REDUCTASES

作品数：11被引量：11H指数：2
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Recent Advances in Photoenzymatic Catalysis
《International Journal of Organic Chemistry》2024年第2期69-91,共23页Caiyi Xiang 
Photoenzymatic catalysis has become an emerging field in organic synthetic chemistry that provides eco-friendly alternatives to traditional methods. This comprehensive review examines the developing field of photoenzy...
关键词：Photoenzymatic BIOCATALYSIS BIOCATALYSTS ERED “Ene”-Reductases Nitroreductases FLAVIN 
Characterization of acid‑resistant aldo–keto reductases capable of asymmetric synthesis of(R)‑CHBE from Lactobacillus plantarum DSM20174
《Systems Microbiology and Biomanufacturing》2023年第4期634-646,共13页Jiufeng Zhu Yajun Bai Tai‑Ping Fan Xiaohui Zheng Yujie Cai 
Ethyl(R)-4-chloro-3-hydroxybutyrate((R)-CHBE),as a chiral intermediate,is widely used in the synthesis of various chiral drugs.In this study,we screened two aldo–keto reductases(LP-AKRs)from the probiotic Lactobacill...
关键词：Aldo–keto reductases Lactobacillus plantarum CHARACTERIZATION (R)-CHBE 
Phylogenetic diversity of NO reductases,new tools for nor monitoring,and insights into N_(2)O production in natural and engineered environments被引量：1
《Frontiers of Environmental Science & Engineering》2022年第10期23-37,共15页Sung-Geun Woo Holly L.Sewell Craig S.Criddle 
supported in part by a grant from the US National Science Foundation Engineering Research Center Reinventing the Nation's Urban Water Infrastructure(ReNUWIt)(Award No.EEC-1028968);in part by a grant from the NASA Center(USA)for the Utilization of Biological Engineering in Space(CUBES)(Award No.NNX17AJ31G).
Nitric oxide reductases(NORs)have a central role in denitrification,detoxification of nitric oxide(NO)in host-pathogen interactions,and NO-mediated cell-cell signaling.In this study,we focus on the phylogeny and detec...
关键词：N_(2)O Greenhouse gas NO reductase NO dismutase Primer Crystal structure 
Carboxylic acid reductases enable intramolecular lactamization reactions被引量：2
《Green Synthesis and Catalysis》2022年第3期294-297,共4页Zongmin Qin Xiaohui Zhang Xianke Sang Wuyuan Zhang Ge Qu Zhoutong Sun 
supported by the National Key Research and Development Program of China(No.2019YFA0905100);the National Natural Science Foundation of China(No.31900909);the Natural Science Foundation Applying a system of Tianjin(No.21JCJQJC00110)and Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(No.TSBICIP-CXRC-009);Mr Qu also thanks financial support from Youth Innovation Promotion Association,CAS(No.2021175).
As a versatile type of enzyme,carboxylic acid reductases(CAR)can not only reduce various carboxylic acids to aldehydes in cooperation with cofactors ATP and NADPH but also catalyze the synthesis of amides and esters i...
关键词：BIOCATALYSIS LACTAMS Carboxylic acid reductase Intramolecular cyclization Lactamization 
Two dehydroecdysone reductases act as fat body-specific 20E catalyzers in Bombyx mori被引量：1
《Insect Science》2022年第1期100-110,共11页Lang You Zhiqian Li Zhongjie Zhang Bo Hu Ye Yu Fangying Yang Anjiang Tan 
This work was supported by the National Science Foundation of China(31925007 and U1738110).
Periodic post-embryonic changes in insects, including growth, development and metamorphosis, are strictly controlled by many compounds, including steroid hormones. The biosynthesis and clearance of 20-hydroxyecdysone ...
关键词：Bm3DE3α Bm3DE3β Bombyx mori fat body 20-HYDROXYECDYSONE 
Tetraketide α-pyrone reductases in sporopollenin synthesis pathway in Gerbera hybrida:diversification of the minor function
《Horticulture Research》2021年第1期2962-2973,共12页Lingping Zhu Teng Zhang Teemu H.Teeri 
The structurally robust biopolymer sporopollenin is the major constituent of the exine layer of pollen wall and plays a vital role in plant reproductive success.The sporopollenin precursors are synthesized through an ...
