FACTOR-BETA

作品数：13被引量：65H指数：5
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相关领域：医药卫生更多>>
相关机构：浙江大学医学院附属第二医院更多>>
相关期刊：《Chinese Journal of Integrative Medicine》《World Journal of Gastroenterology》《Surgical Science》《World Journal of Hepatology》更多>>
相关基金：安徽省自然科学基金国家自然科学基金更多>>
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Tousled-like kinase 1 promotes gastric cancer progression by regulating the tumor growth factor-beta signaling pathway
《World Journal of Gastroenterology》2023年第44期5919-5934,共16页Ruo-Chuan Sun Jing Li Ya-Xian Li Hui-Zhen Wang Emre Dal Ming-Liang Wang Yong-Xiang Li 
Supported by the Key Programs of the Educational Commission of Anhui Province,No.2023AH053313;the Research Project of Higher Education in Anhui Province in 2022,No.2022AH051192.
BACKGROUND The role of Tousled-like kinase 1(TLK1)in in gastric cancer(GC)remains unclear.AIM To investigate the expression,biological function,and underlying mechanisms of TLK1 in GC.METHODS We measured TLK1 protein ...
关键词：Gastric cancer Tousled-like kinase 1 Tumor growth factor-beta Tumour progression Targeted therapy 
Leech-Centipede Granules Suppress EndMT to Improve Erectile Dysfunction in Rats with Diabetes Mellitus via TGF-β/Smad Pathway被引量：1
《Chinese Journal of Integrative Medicine》2023年第1期28-36,共9页ZHANG Hui FENG Chu-hui HE Shan DENG Ming-xia MENG Hao CHEN Ming LIU Hong 
Supported by the Scientific Research Project of the Traditional Chinese Medicine Bureau of Guangdong Province,China(Nos.20211136 and 20221086)。
Objective:To investigate whether Leech-Centipede(LC) Granules can improve erectile function in rats with diabetes mellitus-associated erectile dysfunction(DMED) through endothelial-to-mesenchymal transition(EndMT) inh...
关键词：Leech-Centipede Granules erectile function diabetes mellitus endothelial cell endothelial-to-mesenchymal transition tumor growth factor-beta/Smad pathway 
Linggui Zhugan Decoction(苓桂术甘汤)Inhibits Ventricular Remodeling after Acute Myocardial Infarction in Mice by Suppressing TGF-β1 Smad Signaling Pathway被引量：22
《Chinese Journal of Integrative Medicine》2020年第5期345-352,共8页WANG Liang SHI Hui HUANG Jin-ling XU Shan LIU Pei-pei 
Supported by the National Natural Science Foundatio of China(No.30973707,81373533,81202631);the Natural Science Foundation of Anhui Province(NO.1508085QH192,1608085QH222)。
Objective:To investigate the inhibitory effect of Linggui Zhugan Decoction(LZD,苓桂术甘汤)on the ventricular remodeling(VR)after acute myocardial infarction(AMI)and related mRNA and proteins expression in transforming...
关键词：Linggui Zhugan DECOCTION acute myocardial INFARCTION VENTRICULAR REMODELING transtorming growth FACTOR-BETA 1/Smad signaling PATHWAY Chinese medicine 
Correlation between NF-κB, TGF-β1 in patients with left ventricular diastolic failure and left ventricular remodeling被引量：1
《Journal of Hainan Medical University》2017年第3期29-31,共3页Wan Chen You-Mei Li Yun-Feng Shou 
Objective:To investigate the expression changes of nuclear factor-kappa B (NF-κB) and transforming growth factor-beta (TGF-β1) in patients with left ventricular failure and its correlation with left ventricular remo...
关键词：VENTRICULAR REMODELING Nuclear factor-κB TRANSFORMING growth FACTOR-BETA Heart FAILURE 
Platelet-rich plasma increases transforming growth factor-beta1 expression at graft-host interface following autologous osteochondral transplantation in a rabbit model被引量：8
《World Journal of Orthopedics》2015年第11期961-969,共9页Lorraine A Boakye Keir A Ross John M Pinski Niall A Smyth Amgad M Haleem Charles P Hannon Lisa A Fortier John G Kennedy 
Supported by Arteriocyte Inc.;the Ohnell Family Foundation;and Mr.and Mrs.Michael J Levitt
AIM: To explore the effect of platelet-rich plasma on protein expression patterns of transforming growth factor-beta1(TGF-β1) in cartilage following autologous osteochondral transplantation(AOT) in a rabbit knee cart...
