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ENONE: 作品数：22被引量：4H指数：1; 导出分析报告; 相关领域：理学医药卫生更多>>; 相关作者：周成合更多>>; 相关机构：西南大学更多>>; 相关期刊：《Science China Chemistry》《Chemical Research in Chinese Universities》《Chinese Journal of Structural Chemistry》《合成化学》更多>>; 相关基金：国家自然科学基金重庆市自然科学基金湖南省教育厅科研基金更多>>

Discovery of Alkaloid Quinazolone-Derived Imidazolenones with Novel Structural Scaffolds of Multitargeting Antibacterial Potential被引量：1: 《Chinese Journal of Chemistry》2023年第24期3645-3661,共17页Jie Dai Narsaiah Battini Zhong-Lin Zang Yan Luo Cheng-He Zhou; supported in part by grants from the National Natural Science Foundation of China(NSFC,No.21971212);the Key Project of Innovation Research 2035 Pilot Plan of Southwest University,China(SWU-XDZD22007);the Research Fund for International Young Scientists from International(Regional)Cooperation and Exchange Program of NSFC(21850410447);the Research Funds for the Central Universities of China(XDJK2020C031).; Alkaloids are one of the prominent members in the development of new antimicrobial agents.This work discovered a class of alkaloid quinazolone-derived imidazolenones as novel structural type of antibacterial agents wi...; 关键词：Quinazolone IMIDAZOLE ANTIBACTERIAL ENONE DNA

Transition metal-free dearomatization of halonaphthols with C(sp^(3))-electrophiles: 《Chinese Chemical Letters》2022年第5期2411-2414,共4页Naichen Zhang Yuanzhi Ye Lu Bai Jingjing Liu Han Wang Xinjun Luan; The National Natural Science Foundation of China(Nos.21901203,22171225,21925108);the Education Department of Shaanxi Province(No.20JK0934)are acknowledged for financial support.; The first intermolecular electrophilic dearomatization of halonaphthols with benzyl/allyl bromides is described. Halonaphthols are used as carbon-nucleophiles in dearomatization to form three-dimensional cyclic enones...; 关键词：Halonaphthol Fluoronaphol BENZYLATION ALLYLATION Cyclic enone

Asymmetric catalytic 1,3-dipolar cycloaddition ofα-diazoesters for synthesis of 1-pyrazoline-based spirochromanones and beyond: 《Science China Chemistry》2021年第8期1355-1360,共6页Peng Zhao Zegong Li Jun He Xiaohua Liu Xiaoming Feng; This work was supported by the National Natural Science Foundation of China(U19A2014,21890723).; A highly enantioselective 1,3-dipolar cycloaddition ofα-substituted diazoesters with exocyclic enones was achieved with chiral scandium(III)/N,N’-dioxide complex as the catalyst.This protocol provided a facile and e...; 关键词：asymmetric synthesis α-diazoesters 1 3-dipolar cycloaddition exocyclic enone PYRAZOLINE

Enantioselective Hydrogenation of Endocyclic Enones:the Solution to a Historical Problem被引量：1: 《Chinese Journal of Chemistry》2021年第4期933-936,共4页Qiwei Lang Huaxin Yang Guoxian Gu Qiang Feng Jialin Wen Xumu Zhang; This project was financially supported by the Science,Technology and Innovation Commission of Shenzhen(Nos.KQTD20150717103157174,JCYJ20170817104350391);the National Natural Science Foundation of China(No.21801118);the Guangdong Provincial Key Laboratory of Catalysis(No.2020B121201002).; Main observation and conclusion The enantioselective hydrogenation of endocyclic enones has been a historical problem for homogeneous catalysis.We herein report an efficient method to reduce endocyclic enones with mol...; 关键词：Asymmetric catalysis HYDROGENATION Cyclic enone RHODIUM Citral reduction

Diverse synthesis of the C ring fragment of bryostatins via Zn/Cu-promoted conjugate addition of α-hydroxy iodide with enone: 《Chinese Chemical Letters》2021年第1期1-4,共4页Zhiwen Chu Ruiqi Tong Yufan Yang Xuanyi Song Tian bao Hu Yu Fan Chen Zhao Lu Gao Zhenlei Song; the financial support from the National Natural Science Foundation of China(No.21921002);the NationalScience and Technology Major Project of the Ministry of Science and Technology of the People’s Republic of China(No.2018ZX09711001-005-004);the Fundamental Research Funds for the Central Universities(No.2012017yjsy210)。; A convergent approach to 1,5-hydroxy ketones,the general precursors for constructing the C ring of bryostatins,has been developed via a Zn/Cu-promoted conjugate addition of a-hydroxy iodides with enones.The reaction l...; 关键词：Bryostatins Zn/Cu-promoted conjugate addition α-Hydroxy iodide ENONES 1 5-Hydroxy ketones