关键词：SYNTHESIS implies outside 
Potential impact of combined inhibition of 3a-oxidoreductases and 5a-reductases on prostate cancer被引量：2
《Asian Journal of Urology》2019年第1期50-56,共7页Michael V.Fiandalo Daniel T.Gewirth James L.Mohler 
This study was supported by the DoD Prostate Cancer Research Program Award(No.W81XWH-16-1-0635);the National Cancer Institute(NO.P01CA77739 and NO.R21CA205108)to James L.Mohler;Post-doctoral Training Award(No.W81XWH-15-1-0409)to Michael V.Fiandalo;DoD Synergistic Idea Development Award(No.W81XWH-14-1-0520)to Dan T.Gewirth;NCI Cancer Center Support Grant to Roswell Park Comprehensive Cancer Center for the Bioanalytics,Metabolomics and Pharmacokinetics,Pathology Network,and Genomics Shared Resources(No.P30CA016056).
Prostate cancer(PCa)growth and progression rely on the interaction between the androgen receptor(AR)and the testicular ligands,testosterone and dihydrotestosterone(DHT).Almost all men with advanced PCa receive androge...
关键词：Androstanediol DIHYDROTESTOSTERONE DUTASTERIDE 3a-oxidoreductases Androgen deprivation therapy ABIRATERONE 
Biosynthesis of clinically used antibiotic fusidic acid and identification of two short-chain dehydrogenase/reductases with converse stereoselectivity被引量：4
《Acta Pharmaceutica Sinica B》2019年第2期433-442,共10页Zhiqin Cao Shaoyang Li Jianming Lv Hao Gao Guodong Chen Takayoshi Awakawa Ikuro Abe Xinsheng Yao Dan Hu 
supported by grants from the National Natural Science Foundation of China(31870032,3171101305,and 31670036);the 111 Project of Ministry of Education of the People's Republic of China(B13038);the JST/NSFC Strategic International Collaborative Research Program;Japanese-Chinese Collaborative Research Program;Chang Jiang Scholars Program(Hao Gao,2017)from the Ministry of Education of China;Guangdong Special Support Program(2016TX03R280);Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme(Hao Gao,2014);K.C.Wong Education Foundation(Hao Gao,2016);Guangzhou Science and Technology Project(201707010266,China);the Fundamental Research Funds for the Central Universities(21617495);Kobayashi International Scholarship Foundation;a Grant-in-Aid for Scientific Research from the Ministry of Education,Culture,Sports,Science and Technology,Japan(JSPS KAKENHI Grant Number JP15H01836 and JP16H06443)
Fusidic acid is the only fusidane-type antibiotic that has been clinically used. However,biosynthesis of this important molecule in fungi is poorly understood. We have recently elucidated the biosynthesis of fusidane-...
关键词：BIOSYNTHESIS FUNGI Fusidic acid Fusidane-type ANTIBIOTICS SDR 
Structural Basis for the Thermostability of Sulfur Oxygenase Reductases
《Chinese Journal of Chemical Engineering》2012年第1期52-61,共10页尤晓颜 孟珍 陈栋炜 郭旭 Josef Zeyer 刘双江 姜成英 
Supported by the National Natural Science Foundation of China (31070042,30870039,30921065);partially by Open Funding Project of the National Key Laboratory of Biochemical Engineering,China (2010KF-2)
The thermostability of three sulfur oxygenase reductases （SORs） was investigated from thermoacidophilic achaea Acidianus tengchongensis （SORAT） and Sulfolobus tokodaii （SORsT） as well as the moderately thermophi...
关键词：sulfur oxygenase reductase （SOR） thermostability homology modeling Acidianus SULFOLOBUS Acid- ithiobacillus 
Methionine sulfoxide reductase A: Structure, function and role in ocular pathology被引量：1
《World Journal of Biological Chemistry》2011年第8期184-192,共9页Parameswaran G Sreekumar David R Hinton Ram Kannan 
Supported by Grants from NIH (EY01545, EY03040);The Arnold and Mabel Beckman Foundation (to Hinton DR);a grant to the Department of Ophthalmology by Research to Prevent Blindness
Methionine is a highly susceptible amino acid that can be oxidized to S and R diastereomeric forms of methionine sulfoxide by many of the reactive oxygen species generated in biological systems. Methionine sulfoxide r...
关键词：METHIONINE SULFOXIDE REDUCTASES Hypoxia Protein interaction α CRYSTALLINS NEUROPROTECTION 
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