full parallax cross-lenticular lens array CROSS-TALK 
Cross-talk between NMDA and GABA_A receptors in cultured neurons of the rat inferior colliculus被引量：9
《Science China(Life Sciences)》2011年第6期560-566,共7页CONG DanNi TANG ZhengQuan LI LongZhu HUANG YiNa WANG Jun CHEN Lin 
supported by the National Basic Research Program of China (Grant Nos. 2011CB504506 and 2007CB512306);the National Natural Science Foundation of China (Grant Nos. 30970977 and 30730041);the Knowledge Innovation Project of the Chinese Academy of Sciences (Grant No. KSCX1-YW-R-36)
Neuronal ion channels of different types often do not function independently but will inhibit or potentiate the activity of other types of channels,a process called cross-talk.The N-methyl-D-aspartate receptor (NMDA r...
关键词：inferior colliculus N-methyl-D-aspartate receptor γ-aminobutyric acid type A receptor whole-cell patch-clamp CROSS-TALK 
Brownian dynamics simulation of the cross-talking effect among modified histones on conformations of nucleosomes
《Chinese Physics B》2010年第4期461-468,共8页段兆文 李伟 谢平 窦硕星 王鹏业 
Project supported by the National Natural Science Foundation of China (Grants Nos. 10834014 and 10674173);the National Basic Research Program of China (Grant No. 2009CB930704)
Using Brownian dynamics simulation, we studied the effect of histone modifications On conformations of an array of nucleosomes in a segment of chromatin. The simulation demonstrated that the segment of chromatin shows...
关键词：NUCLEOSOME histone modification DNA Brownian dynamics 
Cross-talk between oxidative stress and modifications of cholinergic and glutaminergic receptors in the pathogenesis of Alzheimer＇s disease被引量：12
《Acta Pharmacologica Sinica》2008年第7期773-780,共8页Zhi-zhong GUAN 
This work was supported financially by grants from the Foundation of Ministry of Science and Technology of China （No 2004DFB02800 and 2006DFA33530）, the Chinese National Natural Science Foundation （No 30460045）. and the Foundation of Guizhou Province of China （No [2006] 400107, [2006] 52, and [2006] 6015）.
Alzheimer＇s disease （AD） is the most common neurodegenerative disorder, and its pathogenesis is likely to be associated with multiple etiologies and mechanisms in which oxidative stress and deficits of neurotransmi...
关键词：Alzheimer＇s disease oxidative stress nicotinicreceptor muscarinic receptor N-methyl-D-aspartate receptor 
Cross-talk between calcium-calmodulin and nitric oxide in abscisic acid signaling in leaves of maize plants被引量：6
《Cell Research》2008年第5期577-588,共12页Jianrong Sang Aying Zhang Fan Lin Mingpu Tan Mingyi Jiang 
Acknowledgments This work was supported by the Major State Basic Research Program of China （grant no. 2003CB 114302 to M Jiang）, the National Natural Science Foundation of China （grant no. 30571122 to M Jiang）, and the Youth Scientific and Technological Innovation talent Project of Jiangsu Province （grant no. BK2007575 to A Zhang）.
Using pharmacological and biochemical approaches, the signaling pathways between hydrogen peroxide （H2O2）, calcium （Ca^2＋）-calmodulin （CAM）, and nitric oxide （NO） in abscisic acid （ABA）-induced antioxidant ...
关键词：abscisic acid antioxidant defense CALMODULIN cytosolic calcium nitric oxide nitric oxide synthase Zea mays 
Cross-talk between Natural Killer Cells and Dendritic Cells in Innate and Adaptive Immunity
《Journal of Microbiology and Immunology》2004年第3期155-161,共7页韩岩梅 曹雪涛 
This work was supported by grants from the National Natural Science Foundation of China (30121002; 30490240) and National Key Basic Research Program of China (2001CB510002)
关键词：KILLER IMMUNITY IMMUNITY INNATE CYTOKINE activatin 
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