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COFACTOR: 作品数：50被引量：72H指数：4; 导出分析报告; 相关领域：生物学医药卫生更多>>; 相关作者：焦士会刘林初芹钱丽颖王祥民更多>>; 相关机构：北京奶牛中心新疆维吾尔自治区畜牧总站中国农业大学新疆农业大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金广东省自然科学基金制浆造纸工程国家重点实验室开放基金国家现代农业产业技术体系建设项目更多>>

Double-stranded DNA-nucleic acid dye complex-sensitized biocatalytic photosynthesis:Base pairing-switched regeneration of nicotinamide cofactor: 《Journal of Energy Chemistry》2024年第7期618-624,共7页Zhen Dong Yanying Wang Dan Li Peng Wu; the financial support from the National Natural Science Foundation of China (22274102 and 22325403);the Fundamental Research Funds from Sichuan University (2022SCUNL104);the Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University(2022A02); Photo-biocatalysis,the combination of photosensitization and biocatalysis,is an emerging solution for sunlight-based renewable energy.It is thus important to develop light antennas with both good light har-vesting and...; 关键词：PHOTOSYNTHESIS DSDNA SYBRGreenI TICT 2-phenylpropanol

Efficient production of 14α‑OH‑AD by engineered Mycolicibacterium neoaurum via coupled cofactor and reconstructed electron transport system被引量：1: 《Systems Microbiology and Biomanufacturing》2023年第2期358-369,共12页Chenwei Zhang Yanbing Shen Yuanyuan Gao Zehui Zan Min Wang; supported by the National Key R&D Program of China,Synthetic Biology Research(no.2019YFA0905300);the National Natural Science Foundation of China(21978221);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-001-08);the Innovative Research Team of Tianjin Municipal Education Commission(TD13-5013);the Tianjin Municipal Science and Technology Commission(21ZYJDJC00030).; 14α-hydroxy-androst-4-ene-3,17-dione(14α-OH-AD)is an important precursor for the synthesis of steroid drugs with anticancer and carcinolytic activity.Initially,14α-OH-AD was mostly synthesized by whole-cell ferment...; 关键词：14α-hydroxy-androst-4-ene-3 17-dione Mycolicibacterium neoaurum 14α-hydroxylase Electron transportation Coenzyme regeneration

Cofactor manipulation to drive biosynthesis of natural products: 《Synthetic and Systems Biotechnology》2022年第4期1073-1074,共2页Qidou Gao Mengyao Zhang Xiaobing Yang; This work was supported by supported by Natural Science Foundation of Shaanxi Province(2020JM-177);Chinese Universities Scientific Fund(2452018314).; Microbial production of value-added products is a promising alternative to plant-and chemical-based routes[1].However,only few of interested chemicals are producing at bulk scale with microbial cell factories(eg.artem...; 关键词：enable MANIPULATION INTERESTED

Cofactor Engineering Drives Natural Product Synthesis: 《Bulletin of the Chinese Academy of Sciences》2022年第2期122-122,共1页ZHOU Yongjin; In the past decade,advances in synthetic biology paved the way toward the sustainable synthesis of complex natural products.The baking yeast Saccharomyces cerevisiae has been widely used in food industry and has becom...; 关键词：PRODUCTS CONVENIENT SYNTHESIS

A specialized role played by a redox cofactor被引量：1: 《Engineering Microbiology》2022年第1期42-44,共3页Shengling Xie Lihan Zhang; supported by the National Natural Science Foundation of China(22177092,82003631);the Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang(2020R01004)to L.Z.; The redox cofactor𝛽-nicotinamide adenine dinucleotide(NAD)has been revealed to serve as a building block for the biosynthesis of an alkaloid natural product,altemicidin.The biosynthetic pathway investigation identifi...; 关键词：BIOSYNTHESIS Nicotinamide adenine dinucleotide Pyridoxal phosphate-dependent enzyme CYCLOADDITION

Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways被引量：10: 《Synthetic and Systems Biotechnology》2020年第3期200-205,共6页Zhu Li Dongqin Ding Huiying Wang Linxia Liu Huan Fang Tao Chen Dawei Zhang; This work was supported by the National Key R&D Program of China(2018YFA0900300);the Tianjin Science Fund for Distinguished Young Scholars(17JCJQJC45300);the Science and Technology Service Network(STS)Initiative of the Chinese Academy of Sciences(CAS)(KFJ-STS-ZDTP-065).; Optimizing the supply of biosynthetic precursors and cofactors is usually an effective metabolic strategy to improve the production of target compounds.Here,the combination of optimizing precursor synthesis and balanc...; 关键词：Escherichia coli TRYPTOPHAN Metabolic precursors Cofactor supply

Cofactor engineering in cyanobacteria to overcome imbalance between NADPH and NADH： A mini review被引量：4: 《Frontiers of Chemical Science and Engineering》2017年第1期66-71,共6页Jongmoon Park Yunnam Choi; Cyanobacteria can produce useful renewable fuels and high-value chemicals using sunlight and atmo- spheric carbon dioxide by photosynthesis. Genetic manip- ulation has increased the variety of chemicals that cyanobact...; 关键词：NADH-dependent enzyme NADPH-depen-dent enzyme TRANSHYDROGENASE site-directed mutagenesis enzyme engineering

Regulation of metabolism by the Mediator complex被引量：2: 《Biophysics Reports》2016年第2期69-77,共9页Dou Yeon Youn Alus M. Xiaoli Jeffrey E. Pessin Fajun Yang; The Mediator complex was originally discovered in yeast, but it is conserved in all eukaryotes. Its best- known function is to regulate RNA polymerase II-dependent gene transcription. Although the mecha- nisms by whic...; 关键词：TRANSCRIPTION MEDIATOR COFACTOR METABOLISM Insulin resistance OBESITY

Pyrroloquinoline quinone protects mouse brain endothelial cells from high glucose-induced damage in vitro: 《Acta Pharmacologica Sinica》2014年第11期1402-1410,共9页Zhong WANG Guo-qiang CHEN Gui-ping YU Chang-jian LIU; Aim： To investigate the effects of pyrroloquinoline quinone （PQQ）, an oxidoreductase cofactor, on high glucose-induced mouse endothelial cell damage in vitro. Methods： Mouse brain microvascular endothelial bEND.3 ...; 关键词：diabetes mellitus pyrroloquinoline quinone oxidoreductase cofactor high glucose endothelial cell ROS HIF-1α JNK

Characterization of 1,4-dihydroxy-2-naphthoyl-coenzyme A synthase(MenB) in phylloquinone biosynthesis of Synechocystis sp.PCC 6803: 《Science China Chemistry》2012年第1期98-105,共8页SONG HaiGang GUO ZhiHong; supported by GRF601209 from the Research Grants Council of the HKSAR government; The gene product Sll1127 is a predicted 1,4-dihydroxy-2-naphthoyl-CoA synthase catalyzing an intramolecular Claisen condensation in the phylloquinone biosynthesis of the cyanobacterium Synechocystis sp.PCC 6803.This p...; 关键词：DHNA-CoA synthase bicarbonate cofactor PHYLLOQUINONE MENAQUINONE BIOSYNTHESIS

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