关键词：PLATELET rich plasma TRANSFORMING growth FACTOR-BETA AUTOLOGOUS OSTEOCHONDRAL transplantation 
Mechanisms of fibrogenesis in liver cirrhosis:The molecular aspects of epithelial-mesenchymal transition被引量：18
《World Journal of Hepatology》2014年第4期207-216,共10页Sun-Jae Lee Kyung-Hyun Kim Kwan-Kyu Park 
Supported by The National Research Foundation of Korea Grant funded by the Korean Government,No.2012R1A1A401015639
Liver injuries are repaired by fibrosis and regeneration.The cause of fibrosis and diminished regeneration,especially in liver cirrhosis,is still unknown.Epithelialmesenchymal transition(EMT) has been found to be asso...
关键词：Epithelial-mesenchymal transition Liver Fibrosis TRANSFORMING growth factor-beta1 Biological markers 
Role of TGF-<i>β</i>in breast cancer bone metastases被引量：5
《Advances in Bioscience and Biotechnology》2013年第10期15-30,共16页Antonella Chiechi David L. Waning Keith R. Stayrook Jeroen T. Buijs Theresa A. Guise Khalid S. Mohammad 
Breast cancer is the most prevalent cancer among females worldwide leading to approximately 350,000 deaths each year. It has long been known that cancers preferentially metastasize to particular organs, and bone metas...
关键词：Transforming Growth FACTOR-BETA TGF-β Breast Cancer BONE Metastasis BONE Small Molecule Inhibitors Antibodies BONE RESORPTION 
Expression of Cyclooxygenase-2 and Transforming Growth Factor-Beta 1 in Patients with the Early Recurrence of Hepatocellular Carcinoma Following Hepatectomy
《Surgical Science》2012年第6期322-331,共10页Takayuki Nakase Masaki Ueno Kazuhisa Uchiyama Nariaki Matsuura Hiroki Yamaue 
Background: Cyclooxygenase-2 (COX-2) and transforming growth factor-beta1 (TGF-β1) are modulated in variety cancers including Hepatocellular carcinoma (HCC). However, there is a paucity of data concerning their role ...
关键词：CYCLOOXYGENASE-2 TRANSFORMING Growth Factor-Beta1 HEPATOCELLULAR Carcinoma Early RECURRENCE HEPATECTOMY 
Hypoxia and cytokines regulate carbonic anhydrase 9 expression in hepatocellular carcinoma cells in vitro被引量：2
《World Journal of Clinical Oncology》2012年第6期82-91,共10页Feray Kockar Hatice Yildrim Rahsan Ilikci Sagkan Carsten Hagemann Yasemin Soysal Jelena Anacker Ahmed Ayad Hamza Dirk Vordermark Michael Flentje Harun M Said 
Supported by Deutsche Forschungsgemeinschaft DFG,VO 871/2-3,to Vordermark D;the IZKF Würzburg,B25,to Hagemenn C;Turkish Research Council(TUBITAK)Project,TBAG 105T326,to Kockar F and Yildrim H;Balikesir University Research Project,2008/15,to Sagkan RI
AIM: To study the expression of carbonic anhydrase(CA) 9 in human hepatocellular carcinoma(HCC) cells.METHODS: We studied CA9 protein, CA9 m RNA and hypoxia-inducible factor-1 alpha(HIF-1α) protein levels in Hep3 B c...
关键词：Angiogenesis Carbonic ANHYDRASE 9 HYPOXIA Hypoxia-inducible factor-1 alpha Oxygen Radiotherapy TRANSFORMING growth FACTOR-BETA TUMOUR microenviroment 
I_κB kinase-beta inhibitor attenuates hepatic fibrosis in mice被引量：8
《World Journal of Gastroenterology》2011年第47期5203-5213,共11页Jue Wei Min Shi Wei-Qi Wu Hui Xu Ting Wang Na Wang Jia-Li Ma Yu-Gang Wang 
Supported by Shanghai Municipal Health Bureau Youth Grant, No. 2008Y032
AIM: To investigate the anti-fibrosis effect of IκB kinase-beta inhibitor (IKK2 inhibitor IMD0354) in liver fibrosis. METHODS: Twenty male C57BL6 mice were divided into four groups. Five high-fat fed mice were inject...
关键词：Liver fibrosis IKK2 inhibitor Nuclear factor-kappa B Tumor growth factor-beta1 INTERLEUKIN-6 Alpha-smooth muscle actin C57BL mouse 
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