ABACAVIR

作品数：15被引量：4H指数：1
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相关领域：医药卫生化学工程更多>>
相关作者：王青张亚兰更多>>
相关机构：重庆大学复旦大学更多>>
相关期刊：《Open Journal of Genetics》《Science China(Life Sciences)》《药学进展》《Open Journal of Internal Medicine》更多>>
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Bioequivalence study of abacavir/lamivudine(600/300-mg) tablets in healthy Thai volunteers under fasting conditions
《Asian Journal of Pharmaceutical Sciences》2016年第1期233-234,共2页Ekawan Yoosakul Jaturavit Vattanarongkup Chutima Manamuti Bancha Chuasuwan Isariya Techatanawat Busarat Karachot Porranee Puranajoti 
Abacavir/lamivudine is a combination of two synthetic nucleoside analogues which is indicated in antiretroviral combination therapy for the treatment of human immunodeficiency virus(HIV)infection in adults and adolesc...
关键词：ABACAVIR LAMIVUDINE BIOEQUIVALENCE LC-MS/MS Pharmacokinetics 
Changes in Bone Mineral Density through 96 Weeks in Antiretroviral-Naïve HIV-1 Infected Patients Receiving Abacavir/Lamivudine and Raltegravir in the SHIELD Trial
《World Journal of AIDS》2014年第1期38-44,共7页Linda Battalora Amy Thomas Brian Wine Belinda Ha Benjamin Young 
Decreased bone mineral density (BMD) and osteoporotic fractures are areas of increasing concern among HIV-infected persons. Particular concern is the rapid decline in BMD after initiation of antiretroviral treatment (...
关键词：Bonedensity ABACAVIR HIV INTEGRASE LAMIVUDINE RALTEGRAVIR 
Prevalence of Human Leukocyte Antigen HLA-B*5701 in HIV-1 Infected Individuals in Brazil被引量：1
《Open Journal of Genetics》2014年第1期56-62,共7页Claudinéia de Araújo Cristina Valetta de Carvalho Miriam Estela de Souza Freire Amanda Yamaguti Ivens Cuiabano Scaff Fernando José de Souza Flávia Galindo Silvestre Silva Ricardo Sobhie Diaz Ismael Dale Cotrim Guerreiro da Silva 
This study was designed to establish the prevalence of HLA-B*5701 at HIV-1 infected individuals in Brazil. A total of 517 consecutive individuals were followed in this study from February 2009 through July 2011. The p...
关键词：IMMUNOGENETICS HUMAN IMMUNODEFICIENCY Virus HLA-B*5701 ANTIGEN HUMAN ABACAVIR 
Erratum to:Studies on abacavir-induced hypersensitivity reaction:a successful example of translation of pharmacogenetics to personalized medicine
《Science China(Life Sciences)》2013年第3期I0002-I0002,共1页GUO YongLi SHI LeMing HONG HuiXiao SU ZhenQiang FUSCOE James NING BaiTang 
The following statement should be included in the manuscript：The views presented in this article do not necessarily reflect those of the US Food and Drug Administration.
关键词：过敏反应 药物 个性化 药理学 翻译 诱导 勘误 美国食品 
Studies on abacavir-induced hypersensitivity reaction:a successful example of translation of pharmacogenetics to personalized medicine被引量：3
《Science China(Life Sciences)》2013年第2期119-124,共6页GUO YongLi SHI LeMing HONG HuiXiao SU ZhenQiang FUSCOE James NING BaiTang 
Abacavir is an effective nucleoside analog reverse transcriptase inhibitor used to treat human immunodeficiency virus(HIV) infected patients.Its main side effect is hypersensitivity reaction(HSR).The incidence of the ...
关键词：personalized medicine PHARMACOGENETICS drug safety ABACAVIR hypersensitivity reaction （HSR） HLA-B＊57：01 HLA-B＊57-01 screening 
Mechanisms involved in the Abacavir-mediated hypersensitivity syndrome
《Cell Research》2012年第12期1637-1639,共3页Anuska Llano Christian Brander 
The potentially life-threatening adverse reactions to Abavacir （ABC）, a nucleoside analog reverse transcriptase inhibitor for the treatment of H1V infection, have been known for several years to be limited to indivi...
关键词：超敏反应 综合征 机制 自身免疫性疾病 HLA-B 介导 不良反应 核苷类似物 
Trizivir (Abacavir/Lamivudine/Zidovudine) plus Lopinavir/Ritonavir Induction Therapy Followed by Trizivir-Alone Maintenance for HIV-1-Infected Patients: A 96-Week Pilot Treatment Simplification Study
《World Journal of AIDS》2012年第3期245-251,共7页Joseph C. Gathe Dean T. Martin M. Keith Rawlings Benjamin Daquioag John E. Fuchs Vanessa C. Williams Katrina L. Oie Gary E. Pakes 
Objective: The purpose of this study was to investigate whether switching HIV-infected patients stabilized on Trizivir (abacavir 300 mg/lamivudine 150 mg/zidovudine 300 mg) plus lopinavir/ritonavir 400 mg/100mg twice ...
关键词：Abacavir/Lamivudine/Zidovudine HIV-1 Infection Induction-Maintenance Strategy KALETRA Lopinavir/Ritonavir Trizivir 
Virologic and Lipoprotein Changes after Halving Ritonavir Boosting in HIV-Infected Patients Stabilized on Once-Daily Fosamprenavir plus Abacavir/Lamivudine
《World Journal of AIDS》2012年第2期109-116,共8页Dushyantha T. Jayaweera Gary E. Pakes 
Background: The effect of reducing ritonavir boosting doses on the efficacy and safety of fosamprenavir-based regimens has not been well studied. Methods: In a 52-week, phase 4, open-label, single-center pilot study, ...
关键词：FOSAMPRENAVIR HIV Infection LIPOPROTEINS Ritonavir 
Whole blood platelet aggregometry in HIV-infected patients on treatment with abacavir
《Open Journal of Internal Medicine》2012年第2期62-66,共5页Rosario Palacios Munoz Jose A.González-Correa Josefa Ruiz Enrique Nuno Manuel Márquez Jose P.de la Cruz Jesús Santos 
Purpose: To assess platelet activity in HIV-patients with and without antiretroviral therapy (ART), analysing the influence of the presence or absence of ABC in the regimen. Methods: Observational, pilot study, includ...
关键词：Antiretroviral Therapy ABACAVIR Cardiovascular Risk Platelet Activity 
abacavir 关键词：强过敏反应
《中国处方药》2008年第7期20-20,共1页许关煜（编译） 栾雪梅（编译） 
为避免出现危及生命的不良事件，美国FDA近日要求临床医师在使用一种名为abacavir的药物之前，要对患者进行基因筛查。
关键词：ABACAVIR 过敏反应 关键词 美国FDA 不良事件 临床医师 基因筛查 
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