CRYSTALLINS

作品数：5被引量：5H指数：1
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相关领域：医药卫生生物学更多>>
相关期刊：《International Journal of Ophthalmology(English edition)》《Neural Regeneration Research》《眼科学报》《World Journal of Biological Chemistry》更多>>
相关基金：国家自然科学基金更多>>
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Srgap2 suppression ameliorates retinal ganglion cell degeneration in mice被引量：2
《Neural Regeneration Research》2023年第10期2307-2314,共8页Yi-Jing Gan Ying Cao Zu-Hui Zhang Jing Zhang Gang Chen Ling-Qin Dong Tong Li Mei-Xiao Shen Jia Qu Zai-Long Chi 
supported by the Notional Natural Science Foundation of China,Nos.81770918 (to ZLC),31871383 (to TL);the Natural Science Foundation of Zhejiang Province,No.LY16H120006 (to ZLC);the Departmental Funds from Wenzhou Medical University,No.89214018 (to ZLC)。
Slit-Robo GTPase-activating protein 2(SRGAP2) plays important roles in axon guidance, neuronal migration, synapse formation, and nerve regeneration. However, the role of SRGAP2 in neuroretinal degenerative disease rem...
关键词：ASTROCYTE CRYSTALLINS intraocular hypertension MICROGLIA mTOR NEUROPROTECTION optic nerve crush optic neuropathy RGC degeneration Srgap2 
Auto-cortex of crystalline lens-induced iris neovascularization被引量：1
《International Journal of Ophthalmology(English edition)》2012年第1期23-27,共5页Lin Liu, Wen-Xin Zhang 
Supported by National Natural Science Foundation of China (No.39870801);Innovative Drug and Technological Development Program of Guangzhou Municipality, China (No.2006Z3-E4091);Guangdong Provincial Medical Science and Technology Research Foundation, China(No.B2006118)
AIM:To investigate auto-cortex of crystalline lens induced iris neovascularization (INV). METHODS: Thirty-six eyes of 36 guinea-pigs were included and divided into three groups randomly in this cohort study. Group A: ...
关键词：IRIS new vessels CRYSTALLINS 
Methionine sulfoxide reductase A: Structure, function and role in ocular pathology被引量：1
《World Journal of Biological Chemistry》2011年第8期184-192,共9页Parameswaran G Sreekumar David R Hinton Ram Kannan 
Supported by Grants from NIH (EY01545, EY03040);The Arnold and Mabel Beckman Foundation (to Hinton DR);a grant to the Department of Ophthalmology by Research to Prevent Blindness
Methionine is a highly susceptible amino acid that can be oxidized to S and R diastereomeric forms of methionine sulfoxide by many of the reactive oxygen species generated in biological systems. Methionine sulfoxide r...
关键词：METHIONINE SULFOXIDE REDUCTASES Hypoxia Protein interaction α CRYSTALLINS NEUROPROTECTION 
Patterns of synuclein expression throughout lens development
《Journal of Biophysical Chemistry》2010年第1期12-18,共7页Irina Surgucheva Belinda MacMahon Andrei Surguchov 
Synucleins belong to a family of small soluble proteins with chaperonic activity implicated in human diseases, but their normal function is not completely understood. Expression of ?, ? and ?-synucleins was analyzed i...
关键词：Lens CRYSTALLINS Synucleins PROMOTER CHAPERONES Heat Shock PROTEINS 
Distribution of Human Lens Crystallins and Their Sulphydryl Contents of Different Age in Two-dimension Electrophoresis被引量：1
《眼科学报》1999年第1期32-35,共4页S.C.Joseph Fu 
Purpose: To analyze water-soluble(WS) human lens proteins of fetus, adult and age-related cataract by two-dimensional IEF/SDSPAGE electrophoresis. Methods: DACM [ N- (7-Dimethylamino-4-methyl-3-coumarinyl) maleimide ]...
关键词：眼 晶体状 白内障 巯基 双向电泳 
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