Oleylamine-catalyzed Tandem Knoevenagel/Michael Addition of 1,3-Cyclohexanediones with Aromatic Aldehydes: 《Chemical Research in Chinese Universities》2018年第2期186-190,共5页HE Xinwei WU Yuhao FAN Chenli LU Peng ZUO Youpeng SHANG Yongjia; Supported by the National Natural Science Foundation of China（Nos.21772001, 21372008）, the Natural Science Foundation of Education Administration of Anhui Province, China（No.KJ2016A267）, the Special and Excellent Research Fund of Anhui Normal Universit and the Doctoral Scientific Research Foundation of Anhui Normal University, China（No.2016XJJ110）.; A convenient and efficient method was developed for the synthesis of 2,2＇-（arylmethylene）bis（3-hydrox- ycyclohex-2-enone） derivatives via the oleylamine-catalyzed tandem Knoevenagel/Michael addition reactions of ...; 关键词：2 2＇-（Arylmethylene）bis（3-hydroxycyclohex-2-enone） Knoevenagel condensation Michael addition OLEYLAMINE Tandem reaction

Synthesis of trifluoromethyl-/cyclopropyl-substituted 2-isoxazolines by DBU-promoted domino reaction: 《Chinese Chemical Letters》2017年第8期1780-1783,共4页Xiao-Dong Liu Hai-Yan Ma Chun-Hui Xing Long Lu; Supports from the National Natural Science Foundation of China (Nos. 21272257, 21274041 and 21474028); NTrifluoromethyl and cyclopropyl substituted 2-isoxazolines were synthesized via a DBU-promoted domino reaction of β-trifluoromethyl-/β-cyclopropyl-substituted enones with hydroxylamine. The domino reaction consists...; 关键词：Isoxazoline Enone Michael addition Cyclization Domino reaction

Study of Free-Radical Processes during Rotenone Modeling of Parkinson Disease: 《Journal of Biophysical Chemistry》2016年第1期1-8,共8页Narine A. Ghazaryan Lusine A. Ghulikyan Vergine A. Chavushyan Naira M. Ayvazyan; The study has shown free radical processes during modeling of Parkinson Disease (PD) with rotenone. We isolated striatum, brainstem, neocortex, cerebellum, spinal cord, thymus, heart, and liver of rats after rotenone ...; 关键词：Parkinson’s Disease ROTENONE CHEMILUMINESCENCE Thio-Barbituric Acid Test Superoxide Dismutase Activity

Synthesis of Novel Tartaric Acid-derived Chiral Phosphite Ligands and Their Application in the Cu-catalyzed Conjugate Addition of Diethylzinc to Cyclic Enones: 《Chemical Research in Chinese Universities》2015年第5期756-760,共5页PANG Zengbo XING Aiping WANG Lailai; Supported by the National Natural Science Foundation of China （Nos.20773147, 21073211, 21174133）.; Five novel tropos （3R,4R）- and/or （3S,4S）-N-benzyltartarimide-derived biphenylphosphite ligands were synthesized and applied in the Cu-catalyzed asymmetric conjugate addition of diethylzinc to cyclic enones with u...; 关键词：L-（＋）- and/or D-（-）-tartaric acid Phosphite ligand 1 4-Conjugate addition Copper salt Cyclic enone

Synthesis and Antitussive Effect of New Hydantoin Compounds: 《Chemical Research in Chinese Universities》2013年第1期76-81,共6页ZHANG Qun-li SONG Li-jun WANG En-si; A series of new hydantoin compounds was synthesized with 3-bromo phenylacetic acid and 3,4-dimethylbromobenzene as starting material, 7-bromo-2-tetralone and 2-bromo-5,6,8,9-tetrahydro-7-benzocycloheptenone as interme...; 关键词：HYDANTOIN 2-Bromo-5 6 8 9-tetrahydro-7-benzocycloheptenone Bioactivity 7-Bromo-2-tetralone Anti-tussive effect

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