supported by the National Natural Science Foundation of China(No.82073970);the National Key Research and Development Program of China(No.2020YFA0908000).
Hyperforin is a representative polycyclic polyprenylated acylphloroglucinols(PPAPs)that exerts a variety of pharmacological activities.The complete biosynthesis pathway of hyperforin has not been elucidated due to its...
supported by the Science Technology and Innovation Committee of Shenzhen Municipality of China(Grant Nos.JCYJ20170303154319837 and JCYJ20170412155447658);the Science Technology Innovation and Industrial Development of Dapeng New District,Shenzhen,China(Grant Nos.PT201901-18 and PT201901-20).
Protein prenylation plays a crucial role in plant development and stress response.We report the function of pren yltra nsferase a-sub unit in rice.Protein-protei n in teractions showed that the fam esyl-transferase(Os...
supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education,Culture,Sports,Science and Technology,Japan(JSPS KAKENHI Grant No.JP16H06443 and JP20H00490);Japan Science and Technology Agency(JST SICORP Grant No.JPMJSC1701);H.P.C.is a recipient of the JSPS Postdoctoral Fellowship for Foreign Researchers(ID No.P19413).
Prenyltransferase(PTase)enzymes play crucial roles in natural product biosynthesis by transferring isoprene unit(s)to target substrates,thereby generating prenylated compounds.The prenylation step leads to a diverse g...
financially supported by the National Natural Science Foundation of China (Grant No. 81273405);CAMS Innovation Fund for Medical Sciences (Nos. CIFMS-2016-I2M-3012 and CIFMS-2017-I2M-3-013)
Prenylflavonoids are valuable natural products that have diverse biological properties, and are usually generated biologically by multiple metabolic enzymes in nature. In this study, structurally diverse prenylflavono...
National Natural Science Foundation of China(Grant Nos.21572277,81573317 and 81703369);CAMS Innovation Fund for Medical Sciences(CIFMS-2016-I2M-3-012)
C-glycosylation and C-prenylation are two important C-C-bond forming reactions for preparation,diversification and structural modification of natural/unnatural products with pharmacological activities.Here,we describe...
Terpenoids are the largest and most diverse class of plant-specialized metabolites, which function in diverse physiological processes during plant development. In the biosynthesis of plant terpenoids, short-chain pren...
supported by the National High-tech R&D Program(863 Program)(Nos.2011AA10A206 and 2012AA101204-3);Program for New Century Excellent Talents in University(No.NCET-12-0930);Fundamental Research Funds for the Central Universities(No.XDJK2013A024);the earmarked fund for China Agriculture Research System (No.CARS-11-C-20)
Sweetpotato (Ipomoea batatas L. Lain.) ranks fifth among the most important food crops, after rice, wheat, maize and cas- sava, on a fresh-weight basis in developing countries (Scott and Maldonado, 1999). Sweetpot...